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Methods The antianaphylaxis activities of myricetin was measured by passive cutaneous anaphylaxis, dextran-induced itch and DNCB-induced delayed type hypersensitivity in mice,respectively.

采用小鼠同种、异种被动皮肤过敏反应、右旋糖酐致小鼠全身瘙痒反应和2,4-二硝基氯苯所致小鼠耳廓皮肤迟发型超敏反应实验,探讨杨梅素的抗过敏作用。

Rdf mice and normal wild-type Kunming mice were subjected to rotarystimulation (turning radius:0.6 m;angular volicity:180°/s;3 min per cycle;clockwise rotation alternated with the anticlockwise rotation)for 30 minutes toinduce motion sickness.

本课题拟利用rdf小鼠先天性视觉功能缺陷的特性,观察旋转运动刺激对正常野生型昆明小鼠和rdf小鼠中枢神经系统Fos蛋白及降钙素基因相关肽和已酰胆碱表达的影响。

Result The death rates of animals inoculated at axilla, medial thigh and sole after 50 days were KM mice 100%, 60% and 0%; BALB/c mice 80%,60% and 0%...

结果:腋下、股部内侧和脚垫接种组50d动物死亡率分别是:KM小鼠为100%、60%和0%;BALB/c小鼠为80%、60%和0%;C57BL/6小鼠为100%、50%和0%。

Tea catechins (310 mg/Kg, 155 mg/Kg and 77. 4 mg/Kg) distinctly inhibited the activities of serum bacteriolysin and celiac macrophagocyte (P.01), and reduced the formation of C3b and IC wreath in red blood cell, as well as total T cell and Th wreath in m ice.

茶儿茶素剂量为310mg/kg、155mg/kg、77.4mg/kg时,明显抑制小鼠血清溶菌酶及腹腔巨噬细胞的活性(P01);抑制小鼠红细胞C3b受体花环和IC花环的形成(P.05及P.01);抑制小鼠总T细胞花环和Th花环的形成(P.01);大、小剂量间差异显著,存在明显的量效关系。

For normal mouse, Yi Shen Granule could prolong the swimming time of mouse, the survival in Yi Shen Granule groups was more than that in model control group in same cold condition. For low-immune mouse, The eliminated rate of carbon granule in Yi Shen Granule groups rats was faster than that in model control group rats, it showed that phagocytosis was boosted up, the absorbency of upside liquid in Yi Shen Granule groups rats was more than that in model control group rats in hemolysin mensurated test, it indicated that more antibody was come into being by giving Yi Shen Granule.

益肾颗粒可以延长小鼠游泳时间;增加在同一寒冷条件下,相同时间内小鼠的存活数;对免疫力低下小鼠,给药组动物的碳粒廓清指数增大,反映吞噬功能增强;在血清溶血素含量测定试验中,给药组动物的上清液吸收值增大,说明机体产生的抗体较多。

Objective To investigate the action of GoLiLingSan on anti-inflammation and anti-carcinogen.Methods The model of acute inflammation was made on rats or mice by xylol,croton oil and carrageen in the model of chronic inflammation was made by cotton-pellets,and the model of tumor was made by S 180 and H 22 .The action of anti-inflammation,anti-carcinogen and the rate of life extension were observed.

目的 探讨高丽灵散的抗炎及抗癌作用方法用二甲苯、巴豆油、角叉菜胶造成、小鼠急性炎症模型;用棉球肉芽肿造成小鼠癌症模型,用S 180 、H 22 瘤株造成小鼠癌症模型,观察高丽灵散的抗炎、抗癌作用及生命延长率。

Methods The model of acute inflammation was made on rats or mice by xylol,croton oil and carrageen in the model of chronic inflammation was made by cotton-pellets,and the model of tumor was made by S 180 and H 22 .The action of anti-inflammation,anti-carcinogen and the rate of life extension were observed.

用二甲苯、巴豆油、角叉菜胶造成大、小鼠急性炎症模型;用棉球肉芽肿造成小鼠癌症模型,用S 180 、H 22 瘤株造成小鼠癌症模型,观察高丽灵散的抗炎、抗癌作用及生命延长率。

The ear edema of the normal and adrenalectomized mice induced by croton oil, vascular permeability formed by histamine in mice and hind paw edema caused by Carrageenin in rats were used to determine the inhibition to acute inflammnation.

提取物对急性炎症的抑制作用采用巴豆油引起的正常小鼠和摘除肾上腺小鼠的耳肿胀、组胺引起的小鼠毛细管通透性以及角叉菜胶引起的大鼠足肿胀进行分析。

RESULTS Xiaocuoling at the concentration of 2.5、5.0、10.0g.kg-1 obviously inhibited the paws swelling induced by carrageenin in mice and the granuloma with cotten pellet in rats,decreased the penetration of blood capillary caused by histamine,increased the activity of peroxide hydrogenase in RBC,reduced the reaction of the torsive body induced by acetic acid in mice,and had no effects on the serum concentrations of testosterone of serum in male rats.

结果:消痤灵颗粒 2.5、5.0、10.0g.kg-1可显著抑制角叉菜胶所致的小鼠足趾肿胀和大鼠棉球肉芽肿,降低由组胺诱导的小鼠皮肤毛细血管通透性的增加,提高红细胞过氧化氢酶的活力。对乙酸致小鼠扭体反应有抑制作用。对雄性大鼠血清睾酮含量无影响。

Corton oil,inhibit the rat foot swelling induced by carrageenin,It could increase the mice pain threshold induced by hot plate and inhibit theobviously anti-inflammatory and analgesic effects.

可明显抑制巴豆油所致小鼠耳廓肿胀和角叉菜胶所致大鼠足跖肿胀,能明显提高热板法小鼠痛阈,对甲醛疼痛模型小鼠舔足反应

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