小高

Topotecan is an effective agent for SCLC when used as monotherapy or in combined treatment, but myelosuppression such as leucopenia and thrombopenia was relatively severe. Although it has been recommended as a second-line agent for recurrence of sensitive SCLC, more clinical trials are needed to define its role in first-line treatment.

拓扑替康治疗小细胞肺癌有确切临床疗效，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，但具有相对高的致白细胞和血小板下降的骨髓毒性，已被认为是治疗化疗敏感的小细胞肺癌患者复发的二线推荐药物，但是作为一线用药仍然需要更多的实践来证实。

Conclutions Topotecan is an effective remedy for treatment of small cell lung cancer, both single topotecan and combined regimen has the same effect as the traditional first-line regimen, though myelo-suppression such as leucopenia and thrombopenia is more sever, the adverse effect is tolerated. Though it has been recommended as second-line agent for chemo-therapy sensitive small cell lung cancer, there needs more clinical studies to verify its role in first-line.

结论拓扑替康是在小细胞肺癌的治疗中有确切临床疗效的药物，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，虽具有相对高的致白细胞和血小板下降的骨髓毒性，但毒副作用可耐受，已经被认为是治疗对化疗敏感的小细胞肺癌患者的二线推荐药物，但是作为一线用药仍然需要更多的临床证据来证实。

RESULTS: After six weeks of implantation, x-ray film showed high-density signal, osteoid tissue formed under histological examination. Large amount of new bone were formed and connected to trabecularism 8 weeks after implantation in the experimental group.

结果 实验组6 周时大体标本浅红色， X 线片有较高密度阻射影像，组织学检查可见有新骨形成； 8 周时大体标本呈红色，质硬， X 线阻射影像密度更高，镜下可见大量新骨形成并相互连接成骨小梁样结构，骨细胞位于陷窝中。

The growth of plantlets with the height of 1-2 cm and 3-4 leaves was compared on MS basal medium containing various organic compounds, including banana, carrot, potato, coconut water, and tryptone. The result showed that the growth of oncidium plantlets was the best on medium containing banana, potato and tryptone altogether with respect to their plant height, leave number, root number, root length, fresh weight, and dry weight. The next better media were the control and the Banana medium, followed by the Potato medium.

另外取高约1-2公分，带3-4片叶片的分化小苗，培养於含不同浓度有机添加物（香蕉、胡萝卜、马铃薯、椰子水、及tryptone）的半量MS培养基，以探讨最适合文心兰瓶苗生长的培养基，试验结果显示，在同时含香蕉、马铃薯及tryptone三种成份的培养基生长的小植株不论在株高、叶数、根数、根长、鲜重、及乾重均较其他培养基为佳；不含添加物之1/2MS培养基、及含香蕉的培养基次之，而在含马铃薯之培养基较差。

Crude death rate is 201.55 per 100 thousand, and standardization is 184.04 per 100 thousand, which is 43.93% higher than the average level of the whole country. The standardization are as follows: hepatoma (53.57 per 100 thousand), lung cancer (47.76 per 100 thousand), gastric cancer (31.17 per 100 thousand), breast carcinoma (5.18 per 100 thousand), colorectal cancer (8.6 per 100 thousand). Monitoring indicates that the aggravation of water, atmosphere, small marine products, and the unhealth life habits are the main facts. Earlier screening profits diagnosis and prevention beforehand.

结果 慈溪市近十年恶性肿瘤死亡率逐年上升，位全死因的第一位，粗死亡率为201.55/10万，标化死亡率184.04/10万，比全国平均高43.93%，恶性肿瘤顺位及标化死亡率以肝癌(53.57/10万)、肺癌(47.76/10万)、胃癌(31.17/10万)、乳腺癌(5.18/10万)、结直肠癌(8.6/10万)，大气、水、土壤、蔬菜、小海产品监测表明：水质、环境的恶化及本市区域的大气、小海产品局部污染和不良卫生习惯是恶性肿瘤发生的主因，早期筛查利于早发现、早预防。

According to calculated results of this"System",three major rich areas of "large scale" unswept remaining oil in waterflooded bedded sandstone reservoirs have been determined:1.the unswept remaining oil in top of waterflooded positive rhythm reservoire with high viscosity oil;2.the unswept remaining oil in side parts and corners of oil reservoirs;3.the unswept remaining owing to development of non-proportionably each substratums in a series of strata.

利用抽象地质模型及相应的典型油层参数加油藏数值模拟加油藏工程加数理统计的研究方法，研究出了&注水多层油藏小层层内与平面波及评价系统&，利用这个系统的计算，确定出了注水多层油藏&大尺度&未波及剩余油的三大富集区：①注水高粘正韵律油层顶部未波及剩余油；②边角影响未波及剩余油；③层系内由于各小层物性差异开采不均衡形成的未波及剩余油。

The middle and lower parts of woodland and grassland had higher soil water contents during rainy season, which resulted from smaller evapotranspiration and more infiltrated water with a lower gradient. However, upslope runoff infiltration was another reason for hillslope with a lower cover ratio, such as bare land.

雨季林草地坡中下部土壤水分含量较高的原因，可能主要与其蒸散较小且坡度较缓导致入渗水量较多有关；但是对于植被覆盖度较低的坡地，坡中下部土壤水分含量较高还与上方来水有较大的关系。

As MEMS (Micro Electro-Mechanical Systems) technology progresses rapidly, the synergism between MEMS and biomedical technology becomes closer than ever before. When the uTAS was introduced in the last two decades, many microfluidic chips, microelectrodes, and microreactors are being studied for drug detection, environment detection, gene analysis etc. Due to its small volume, low pollution, low consumable and good portability, uTAS plays a very important role in biomedical, biochemical, environment engineering fields.

随着MEMS(Micro Electro-Mechanical System，微机电系统)制造技术的不断发展，生物医学与其之间的联系越来越紧密，自上世纪90年代初提出uTAS(Micro Total Analysis System，微全分析系统)之后，各种各样的微流控芯片、微反应器、微电极、微分离器等便大量涌现，广泛应用于药物检测、环境监测、基因分析等诸多领域中，并且由于其试剂消耗量少、检测效率高、环境污染小、体积小、易于携带等优点，在生物医学、化学、环境工程等领域受到越来越多的重视。

In this Asian population, smaller retinal arteriolar caliber was associated with hypertension and larger retinal venular caliber with cigarette smoking, dyslipidemia, hyperglycemia, and higher body mass index.

在这些亚洲人群中，较小的视网膜动脉管径与高血压相关，较大的视网膜小静脉管径与吸烟、血脂障碍、高血糖和高体重指数相关。

With featuring high efficiency 、low noise、easy control、anti-twist,and improved reliability, our propulsion products have been widely applied to ferryboat、tugboats、 workship and other special vessels that require high maneuverability for civil and military use.

产品具有推进效率高、噪音小、操纵优良及轴系防缠绕等特点，是一种理想的船用推进器，已广泛应用于渡轮、拖轮、工程船及各种操纵性能要求较高的民用和军用船舶。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。