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Using mice, Guinea pig and SD rats, models of hypoxia, cerebral infarction, cardiac infarction and blood circulation stagnation are induced, analyse the mice' life in obturating condition; measure the renewals of mice with hemiplegia; analyse Guinea pig' cardiograph at vary time; analyse the variation of the swing of S-T and T wave ; measure the index o...

选用小鼠,豚鼠,SD大鼠分别复制缺氧、脑梗塞、心肌梗塞及&血瘀&模型,记录比较小鼠在密闭环境中的存活时间,测量小鼠偏瘫恢复数,记录豚鼠不同时间心电图,比较给药前后心电图ST段和T波振幅变化的差异,测定血液流变学指标。

In 16 month- aged mice, TP (50, 200mg/kg, ig) also showed potentiating effect on PFC response.

TP(200,400mg/kg,ig)可促进正常小鼠的PFC反应,并可对抗环磷酰胺(10mg/kg ip)和冷水(14±1℃)游泳应激所致的PFC反应降低;TP(50.200mg/kg)可使16月龄老年小鼠低下的PFC反应恢复至正常3月龄年轻小鼠水平。

The results showed that the weights of treated groups mice increased evidently; 17 kV HVPEF protracted mice' lives availably, and made the life protracting rate to 21.28%, but 23 kV electrostatic field accelerated the death of mice.

结果表明:(1)实验组小鼠体重增长较对照组显著迅速;(2)17 kV实验组有效的延长小鼠的生存期,生命延长率达21.28%,而23 kV电压组则明显的加快了小鼠的死亡。

Results:RWC can increase pain threshold of mice, prolong the latent period of body-spraining, but has no effect of the times of the spraining.

结果:精制吴茱萸胶囊能明显提高小鼠痛阈值。延长小鼠的扭体潜伏期,但对小鼠的扭体次数无明显影响。

The models of the ear swilling of mice and paw edema of rats were adopted to assay anti-inflammatory effect. Results 5-ASA(ig,75,150 and 300 mg.kg-1,for 3 d)significantly reduced the ear swelling of mice and the paw edema of rats and also decreased the writhing. 5-ASA at the dose of 300 mg.kg-1 ig,prolonged pain latency on hot-plate reaction.

结果 5-ASA片剂3种剂量(75、150及300 mg.kg-1,ig×3 d)对二甲苯诱导的小鼠耳肿胀度及蛋清诱导的大鼠踝关节肿胀度均有明显抑制作用;以上剂量还可明显抑制小鼠扭体反应,大剂量还可延长小鼠热板的舔足反应潜伏期。

We compared the difference of gene expression between thymus in one-and ten-month old Balb/c micee using DDRT-PCR. It was found that there would be a significant difference of gene expressions in murine thymuses.

我们采用差异显示反转录PCR技术对1月和10月龄Balb/c小鼠胸腺mRNA的差异表达情况进行了分析,共获得月龄差异表达的cDNA片段108条(其中90条源于1月龄小鼠胸腺中,而有18条源于10月龄小鼠胸腺中)。

After killing the mice, weights of thymuses and spleens, and the macrophage phagocytosis were detected. using sheep red blood cells as antigen, the amounts of antibody-producing cells in mice were counted. through lymphocyte conversion test, lymphocyte conversion ratios of spleen lymphocytes stimulated by cona in mice were determined.

处死后检测小鼠胸腺重、脾重、巨噬细胞吞噬功能;采用绵羊红细胞作为抗原,检测小鼠抗体生成细胞功能;采用mtt法检测小鼠脾淋巴细胞对cona刺激的转化能力。

The blood glucose levels in many strain animal models were determined after oral administration, with the models of diabetes induced by alloxan, of hyperglycemic mice induced by epinephrine and glucose, and normal mice.

采用四氧嘧啶所致糖尿病模型、肾上腺素和葡萄糖引起的高血糖小鼠模型,以及正常小鼠口服给药,测定各模型小鼠的血糖水平;并对GXTF进行了急性毒性试验。

The profile of gel-filtration of liver homogenate showed that zineis the main metal bound with MT in normal mice without giving copper,but copper isthe main metal bound with MT after oral administration of copper acetate.

分离正常小鼠肝脏和给铜后荷瘤小鼠肝脏中MT可见,小鼠未服用铜前肝脏中锌是MT的主要结合金属,而在给铜后肝脏中MT的主要结合金属是铜。

The mutagenicity of seed powder and seed oil of transgenic CryIA cotton to mammals and fish was evaluated in this study. The raw cotton seed powder or seed oil was mixed into mice and fish's diet. Cyclophosphamide and NaF were used as positive controls respectively. Regular cotton seed powder and seed oil were used as negative controls. The micronucleus frequency in mice bone marrow polychromatic erythrocytes and in eripheral erythrocytes of Zebrafish were assayed in this study. The sperm malformation rate in mice was also investigated.

摘 要:分别以环磷酰胺和氟化钠作为阳性诱变剂,以普通棉的棉籽粉及棉籽油作为对照物,同时设阴性对照组,以成年封闭群昆明种雄性小鼠和斑马鱼为实验材料,将棉籽粉或棉籽油掺入饲料中饲喂小鼠或斑马鱼,检测小鼠骨髓嗜多染红细胞(Polychromatic erythrocytes, PCE)微核率(Micronucleus frequency, MN‰)和精子畸变率,以及斑马鱼外周血红细胞微核率。

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