小细胞性的

Abstract］ Objective:To study the effect of berberine on adhesion characteristic of PG cell line and to investigate possible mechanism of inhibiting tumor metastasis of berberine.

目的：研究小檗碱对高转移性人巨细胞肺癌PG细胞黏附特性的影响，以探讨其抑制肿瘤侵袭转移的可能机制。

All 7 cases were characterized by deposition of dystrophic or psammatous calcifications accompanied with chronic inflammatory cells infiltration in the stroma. In some cases, there was formation of germinal centers.

特徵性形态学表现为在胶原化的纤维组织间可见散在的钙化灶或砂砾小体，间质内伴有多少不等的淋巴细胞和浆细胞浸润灶，部分病例中可见生发中心形成。

The cells are arranged in anastomosing sheets or in small clusters, separated by a fibrous or loose edematous stroma.

细胞排列成吻合的片状或小簇状，隔以纤维性间质或疏松水肿的间质。

Now we have known that SARS-CoV encoded 11 varietal proteins. They have 4 constitutive proteins: spike protein, membrane protein, envelope protein and nucleocapsid protein. Spike protein trimer form spike and exsertion? virus peplos on the surface. Spike protein is archi-surface antigen component of virus, it has acceptor binding and membrane fusion activity. Spike protein has important effect at tissue tropism, cell-fusion and toxicity. Nucleocapsid protein can bind genome RNA to shape neucleocapsid. Membrane protein and envelope protein are necessary constituent to shape virus peplos. Spike protein is I-type membrane glycoprotein, it mediate virus binding with host cell epimembranal acceptor and to fuse host cell membrane.

SARS-CoV属于巢状病毒目、冠状病毒科，为单正链RNA病毒，基因组全长约29.7kb，已知编码11种蛋白，其中包括4种结构蛋白，分别是刺突蛋白、包膜蛋白、小包膜蛋白和核蛋白或核壳体蛋白。S蛋白三聚体形成突起，伸出包膜表面。S蛋白是病毒的主要表面抗原成分，具有受体结合和膜融合活性，在组织嗜性、细胞融合和毒力等方面起重要作用。N蛋白与基因组RNA结合形成核衣壳。M蛋白和E蛋白是包膜形成所必需的成分。

Under electron microscopic observation, capillaries of SFO are fenestrated ones, the endothelium of them are short of the tight junction, their basement membrane are not intact, the gaps between the endothelium and basement membrane are widened, to which the gaps within the endothelium are opened, the end feet of astrocytes surrond the capillaries not completely, and on the luminal surface of the endothelium some small vesicles are adhere to it, all of which suggesting SFO short of blood brain barrier .

在电镜下观察，穹窿下器的毛细血管为窗性毛细血管，内皮缺乏紧密连接结构，基膜薄而不完整，内皮与基膜之间的间隙宽大，内皮裂隙可通向此间隙，毛细血管内皮腔面可见贴壁小泡，星形胶质细胞脚板未完整包围毛细血管，这些结构特点提示SFO的血脑屏障不完整。

Under electron microscopic observation, capillaries of SFO are fenestrated ones, the endothelium of them are short of the tight junction,their basem ent membrane are not intact, the gaps between the endothelium and basement membrane are widened, to which the gaps within the endothelium are opened, the end feet of astrocytes surrond the capillaries not completely, and on the luminal surface of the endothelium some small vesicles are adhere to it, all of which suggesting SFO short of blood brain barrier.

在电镜下观察，穹窿下器的毛细血管为窗性毛细血管，内皮缺乏紧密连接结构，基膜薄而不完整，内皮与基膜之间的间隙宽大，内皮裂隙可通向此间隙，毛细血管内皮腔面可见贴壁小泡，星形胶质细胞脚板未完整包围毛细血管，这些结构特点提示SFO的血脑屏障不完整。

Now the research has made progress.(1) The meiosis stages of megaspore could be discriminated timely through observing the meiosis of microspore under the same environmental conditions, according to the association of female and male buds during development.

1首次提出利用雌、雄花芽发育进程的时序性相关性，以相同生境以及培养条件下的小孢子发育进程为参照，从而相对准确地实现白杨大孢子母细胞减数分裂进程即时判别的技术方法。

What was observed under a light microscope included: tumor cells were mulberry and micropapillaryshaped or it was of glandule tubular arrangement; there was obvious interspace between cancer nest and neighboring areas; micropapillary was empty of fiber blood vessel axes; immunohistochemical staining showed EMA positive location was both at outward surface of glandule duct and at micropapillarylike cancer nest.

光镜下特征性表现为肿瘤细胞呈桑椹状、微乳头状或小腺管样排列，癌巢与周围间质形成明显的空隙。微乳头缺乏纤维血管轴心。免疫组化染色EMA阳性部位在癌细胞巢团或微乳头状、腺管的外表面。

What was observed under a light microscope included: tumor cells were mulberry and micropapillary shaped or it was of glandule tubular arrangement; there was obvious interspace between cancer nest and neighboring areas; micropapillary was empty of fiber blood vessel axes; immunohistochemical staining showed ema positive location was both at outward surface of glandule duct and at micropapillary like cancer nest.

光镜下特征性表现为肿瘤细胞呈桑椹状、微乳头状或小腺管样排列，癌巢与周围间质形成明显的空隙。微乳头缺乏纤维血管轴心。免疫组化染色ema阳性部位在癌细胞巢团或微乳头状、腺管的外表面。

This study was designed to investigate the effects of microglia condition medium on neurons during kainate-induced excitotoxicity.

本论文为了探讨kainate所引发的兴奋性毒性过程中，小神经胶细胞条件培养液对神经细胞的影响。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新