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Based on the hypotheses that the tissue fluid and the cell in lacuna are incompressible,and the tissue fluid could flow between the lacunar through the canalicular,the pressure on the cell was obtained.

基于骨陷窝中组织液和细胞具有的不可压缩性,以及组织液通过骨小管在骨陷窝之间的流动,得到了细胞所受压力的新的表达式。

ResultsThe organization structure of experimental group was disorganized, cracked,and the bone trabecula was rarefactive and non-intact . There were a great number of empty lacune in bone trabecula.

结果实验组组织结构紊乱,破碎,骨小梁稀疏、不完整,有大量的空骨陷窝,而对照组骨小梁相对较完整、排列整齐,骨小梁中的骨细胞清晰可见,偶见空骨陷窝。

Results: At the concentrations of 0.1, 1 and 10 μmol/L, berberine dose-dependently suppressed the formation of TRAP-positive multinucleated cells, the TRAP activity and the osteoclastic bone resorption. The strongest inhibitory effect was exhibited at the concentration of 10 μmol/L, with the inhibiting rate of 60.45%, 42.12% and 72.69% respectively.

结果:小檗碱在0.1~10μmol/L范围内,浓度依赖性地抑制TRAP阳性多核破骨细胞的形成和TRAP活性,减少破骨性骨吸收陷窝的面积;在10μmol/L浓度下,对破骨细胞的抑制作用最强,对TRAP阳性多核破骨细胞的形成和TRAP活性的抑制率分别达到了60.45%和42.12%,骨吸收陷窝面积减少72.69%。

The organization structure of experimental group was disorganized, cracked and the bone trabecula was rarefactive and non-intact and there was a great number of empty lacuna in bone trabecula. While there was the reverse situation in the control group .

结果实验组组织结构紊乱,破碎,骨小梁稀疏、不完整,有量的空骨陷窝,而对照组骨小梁相对较完整、排列整齐,骨小梁中的骨细胞清晰可见,核大,位于中央。

ResultThe organization structure of experimental group was disorganized, cracked and the bone trabecula was rarefactive and non-intact and there was a great number of empty lacuna in bone trabecula. While there was the reverse situation in the control group .

结果实验组组织结构紊乱,破碎,骨小梁稀疏、不完整,有大量的空骨陷窝,而对照组骨小梁相对较完整、排列整齐,骨小梁中的骨细胞清晰可见,核大,位于中央。

Resultthe organization structure of experimental group was disorganized, cracked and the bone trabecula was rarefactive and non-intact and there was a great number of empty lacuna in bone trabecula.

结果实验组组织结构紊乱,破碎,骨小梁稀疏、不完整,有大量的空骨陷窝,而对照组骨小梁相对较完整、排列整齐,骨小梁中的骨细胞清晰可见,核大,位于中央。

The images of the 8th week's SEM and histological section showed that more CPC resorbedin the CPC-BMP group than in the CPC group. Trabecular in the CPC-BMP group, without the view of bone degeneration of osteonecrosis and resorptive lacuna, were stronger than in the other two groups.

在CPC-BMP组的骨小梁粗大,未见到明显的骨吸收陷窝,而且也未观察到在其他两组中常见的骨陷窝内骨细胞消失、骨坏死等骨质退化表现。

Results As compared with control group,the bone trabecula was thinner in experiment group,and the bone structure was rarefaction and disorder, with less bone mass.

结果 与对照组比较,实验组骨小梁纤细,结构稀疏紊乱,骨量少,部分骨小量断裂,成骨细胞和破骨细胞数量均增多,骨陷窝内破骨细胞活跃;骨密度下降。

Results: All 8 patients with INVM showed prominent excessive myocardial trabeculation and deep intrabecular. Endocardium of 25 patients with IDCM were smooth, except 2 patients, in which one had excessive myocardial trabeculations in beast apex, the other in lateral wall.

结果:8例INVM均有粗大的肌小梁和小梁间深陷的陷窝,25例IDCM 23例均未见粗大肌小梁及陷窝,1例在心尖部见轻度增粗的肌小梁,另1例在左室侧壁见数目有限的增粗肌小梁,并见其与假腱索相连。

SEM examination showed that the experimental group has regular spongiest structure,complete bone lacuna structure,partial broken os-teone and visible bone canaliculus, while the sham control group has disorderly structure, broken osrteone, little bone lacuna and total invisibility of bone canaliculus.

结果 X线片示A组右侧股骨头骨密度增高,透光区较小,B组骨密度减低,有大小不等透光区;ECT扫描示A组静态放射性分布中等浓聚,而B组静态图像放射性分布呈炸面包圈样改变,欠均匀;组织学检查显示A组骨空陷窝率、血管数、骨髓腔内脂肪细胞直径较B组明显改善(P<0.01);扫描电镜检查显示A组松质骨结构较规则,骨陷窝结构完整,部分骨板断裂,骨小管可见。B组结构紊乱不清,骨板断裂,骨陷窝少,骨小管消失。

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