小细胞性的

Results there were unconsciousness, respiratory rhythm disturbance and hyporeflexia of pupil light reflex immediately after injury, and reactiveness decrease and activity retardation still existed even after resuming consciousness. at anatomical scene, subarachnoid hemorrhage or cerebroventricular haemorrhage were widespread. at an early stage, there were swelling, collapse, and axonal retraction ball formation at cortico-medulla junction, callosum, brainstem, and cerebellar white matter under microscope. but at the later stage, gitter cell proliferation and nest-like aggregation were major pathophysiological changes at focal brain tissue.

结果 伤后大鼠均即刻出现原发昏迷，其中2只于损伤后20 min内死亡，余持续时间1-30 min不等；伤后大鼠呼吸节律紊乱，瞳孔对光反射减弱或消失，醒后均有程度不等的反应性下降，肢体活动迟缓；肉眼可见广泛蛛网膜下腔出血或脑室出血；光镜下可见皮髓交界区、胼胝体区、脑干、小脑白质等部位的神经轴索有不同程度的肿胀、断裂、轴索球形成，后期有小胶质细胞增生，局部呈巢样聚集。

In the present study, the cell wall pectin content, CEC of root apices and Al-induced secretion of organic acid anions from roots of 10 triticale cultivars differing in Al resistance were examined.

本文在筛选不同小黑麦品种铝敏感性的基础上，研究了根尖细胞细胞壁中的果胶、阳离子交换量及铝诱导的有机酸分泌在抗铝性中的作用。

Result:After removal of the bilateral lower molars, the remodeling and degenerative activities in different layers of the condyles increased, such as vesiculation of endoplasmic reticulum, distortion of mitochondria and increase of lysosome. Furthermore, the sequential arrangement of collagen fibrils was disturbed, the collagen network broke down and the proteoglycan granules decreased.

结果：细胞发生了不同程度的改建及退行性反应，如粗面内质网的扩张，线粒体肿胀，溶酶体增多等；基质中胶原原纤维的有序排列结构消失，胶原网受到破坏，同时蛋白多糖颗粒减少；基质中脂质小体及基质小囊等成分增多；负重区较非负重区的改变更显著。

Hubba is a powerful prediction tool for hub/essential proteins with a user-friendly interface.Hubba can decipher the critical keys inside biochemical pathways and complex network, there will be significant clues to provide candidates for gene knockout and potential drug-targets for developing novel treatment in cancer cells and emerging pathogens.

Hubba线上分析平台，可用以分析生物复杂网路交互作用系统中的重要枢纽分子，以图像化手法呈现重要性来对枢纽蛋白质排名，并显示这些重要结点之间的关连性，协助辨识疾病细胞内与感染过程中的重要网路次模组，及特定基因群所关连的小网路，提供网路医学研究与新的治疗方法的开发。

People often occur in elderly vascular sclerosis, high blood pressure sustained more easily lead to cerebral arteriosclerosis, vessel wall hyalinization appears fat, thus weakening the strength of the vessel wall, together with the blood of the structure of the wall is relatively weak, the middle vascular myocytes less, the lack of external elastic layer developed arterial adventitia easily occurred in the brain artery wall limitations small expansion, the formation of micro-miliary aneurysm.

人到老年血管常会发生硬化，持续的高血压更容易导致脑动脉硬化，血管壁出现脂肪玻璃样变，从而削弱血管壁的强度，加上脑血管壁的结构比较薄弱，血管中层肌细胞少，缺乏外弹力层，动脉外膜不发达，容易造成脑内小动脉壁发生局限性扩张，形成粟粒性微动脉瘤。

Results CsA clearly decreased creatinine clearance and increased urinary excretion of N-acetyl-β-D-glucosaminidase in rats as compared with those in the vehicle group. Morphologic changes consisted of vacuolization of tubular cell, expansion of the interstitium and interstitial fibrosis, hyalinization of afferent arterioles. Severity of the injury was related to the dosage of CsA. Striped interstitial fibrosis and arteriolopathy were more severe in the rats treated with CsA and low-salt diet than with CsA and normal diet.

结果 用CsA的大鼠出现尿量增多、内生肌酐清除率下降、尿N-乙酰-β-D-氨基葡萄糖苷酶排泄增多等；病理上表现为不同程度的细胞浊肿、空泡变性及灶性分布的间质纤维化和小动脉病变，随CsA剂量的增加，病变呈加重趋势；结合低钠饮食，CsA慢性肾毒性病变明显加重。

Methods and Results— Using a micro–single-photon emission computed tomography small-animal imaging system and a Food and Drug Administration–approved radiotracer ([indium 111] oxyquinoline, 111In-oxine), we demonstrate here that monocyte recruitment to atherosclerotic lesions can be visualized in a noninvasive, dynamic, and 3-dimensional fashion in live animals.

方法和结果——采用微单光子发射计算机断层摄影术的小动物成像系统和美国食品药品治理局认同的放射性示踪剂（111In-oxine），我们证实动物体内单核细胞向动脉粥样硬化损害处的聚集能够通过一种非侵入性，动态的，3维方式进行可视化观察。

Brown adipose tissue is a kind of thermogenic organ of nonshivering thermogenesis in small mammals. The key element in BAT heat production is the uncoupling protein, a unique protein located in the inner membrane of BAT mitochondria.

褐色脂肪组织是小哺乳动物非颤抖性产热的主要器官，该组织具有一个独特的非偶联呼吸机制，它是由细胞线粒体内膜上的解偶联蛋白所决定的。

Objective To study the influence of water soluble azone on proliferation and ultrastructure of human trabecular mashwork cells .

目的观察水溶性氮酮对体外培养的人眼小梁细胞增殖活性和超微结构的影响，寻找氮酮作用于眼部的安全浓度。

After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

在上述结果的基础上进一步给予SHR NOS特异性拮抗剂左旋亚硝基精氨酸后，血管(胸主、颈内、肾及肠系膜动脉)NO基础释放及激动剂刺激释放进一步减少，Ach刺激冠脉流量的增加和胸主动脉内膜NOS活性也进一步减少，血小板聚集程度及红细胞聚集指数显著上升，病理切片显示胸主动脉内皮细胞破坏明显，脑心肾组织内的血管进一步增厚甚至几乎阻塞，导致饲L-NNA的SHR缺血性及出血性脑卒中发生率显著高于对照SHR，脑体重比显著升高；心肌内出现明显的缺血梗塞疤痕灶，心体重比显著升高；肾小球明显萎缩、玻璃样变性，肾小管也变性甚至坏死，使肾硬化程度显著增加呈颗粒性固缩肾，肾体重比也显著减少。

I can not make it blossom and suits me

我不能让树为我开花

When temperatures are above approximately 80 °C discolouration of the raceways or rolling elements is a frequent feature.

当温度高于 80 °C 左右时，滚道或滚动元件褪色是很常见的特征。