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The most sensitive period of alcohol damage is during the brain growth spurt, the last trimenon of mankind fetation and the first two postnatal weeks in the rat.

研究发现酒精损伤的作用最敏感的时期正是脑生长发芽期,在人类为孕后三个月(相当于大鼠新生至生后两周),在这个时期,短暂的酒精接触便会使皮质、海马、小脑的上百万神经元损害。

Results (1) 6 cases of Tuberous Sclerosis. Diffused subependymal nodular calcification lesions were found in all cases on unenhenced CT. 4 patients are 2 pairs of mother/child relationship. Both of the two mothers are found to suffer from renal angiomyolipoma.(2)1 case of neurofibromatosis showed abnormal spinal canal: scoliosis of thoracic and lumbar spine, concave change of vertebral posterior border. Bilateral renal hypogenesis was found in this patient. Diffused hyper-density lesions were found in kidney and fatty accumulation was found in back skin.(3)6 cases of Sturge-Weber syndrome. On unenhenced CT, curving and strip-shaped calcifications were found along the parietal and occipital gyrus.

结果 ①结节性硬化6例,所有病例CT平扫见两侧脑室室管膜下多发小结节状高密度钙化灶,其中4例为两对母子关系,并见两位母亲合并有肾脏错构瘤,;②神经纤维瘤病1例,MRI表现为椎管异常,胸腰段脊柱侧弯,椎体后缘呈明显的切凹改变;伴有双肾发育不良,CT示肾内多个高密度影,背部皮肤多量脂肪堆积,③脑颜面血管瘤综合征6例, CT可见顶枕部沿脑回分布的弯曲的条状高密度钙化,部分延伸致侧脑室内,增强后见病灶内有扭曲的条状和结节状明显强化的血管影;④小脑血管瘤病4例,影像学表现为小脑内大囊、小结节样占位性病变。

Results there were unconsciousness, respiratory rhythm disturbance and hyporeflexia of pupil light reflex immediately after injury, and reactiveness decrease and activity retardation still existed even after resuming consciousness. at anatomical scene, subarachnoid hemorrhage or cerebroventricular haemorrhage were widespread. at an early stage, there were swelling, collapse, and axonal retraction ball formation at cortico-medulla junction, callosum, brainstem, and cerebellar white matter under microscope. but at the later stage, gitter cell proliferation and nest-like aggregation were major pathophysiological changes at focal brain tissue.

结果 伤后大鼠均即刻出现原发昏迷,其中2只于损伤后20 min内死亡,余持续时间1-30 min不等;伤后大鼠呼吸节律紊乱,瞳孔对光反射减弱或消失,醒后均有程度不等的反应性下降,肢体活动迟缓;肉眼可见广泛蛛网膜下腔出血或脑室出血;光镜下可见皮髓交界区、胼胝体区、脑干、小脑白质等部位的神经轴索有不同程度的肿胀、断裂、轴索球形成,后期有小胶质细胞增生,局部呈巢样聚集。

Methods Since 1995,1210 cases (including 67 cases of tumors) of trigeminal neuralgia had received the operation of nervous decompression and combing by approach of postauricular suboccipital to the cerebellopontine angle.

回顾性 分析 1210例三叉神经痛患者的临床资料,采用经内镜下耳后小切口乙状窦后入路小脑脑桥角显微血管减压梳理术式或

The expression of Bax and Bcl-2 in cerebellum cortex and bathypelagic nuclei of the ovariectomized SD rat were up-regulated and down-regulated respectively, and the expression of the 2 proteins was regulated to normal after the rats were treated with 17β-estradiol.

结果显示,摘除双侧卵巢后,SD大鼠小脑皮质及深层核团中Bcl-2的表达有不同程度的降低,而Bax的表达出现不同程度的上升;给予外源性17β-雌二醇治疗后,2种蛋白的比例基本恢复正常。

The sensorimotor representation of the body is known to be ipsilateral in the anterior lobe and bilateral in the posterior cerebellum.

身体感觉的物态化已知是位於小脑前叶的同一侧以及左右对称在后小脑区。

The cytoarchitectonic organization ofprojections to the insular cortex and the amygdala from the parvicellular ventroposterior nucleus of the thalamus andtheparabrachial nucleus in the rat was investigated by means of horseradish peroxidase -tracing technigue; The relationship of origins of afferents to the insular cortex and the amygdala from the PBN was studied by using the retrograde transport of two fluorescent tracers; Thesynaptic connections of axonal terminals with the neuronsof the PBN were observed by means of electron microscopy.

GI主要位于岛皮质的尾侧部,DI和AI主要位于首侧部;VPpc是位于丘脑腹后核和内侧丘系之间的带状区,所含细胞较小(平均14u),其内侧部称为腹后内侧核小细胞部,其外侧部称为腹后外侧核小细胞部;PBN位于小脑上脚周围,由三部分组成:外侧亚核、内侧亚核和Kollikor-Fuse核,其中,PBl被分为7个区、PBm被分为3-4个区;杏仁核主要由三个细胞群组成:皮质内侧核群、基底外侧核群和中央核,中央核又有内侧部、外侧部和外囊部之分。

3D MDD patients showed significantly lower gray matter density than controls in right medial frontal gyrus, right temporal pole, bilateral putamen and globus pallidus, bilateral cerebellum. After treatment, gray matter density in right superior frontal gyrus, bilateral precentral gyrus, temporal pole, putamen and globus pallidus, and cerebellum in patients were still significantly lower than controls.

发作期抑郁症患者右侧额内侧回和同侧颞极、双侧壳核/苍白球和双侧小脑的灰质密度较正常人低;治疗后右侧额上回、双侧中央前回、双侧颞极、双侧壳核/苍白球和双侧小脑的灰质密度仍较正常人低。

Other brain regions showing increasedpostsurgical activity were the contralateral parietal cortex,bilateral pulvinar and ipsilateral medial dorsal nucleus ofthe thalamus, contralateral putamen, contralateral superiortemporal gyrus, ipsilateral fusiform gyrus, ipsilateral posteriorlobe, and contralateral anterior cerebellar lobe.

术后活动性增强的大脑区域还有对侧的颅顶部的大脑皮层,两侧的丘脑后结节和下丘脑的背内侧核,对侧的壳核,对侧的上部颞侧脑回,同侧的梭状回,同侧的后叶和对侧的小脑前叶。

Methods The optimal displaying angles and the length of intracisternal segment of the oculomotor nerve were measured on multiplanar reconstruction images.

在多平面重组图像上测量动眼神经脑池段的最大长度及最佳显示角度,并在该MPR图像及其连续图像、标本图像、原始图像及3D-TOF序列图像上研究动眼神经与大脑后动脉、小脑上动脉、基底动脉、后交通动脉及部分占位性病变的关系。

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