小脑内的

The course will start with an overview of the central and peripheral nervous systems, the development of their structure and major divisions. The major functional components of the CNS will then be reviewed individually. Topography, functional distribution of nerve cell bodies, ascending and descending tracts in the spinal cord. Brainstem organization and functional components, including cranial nerve nuclei, ascending / descending pathways, amine-containing cells, structure and information flow in the cerebellar and vestibular systems. Distribution of the cranial nerves, resolution of their skeletal and branchial arch components. Functional divisions of the Diencephalon and Telencephalon. The course will then continue with how these various CNS pieces and parts work together.

这门课将会从中枢和周边神经系统构造的发展和主要的分化点来概述，中枢神经系统的主要功能将会在复习中个别地说明：神经细胞体的断层以及功能性的分布、脊髓内上升和下降神经束的特征学和功能分布；脑干组织和功能要素，包括脑神经核、上升和下降神经束走向、含胺基酸脑激素细胞的分布、小脑和内耳前庭系统的构造和资讯传导流；颅神经的分布、骨弓和腮弓的演化；间脑和终脑的功能与分类；这门课将会探讨这些不同的中枢神经系统如何一起作用。

Results there were unconsciousness, respiratory rhythm disturbance and hyporeflexia of pupil light reflex immediately after injury, and reactiveness decrease and activity retardation still existed even after resuming consciousness. at anatomical scene, subarachnoid hemorrhage or cerebroventricular haemorrhage were widespread. at an early stage, there were swelling, collapse, and axonal retraction ball formation at cortico-medulla junction, callosum, brainstem, and cerebellar white matter under microscope. but at the later stage, gitter cell proliferation and nest-like aggregation were major pathophysiological changes at focal brain tissue.

结果 伤后大鼠均即刻出现原发昏迷，其中2只于损伤后20 min内死亡，余持续时间1-30 min不等；伤后大鼠呼吸节律紊乱，瞳孔对光反射减弱或消失，醒后均有程度不等的反应性下降，肢体活动迟缓；肉眼可见广泛蛛网膜下腔出血或脑室出血；光镜下可见皮髓交界区、胼胝体区、脑干、小脑白质等部位的神经轴索有不同程度的肿胀、断裂、轴索球形成，后期有小胶质细胞增生，局部呈巢样聚集。

Comclusion: transpetrous presigmoid retrolabrinth approach was rational approach for surgery on petroclivus and -4- CPA; it抯 important for accomplish the surgery to study and master the anatomy and variance of this approach; there was relative anatomical relationship among those structure on posterior of petrous bone; AAMP was the extracranial mark of inflexion of TS and SS; LAM and PSC were obvious bone marks for operation; we can confirm the abraded range of petrous bone lean upon LAM and/or GSS beside abrading step by step as literature, and it抯 unnecessary and unrational to emphasize to show PSC if the surgical space was enough; preceding sigmoid sinus and high jugular bulb often appeared at right and would bring disadvantage effect; interspace ,between CN V and CNVII or CNVII and CNJXI, were available to reach clivus and manage the mass on the range.

经SS前迷路后入路是处理岩斜坡区、桥小脑角区病变理想的手术入路；研究和熟悉手术入路中的解剖结构及部分变异对指导手术十分必要；岩骨内测面的骨性结构之间有着相对稳定的空间关系；顶乳缝前角是SS和TS转接处在颅外的标志；IAM和PSC等结构可以作为手术中的重要骨性标志；以PSC确定岩骨的磨除范围是较安全和可靠的，但亦可以结合影像检查，以内耳道和乙状窦前缘为基点判定切除范围，如果操作空间足够，过分强调磨出半规管是不适当的；右侧GSS的宽度和深度较对侧大，SS前置和颈静脉球高位较对侧多见，这些都对右侧入路有不利的影响，但仍可以进行手术操作；三叉神经和面神经间隙及面l 神经和舌咽神经间隙方便到达斜坡并处理病变。l

Neurons treated with 20-mmol/L-theophylline did not show 180bp ladder characteristic of endonuclear activation on its DNA gel electrophoresis. The ［cAMP］i of the neurons rose after being incubated together with different concentration theophylline (5-80 mmol/L) for 15 minutes in CO2 incubator and the prometed range relied on the dose of theophylline.

100％，量效关系有高度显著性(P.01)，EC50=2.97mmol/L；经茶碱(20mmol/L)处理的细胞，其DNA凝胶电泳带没有&梯子&状分布；与不同浓度茶碱（5-80 mmol/L）在CO2培养箱孵育15 min，小脑颗粒神经元内cAMP均升高，且是剂量依赖性的。

Results The clinical manifestations of TOBS comprised transient unconsciousness, vertigo, dyskinesia of eyeball, abnormality of pupils, dyskinesia of limbs, hemianopsia or cortical blindness, ataxia and memory impairment. MRI showed the local infarction in thalami, cerebellum, midbrain, pons, occipital lobe, temporal inner surface. The features of DSA were occlusion or stenosis in basilar artery and vertebral artery.

结果 TOBS的临床主要表现为一过性意识障碍、眩晕、眼球运动障碍及瞳孔的变化、肢体运动障碍、偏盲或皮质盲、共济失调及记忆功能损害；磁共振显示梗死灶在丘脑、小脑、中脑、脑桥、枕叶、颞叶内侧面；数字减影血管造影显示为基底动脉及椎动脉闭塞或狭窄。

Following small injections into the caudal part of the insular cortex, the retrogradely labeled neurons were mainlyseen in the parvicellular ventroposterior lateral nucleus of the thalamus, thecentral lateralsubdivision of the PBN, theouter part of the external medial subdivision of the PBN, and the contralateral PBme.

将HRP注入岛皮质首部，标记细胞见于VPMpc和PBN：VPMpc的标记细胞多位于其内侧部，大小为10-15u，以梭形细胞为主，还有圆形和三角形细胞，标记的纤维末稍较少见；PBN的标记细胞主要位于PBl腹侧区和PBm中央区，即PBN腰区，个别细胞散在于小脑上脚内，有少量标记纤维末稍。在PBN其它亚核很少见到标记成分。

Neuronalα4β2 nicotinic acetylcholine receptors are the most widespread subtypes in central nervous system.α4β2 nAChRs mainly exist in procerebrum, parietal lobe cortex, temporal lobe cortex, hippocampus, basal ganglion and cerebellum.

神经元烟碱受体α4β2亚型是中枢神经系统分布最为广泛的烟碱受体亚型，占脑内与烟碱有高亲和力的nAChRs的90%，主要分布在前脑、顶叶和颞叶皮质、海马、基底神经节和小脑。

Results in 18 cases（39.13%）,cwi appeared as wedge-shaped areas on ct scan or mri,the infarcts located at marginal zones between the anterior and middle cerebral arteries and were usually associated clinical with hemiparesis,transcortical motor aphasia and dementia.

脑分水岭梗死（cerebral watershed infarcts，cwi）多发生在脑内大血管供血的交界区或边缘带，或大脑中动脉的皮层支与深穿支供血的交界区，偶见于小脑的两条动脉供血交界区的脑组织。

Furthermore, we found that the Sema3F-triggered growth cone attraction was abolished by inhibition of the cGMP signaling pathway but not by inhibition of the cAMP signaling pathway, and the attraction was suppressed when elevating the intracellular cGMP level.

而且，在组织块共培养中，分泌Sema3F的细胞团能使小脑颗粒细胞偏向它迁移。我们发现Sema3F的吸引性作用在cGMP信号通路被抑制时受阻断，在细胞内cGMP水平增加时被削弱。

The cerebellum consists of five distinct concentric layers: white matter, internal granule layer, Purkinje cell layer, molecular layer, and external granule layer in young rodents.

在年幼的啮齿类动物中，小脑包含5种不同的集中分布层：白质、内颗粒细胞层、浦肯野氏细胞层、分子层和外颗粒细胞层。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。