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尾状核

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In the brain of adult rat, the positive immunohistochemical product of lSL-l (ISL-l-positive) was mainly located in the neuronal nucleus and found in discrete regions except to brain cortex, such as the Purkinje cell layer and the granular cell layer of cerebellum, the granular cell layer and the pyramidal cell layer of hippocampus, the mitral cell layer, the internal and external plexiform layer, the granular cell layer and the granular cell layer of olfactory bulb and so on, and several nuclei of the hypothalamus, midbrain and pons, such as claustrum, anterior olfactory nucleus, accumbens nucleus, caudate-ptamen, pallidum, substantia nigra, striatum, islands of Callaje, mammillary nucleus, anterior pretactal nucleus, habenular nucleus, amygdaloid nucleus, cuneate nucleus, rubral nucleus, gigantocellular reticular nucleus and so on.

在正常成年大鼠脑中,同源框基因islet-1表达产物(ISL-1)免疫组织化学阳性物质广泛分布于除大脑皮层外的神经细胞的细胞核内,ISL-1阳性神经元密集分布于小脑Purkinje细胞层和颗粒细胞层、海马的颗粒细胞层和锥体细胞层、嗅球的内丛层、外丛层、颗粒细胞层及僧帽细胞层等,另外在丘脑、中脑和桥脑的一些重要神经元核团均有分布,如,屏状核、前嗅核、伏核、尾壳核、苍白球、黑质、纹状体、Calleja岛、乳头体核、前顶盖前核、缰核、杏仁核、楔束核、红核网状巨细胞核等。

Glutamate and GABA in the substantia nigra may affect iron metabolism through DMT1-IRE and HP in the caudate putamen nucleus.

黑质的谷氨酸和GABA可能通过影响尾壳核DMT1-IRE和HP的表达影响纹状体尾壳核的铁代谢。

The CGRP-positive fibers in the MrD of the striatum connected dorsally with the bed nucleus of the stria terminals through the stria terminals, ventrally with the amygdaloid nucleus, and caudally with the CGRP-positive cell bodies in the lateral part of the substantia nigra and its dorsolateral area.(4) The CGRP-positive fibers connected mainly with the central amygdaloid nucleus, and less with the medial amygdaloid nucleus; the CGRP-positive fibers in the lateral border of the caudate putamen connected mainly with the central amygdaloid nucleus as well.

并与边缘区的CGRP阳性纤维带之间存在较多的横向联系纤维;(3)纹状体边缘区的CGRP阳性纤维向背侧通过终纹与吻侧的终纹床核联系,向腹侧与杏仁核的CGRP阳性纤维相连,向尾侧和中脑黑质外侧部及其背外侧区的CGRP阳性胞体相连;(4)边缘区的CGRP阳性纤维主要与杏仁中央核相联系,少量与杏仁内侧核相联系;尾壳核外侧缘的CGRP阳性纤维也主要与杏仁中央核相联系。

In the most caudal extent of the striatum, there was also a dense band of CGRP-positive fibers in the lateral border of the caudate putamen and the direction of the fibers was also dorsoventral. There are some transverse CGRP-positive fibers connecting the MrD and Cpu.

CGRP免疫阳性纤维分布越靠纹状体尾,则纤维越密集,且阳性带越宽;(2)在纹状体的最尾侧,除边缘区外,尾壳核的外侧缘也出现一条致密的阳性纤维带,与边缘区走向一致。

The CGRP-positive fibers ran dorsoventrally in the MrD and formed a dense band. The CGRP-positive fibers were more densely and widely distributed in the caudal part of the MrD.

结果发现:(1)CGRP免疫阳性纤维在纹状体内存在于纹状体的中部和尾侧,位于尾壳核和苍白球之间,即相当于纹状体边缘区的部位,形成一条明显的背腹方向走行的带状。

MethodsICH model was produced by stereotactically infusing 75 ul autologous fresh blood taken from rat femoral artery into the right caudate nucleus.

采用未抗凝新鲜自体股动脉血注入大鼠尾状核建立脑出血动物模型,模拟临床脑出血的自然状态。

Results The ten specific areas comprising hippocampus, parahippocampal gyrus, entohinal cortex, amygdale, the head of the caudate nucleus, middle temporal gyrus, cingulated gyrus, inferior parietal lobule, insula and dorsolateral prefrontal cortex could completely differentiate AD from normal controls by back-propagation neural network with eighteen training samples.

结果 海马、海马旁回、内嗅皮层、杏仁体、尾状核头部、颞中回、扣带回、顶下小叶、岛叶和前额背外侧区域,在训练样本数为18的情况下,利用神经网络能够达到100%的判别效果。

Positive correlation between verbal fluency and FA in both anterior limbs of internal capsule, left external capsule and the white matter of left occipital lobe were demonstrated by bivariate correlations.

结论DTI显示额叶癫疴患者右侧额叶MD值明显增高、右侧外囊、尾状核和双侧丘脑的FA值明显减低,提示额叶癫痫患者在上述区域可能存在细微病理改变,执行功能可能超出前额叶的范围。

Fifteen rats were implanted with C6 glioma spheroids in righ t caudate nucleus and the other five were used as controls.

正常组:5只;肿瘤组15只,在右尾状核接种C6细胞。

The marginal division was a flat fan-shaped structure with a volume of (0.48±0.02) mm3, a maximum rostral-caudate axis of 1.6 mm, a maximum dorsal-ventral axis of 2.158 mm, and a widest axis (the diameter at lateral-medial coronal brain section) of 0.17 mm. The marginal division also moved progressively externally from the rostral section to the caudate section, but its scope was larger than that of others. The whole marginal division changed evenly from the rostral section to the caudate one. Its flat structure widened progressively and its dorsal-ventral diameter narrowed gradually and became plate-shaped.

边缘区呈现一个片状扇形结构,体积为(0.48±0.02) mm3,最大嘴尾径为1.6 mm,最大背腹径为2.158 mm,最大内外径为0.17 mm;同尾壳核和苍白球一样从嘴侧到尾侧随着脑平面的增宽边缘区亦逐渐向外侧移位,其移位的幅度亦明显大于脑平面增宽的幅度;整个边缘区从嘴侧到尾侧呈均匀变化,其片状逐渐变宽,长度逐渐变小,从而形成一个盘状结构。

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