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Calf liver extract could protect hepatocytes from damage induced by H2O2, the effect at a concentration of 500 mg/L was the most obvious.Key words:calf liver extract; H2O2; hepatocytes culture; hepatocytes injured; protective effect

小牛肝提取物对H2O2诱导的肝细胞损伤具有一定的保护作用,其中以浓度为500 mg/L时效果最明显。

In recent years, NAFLD animal models have been successfully established in many species such as rat, sand rat, mice, rabbit, and piglets induced by diet, total parenteral nutrition, and methionine choline-deficient. These models provide new opportunities to study the pathogenesis and treatment of metabolic syndrome associated with NAFLD/NASH.

近年来,在大鼠、沙鼠、小鼠、兔和小猪等动物种属成功地建立了食物、胃肠外营养与蛋氨酸胆碱缺乏等诱导的单纯性脂肪肝和脂肪性肝炎动物模型,这些模型为研究脂肪肝和脂肪性肝炎的发病机理与治疗提供了机会。

In recent years, NAFLD animal models have been successfully established in many species such as rat, sand rat, mice, rabbit, and piglets induced by diet, total parenteral nutrition, and methionine choline-deficient.

近年来,在大鼠、沙鼠、小鼠、兔和小猪等动物种属成功地建立了食物、胃肠外营养与蛋氨酸胆碱缺乏等诱导的单纯性脂肪肝和脂肪性肝炎动物模型,这些模型为研究脂肪肝和脂肪性肝炎的发病机理与治疗提供了机会。

Methods Porcine bile duct and ureter were treated using detergent sodium dodecylsulphate and 1% Triton X-100 to prepare the acellular lumens matrix. The toxic effects of different concentrations of acellular lumens matrix extract were tested by MTT to assess the proliferation of human scarfskin fibroblasts. The cytotoxicity of the target biomaterial was graded according to the national standards. The growth manner of the human intrahepatic bile duct endothelial cells seeded on the acellular lumens matrix was studied after 20 d under scanning electron microscopy.

采用十二烷基磺酸钠、Triton X-100处理封闭群小香猪输尿管和胆管,获得去细胞管腔基质支架材料; MTT法检测基质支架材料的不同浓度浸提液对细胞增殖的影响,并按医用生物材料细胞毒性分级标准进行评级;在基质支架材料上种植人肝内胆管上皮细胞,于接种后20 d通过扫描电镜观察人肝内胆管上皮细胞在支架上的生长情况。

Methods Spontaneous aged dementia mice were screened out from 21 months old Kunming mice and then were divided randomly into 4 groups, namely control, westernmedicine, lower dosage Bugan Yangsui formula and higher dosage Bugan Yangsui formula group.

从 21 月龄昆明种小鼠筛选出自发老年性痴呆鼠,随机分为 4 组即空白对照组、西药对照组、补肝养髓小剂量组、补肝养髓大剂量组、另设老年学习记忆正常组。

The results showed that the contents of glutamic-pyruvic transaminase and glutamic oxaloacetic transaminase in part of the dogs were high and spontaneous pathologic changes occurred in the important organs, such as lung, kidney and brain. The incidences of interstitial pneumonia, cerebral ependymitis and vascular infiltration were high. Cloudy swelling and vasular degeneration appeared in part of hepatocytes and epithelial cells of renal tubules.

实验结果为部分犬的肝功能谷丙转氨酶和谷草转氨酶偏高;肝、肺、肾和大脑等重要脏器有自发性病理改变;肺的间质性肺炎和大脑室管膜炎及血管围管性浸润发生率较高,部分肝细胞和肾小管上皮细胞呈现浊肿或空泡变等。

The animal model of fatty liver with different severity can be established by feeding fractionary small dose of CCl4 into rabbit stomach, which can be used for the study of quantitative diagnosis of fatty liver with the means of imageology.

给予兔分次小剂量CCl4灌胃可以建立不同程度的脂肪肝动物模型,适用于影像学进行脂肪肝定量诊断研究。

Management with light doses of propanolol was effective for hepatogenic gastric ulcer , however it has been unlikely to respond to tranditional therapy and prone to bleed because of portal hypertension.

肝源性溃疡难以治愈且易并出血,门静脉高压因素可能从中发挥的作用,小剂量心得安有助于肝源性溃疡愈合。

LCVP was beneficial for reducing blood loss and blood infusion during hepatic resection, and had less effect on hepatorenal function.

低中心静脉压可减少肝叶切除术中的出血和输血量,对肝肾功能的影响小。

In group B, a large amount of inflammatory cell infiltration in liver tissues were noted and hepatic cells showed spotty necrosis and bleeding under the light microscope; the electron microscope showed a significant decrease of mitochondria cristae, the broadness of endoplasmic reticula, hepatic cell necrosis and karyopyknosis.

B组光镜下可见肝组织大量炎性细胞浸润,肝细胞点状坏死及出血;电镜下可见线粒体嵴明显减少,内质网扩张,出现凋亡小体及核固缩。C组上述病理变化明显减轻。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。