小脑的

Objective:To study the effect of long-term administration of CBZ on the structure and function of rats' cerebellum.

目的 ：研究长期服用卡马西平对大鼠小脑结构及功能的影响。

The most common reported clinical symptoms are: hearing impairment (95%), cerebellar ataxia (88%), pyramidal signs (76%), dementia (24%), anosmia (17%), anisocoria (10%) and sensory signs (13%).

最常见的临床表现为：听力损害（95%）、小脑性共济失调（88%）、锥体束征（76%）、痴呆（24%）、嗅觉丧失（17%）、瞳孔大小不等（10%）、感觉症状（13%）。

Objective: To discuss the molecular mechanism of hereditary cerebellar ataxia in waddles mouse.

目的：探查引起Waddles小鼠遗传性小脑性共济失调的突变基因。

Objective To explore SCA3 gene mutation in the patients with inherited spinocerebellar ataxia.

目的 探讨遗传性脊髓小脑型共济失调病人SCA3基因突变的意义。

Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73～79. The fragments of abnormal alleles were 380～402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18～40, fragments from 202～270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

结果检出10个家系25例病人及1例症状前18岁女孩有MJD基因突变，CAG三核苷酸重复73～79次，异常等位基因片段长380～402bp，均为杂合子；正常人CAG三核苷酸重复18～40次，等位片段长200～270bp，电生理发现MJD的SCV减慢比MCV明显，而下肢的MCV、SCV又较上肢明显，BAEP、VEP均有不同程度的潜伏期延长或波的异常；MJD的父亲遗传早于母亲，进展也较块，临床以小脑性共济失调为突出症状，其次为构音障碍、突眼等，肌肉萎缩仅见于晚期病人；MRI示小脑萎缩较明显，脑干萎缩并不严重，未见明显的颈髓萎缩。

Meanwhile the function of antioxidant defense system increased to enhance the ability for clearing free radical and antagonized the damage to organism from free radical. So the activity of GSH-Px and T-AOC enhanced. But the compensative ability was limited and the activity of GSH-Px decreased abruptly and the T-AOC was not increased further in cerebellum of chicken with encephalomalacia. This showed that it existed the exhaustion of GSH-Px in cerebellum of chicken with encephalomalacia.

在体内自由基蓄积的同时，机体抗氧化系统功能出现代偿性增强，提高自由基的清除能力，以对抗自由基对机体的损伤，表现为GSH-Px活性和T-AOC的增强，但机体的代偿能力是有限的，发病雏鸡小脑中GSH-Px活性的突然降低和T-AOC的不再增高，表明GSH-Px在发病雏鸡小脑中存在耗竭现象。

Results (1) 6 cases of Tuberous Sclerosis. Diffused subependymal nodular calcification lesions were found in all cases on unenhenced CT. 4 patients are 2 pairs of mother/child relationship. Both of the two mothers are found to suffer from renal angiomyolipoma.(2)1 case of neurofibromatosis showed abnormal spinal canal: scoliosis of thoracic and lumbar spine, concave change of vertebral posterior border. Bilateral renal hypogenesis was found in this patient. Diffused hyper-density lesions were found in kidney and fatty accumulation was found in back skin.(3)6 cases of Sturge-Weber syndrome. On unenhenced CT, curving and strip-shaped calcifications were found along the parietal and occipital gyrus.

结果 ①结节性硬化6例，所有病例CT平扫见两侧脑室室管膜下多发小结节状高密度钙化灶，其中4例为两对母子关系，并见两位母亲合并有肾脏错构瘤，；②神经纤维瘤病1例，MRI表现为椎管异常，胸腰段脊柱侧弯，椎体后缘呈明显的切凹改变；伴有双肾发育不良，CT示肾内多个高密度影，背部皮肤多量脂肪堆积，③脑颜面血管瘤综合征6例， CT可见顶枕部沿脑回分布的弯曲的条状高密度钙化，部分延伸致侧脑室内，增强后见病灶内有扭曲的条状和结节状明显强化的血管影；④小脑血管瘤病4例，影像学表现为小脑内大囊、小结节样占位性病变。

The fibres of the corticospinal tract, which run craniocaudally in the dorsal pons, the pontine tegmentum, and the superior cerebellar peduncles ventrally, were all preserved, this differential involvement therefore being responsible for the cruciform appearance on MRI.

译：脑桥神经元和横桥纤维严重减少，造成脑桥基底部和小脑中脚的苍白和萎缩。上下走行于脑桥背侧的皮质脊髓束、脑桥背盖部、腹前侧的小脑上脚/结合臂均未受累。这种差异性受累是MRI上出现十字征的原因。

In the neural networks control, the structure and the working principle of the cerebella model articulation controller are discussed firstly, and then based on the mutual supplements and the similarities between FCMAC and fuzzy logic,fuzzified cerebella model articulation controller is proposed. The learning control system based FCMAC are introduced in detail. Through the example of FCMAC used in the swinging up a pendulum control, the excellent control effects are demonstrated.

在神经网络控制方面，本文主要研究了小脑模型关节控制器，并进而根据CMAC与模糊逻辑的互补性与相似性，提出了模糊小脑神经网络控制器，详细讨论了FCMAC的学习控制系统与FCMAC的自学习机理，通过FCAMC对倒单摆控制的具体例子表明，FCMAC控制具有优良的控制效果和强的鲁棒性。

To explore the microdissection of the cerebellopontine angle as well as to study the advantage and disadvantage of the retrosigmoid approach and the retrosigmoid suprameatal approach, the relationship among the facial nerves, inter-medium nerves, anterior inferior cerebellar artery and petrosal vein were studied, and two approaches particularly also were explored from fifteen dry skulls and ten wet skulls, along the approach of RSA and RSSMA.

本研究旨在了解桥小脑角的显微解剖；探讨枕下乙状窦后入路及乙状窦后-内耳道上入路的优缺点。本实验采用15例(30侧)干标本和10例(20侧)湿标本，按照枕下乙状窦后入路和乙状窦后-内耳道上入路的所涉及的解剖区域，解剖观测面神经、中间神经、小脑前下动脉及岩静脉等诸多结构，并对神经外科手术乙状窦后入路及乙状窦后。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！