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However, the conventional CMAC has an enormous memory requirement so that it cannot be applied to solve higher dimensional problems.

因此,本研究提出一个具有自组织能力之阶层式小脑模型类神经网路,它可以依据分析学习样本的分布,自动建立网路的记忆体配置,并藉由阶层式的学习架构,来有效降低记忆体的需求,使其具有解决高维度问题的能力,而此类神经网路架构亦具有可扩充性,可以在不影响其他网路的学习架构下,任意的增减输出节点的个数,此外,我们也提出了一个渐进式学习的演算法来训练此一类神经网路。

The protein and phospholipid constituent in membrane of neurocyte in brain of chicken with encephalomalacia was separated and studied with the method of SDS-PAGE electrophoresis and the method of high performance-thin layer chromatography respectively The fluidity of neurocyte membrane of chicken with encephalomalacia was determined for the first time The content of Ca and trace elements were determined in chicken encephalomalacia systematically and the status of Fe ion in cerebellum was observed. The activity of enzymes that were relative to metabolism of energy and neuro-medium in brain were checked systematically with the method of enzyme-histochemistry. Pathological examination was carried out by microscopic and ultramicroscopic observation. The apoptosis of neurocyte in brain was checked.

在进行临床观察、定期剖杀并检测体内V〓含量、体重和脑重的基础上,重点研究了与神经损伤有关的以下几个方面的内容:系统地检测了体内自由基代谢和抗氧化系统功能的变化;首次采用SDS-PAGE电泳法分离并检测了雏鸡脑软化症神经细胞膜蛋白组分,并以高效薄层层析法检测神经细胞膜磷脂组分;测定了脑软化症雏鸡神经细胞膜的膜流动性;首次系统检测了脑软化症雏鸡体内钙及微量元素含量,并进行了小脑组织总铁离子状态观察;采用酶组织化学方法系统地观察了脑组织中与脑能量代谢和神经递质有关的酶的活性;对相关组织进行了病理组织学和超微结构观察;并对脑组织中神经细胞的凋亡进行了检测。

The expression of Bax and Bcl-2 in cerebellum cortex and bathypelagic nuclei of the ovariectomized SD rat were up-regulated and down-regulated respectively, and the expression of the 2 proteins was regulated to normal after the rats were treated with 17β-estradiol.

结果显示,摘除双侧卵巢后,SD大鼠小脑皮质及深层核团中Bcl-2的表达有不同程度的降低,而Bax的表达出现不同程度的上升;给予外源性17β-雌二醇治疗后,2种蛋白的比例基本恢复正常。

The distributions of Hup A into rat brain tissues following intranasal dosing were compared with those after intravenous and intragastric dosing by tissue homogeneization.

结果大鼠鼻腔给药血浆AUC0→6h为静注的0.94倍,但脑脊液AUC0→6h为静注和灌胃的1.3和2.3倍;大鼠鼻腔给药后大脑、海马、小脑、左右嗅球的AUC0→6h分别为静注的1.5,1.3,1.0,1.2和1.0倍,为灌胃的2.7,2.2,1.9,3.1和2.6倍。

Lipomatous tumors in internal auditory canal and cerebellopontine angle are very rare; low-grade papillary adenocarcinoma of endolymphatic sac origin is rarely reported and has low malignant potential.

脂肪瘤样迷离瘤是一种发生在内耳听神经管或桥小脑角非常罕见的由脂肪、纤维、平滑肌、横纹肌以及神经成分组成的良性肿瘤。内耳内淋巴囊来源的低级别乳头状腺癌是发生在内耳内淋巴囊的特别罕见的低级别肿瘤。

To investigate the gene mutation of clinical and neuroelectrophysiological characteristics in Machado-Joseph disease. The gene mutation was detected in 45 patients diagnosed as spinocerebellar ataxia and 30 "healthy relatives". Brain stem evoked potentials, visual evoked potentials and motor conduction velocity and sensory conduction velocity were performed on MJD.

为了解Machado-Joseph病基因突变及临床的神经电生理特点,对16个诊断为遗传性小脑性共济失调家系的45例病人及30例家系的&正常&人作MJD基因突变分析,检出MJD基因的病人行肢体运动及感觉神经传导速度、脑干诱发电位,视觉诱发电位的检查。

Objective Machado-Joseph disease/Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by an expansion of polyglutamine tract near the C-terminus of the MJD1 gene product, ataxin-3. The precise mechanism of the MJD/SCA3 pathogenesis remains unclear.

目的 马查多-约瑟夫病/脊髓小脑共济失调3型,是由 MJD1基因产物ataxin-3的C-末端的多聚谷氨酰胺发生重复扩展突变而引起的一种常染色体显性遗传的神经退行性疾病,目前它的发病机制还不清楚。

The trilobed structure of the brain, lying posterior to the pons and medulla oblongata and inferior to the occipital lobes of the cerebral hemispheres, that is responsible for the regulation and coordination of complex voluntary muscular movement as well as the maintenance of posture and balance.

小脑脑的三裂叶状组织,位于脑桥和延髓之后脑半球的枕叶下面,负责调节和协调复杂的自发肌肉运动,同时负责保持身体姿势的平衡支配心脏的副交感神经发源于延髓的迷走神经核。

According to the asymmetry and nonlinearity of the symmetrical valve controlled asymmetrical piston system, in order to improve control precision of the system, the work characteristic of the system is analyzed, then a new control method based on the cerebellar model articulation controller is advanced, and the CMAC compound controller is designed.

针对对称阀控非对称缸系统的不对称性和非线性,为了提高系统控制精度,分析了该系统的工作特性,提出了基于小脑模型神经网络的控制策略,设计了CMAC复合控制器;为验证CMAC复合控制器的有效性,进行了实验研究,并与普通的PID控制器进行比较。

The two can cause ultrastructural pathogenesis widely in many organs and tissues such as hepar, pancreas, lien, ren, pulmo, cerebral, cerebellum, cor, muscular and so on, of them ,caused by i~olates YG97 and Y98 more obvious in epithelial cells of digestive tract and unobvious in epithelial cells of respiratory tract ,but ultrastructural pathogenesis caused by NDV strain F48E8 ,more obvious and more serious in glandularis and muscularis ventriaculi and in epithelial cells of respiratory tract .

将鹅源分离株YG_(97)、鸡源分离株Y_(98)和NDV强毒株F_(48)E_8感染SPF鸡,运用扫描电镜和透射电镜观察该二株病毒对机体细胞的影响,结果显示三株禽副粘病毒均引起机体肝、胰、脾、肾、肺、小脑、大脑、心和肌肉等实质器官组织细胞的超微病变,其中YG_(97)和Y_(98)引起消化道粘膜上皮细胞发生微绒毛脱落、纤毛脱落、分泌颗粒增多、细胞游离面破溃等显著的超微病变,引起气管粘膜上皮细胞的不显著超微病变;F_(48)E_8强毒株引起胃粘膜显著而严重的超微病变;还引起气管粘膜上皮严重的超微病变。

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