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Transport signal in a soluble cargo protein (for example, a secreted protein that passes through the lumen) is a region that binds to the lumenal domain of a transmembrane cargo receptor, which in turn has an cytoplasmic domain that binds an adaptor protein. Interaction between the cargo and the coat

我们已经有了几种类型的信号的细节:要求一种构像用于蛋白质通过胞吞作用成为细胞内的一部分;一种氨基酸序列使得蛋白质到达内质网;和一种修饰使得蛋白质到达溶酶体(小的膜体,在那里蛋白质降解,见后面)。

Importantly, we demonstrate that phagosomes containing internalized cell corpses are unable to fuse with lysosomes in vps-18 mutants.

因此,在凋亡细胞的清除过程中,具有正常降解活性的胞内体和溶酶体与含凋亡细胞的吞噬小体之间的正常融合,对于凋亡细胞的及时清除是至关重要的。

Ovary oblong; style linear, persistent; stigma capitate. Utricles ovoid-oblong, ovoid, or subglobose, falling off with tepals and bracteoles.

子房长圆形;花柱线形,宿存;柱头头状胞果卵球形的长圆形,卵球形,或近球形的,与花被和小苞片一同脱落。

Our study showed that EGFprotein was mainly localized in the cell plasma of distal tubules and Henle'sloops and EGF mRNA was distributed not only in the nucleuses of above sitesbut also in a few nucleuses of interstitial cells and glomerulus cells.

本研究表明EGF蛋白主要位于髓袢和远曲小管细胞胞浆,而EGFmRNA除了位于上述部位的细胞核中外,在少数间质细胞、肾小球细胞细胞核内也有少量表达。

The cell in acidic situation presented a degenerative chang-ment,such as an increased lipid drop and empty cavity in the cell plasma,a py-knotic nuclei,the dilatation of the endoplasmic reticulum and Golgi saccules,mi-tochondrial swelling the number of ribose decrease,and the ribose dissociated inthe plasma,a lot of swallowing cavity,the fibric material decreased accompany-ing with the acid being stronger.

随培养基pH逐渐下降,上述过程因受酸性阻抑而延缓,细胞增殖速度也受影响,处于酸性环境中的软骨细胞呈退行性变化,表现为细胞浆内脂质颗粒与小泡增多、细胞核皱缩、核仁浓染、内质网线粒体膨胀、核糖体数目减少,且与粗面内质网结合的少,游离在胞浆中的多。

Most sperm nuclei eventually developed into the male pronuclei, just like the normal sperms, except sperm nuclei in a few zygotes kept dense throughout the fertilization process. Dense chromosome body was seen at the nuclear area during the prophase of first mitosis, and in the middle of spindle at metaphase of first mitosis.

精子入卵后形成精核,大多能够逐渐解凝、液化并膨大,最终形成形态正常的雄性原核,但在第一次卵裂早期退化成浓缩的染色质小体,并在胞质分裂时随机地分配到其中一个子细胞里的分裂沟附近。

Histologically, all tumors were composed of compacted small uniform round cells, with honycomb nests and cell-free islands of neuropil matrix within the tumor.

组织由密集的小圆形细胞组成,胞浆透明,有核周晕,呈蜂窝状结构,并有无细胞性神经原纤维岛特征。

At experimental equilibrium volume, the total energy of CaTiO〓 increased with the displacement of Ti along [001] direction and the lowest energy point is always at zero displacement of Ti. However, with a 10% volume expansion, the displacement of Ti along [001] direction results in a shallow, but well-defined double energy well and ferroelectricity appears.

钛酸钙在实验晶胞体积下,钛离子沿[001]方向的位移不会引起总能量的降低,当体积膨胀10%时,钛离子的位移会引起系统的总能量的降低,在一定的位移时总能量呈现极小值,即出现铁电性。

The reticulated vessel which has large cavity has thicker wall due to more elastic fibers and more smooth muscles and its endothelium is cuboidal epithelium which has rotundity karyons. But the reticulated vessel which has small cavity has thinner wall due to less elastic fibers and less smooth muscles and its endothelial cells are flat epithelial cells which have long-shuttle-shaped karyons. In some regions, the ducts are very small in diameter and thin of wall, and they become blood sinus in the end.

管腔大者,管壁厚,弹性纤维、平滑肌纤维多,内膜靠腔面内皮细胞多成立方状,细胞核端位近圆形;管腔小者,管壁薄,弹性纤维、平滑肌纤维少,内皮细胞扁平、排列稀疏,胞核长梭形;一些区域管径极小,管壁极薄,成为开放的血窦,只允许一个血细胞通过。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。