小纤维状的

For example, when the proteins of the eyes' lenses lose their elasticity, we lose our ability to focus and need bifocal spectacles--one of Franklin's inventions.

这些基因中就有心脏病和癌症这两大致命杀手的基因，这些基因中同样也包含了导致囊肿性纤维化和镰状细胞血症这些小病的基因。

A fiber is a pliable hairlike strand that is very small in diameter in relation to its length.

纤维是柔韧的毛发状细丝，其直径相对于长度来说是非常小的。

RESULTS: Microscopically, the lesion consisted of abundant collagen fibrils, proliferated histiocytes and numerous infiltrated plasmocytes, lymphocytes and eosinophilic granulocytes. Fusiform or polygonal histiocytes had abundant, granular, eosinophilic cytoplasm or clear cytoplasm containing radially oriented strands or resembled xanthoma cells. Emperipolesis of numerous small lymphocytes was seen in the cytoplasm of some large histiocytes.

结果： 镜下可见丰富的胶原纤维和组织细胞增生以及大量浆细胞、淋巴细胞和嗜酸粒细胞浸润，组织细胞呈梭形、多边形，胞质嗜酸性颗粒状、放射条纹状或泡沫状，一些大组织细胞质内有多量小淋巴细胞。

RESULTS摘要: Microscopically, the lesion consisted of abundant collagen fibrils, proliferated histiocytes and numerous infiltrated plasmocytes, lymphocytes and eosinophilic granulocytes. Fusiform or polygonal histiocytes had abundant, granular, eosinophilic cytoplasm or clear cytoplasm containing radially oriented strands or resembled xanthoma cells. Emperipolesis of numerous small lymphocytes was seen in the cytoplasm of some large histiocytes.

结果摘要：镜下可见丰富的胶原纤维和组织细胞增生以及大量浆细胞、淋巴细胞和嗜酸粒细胞浸润，组织细胞呈梭形、多边形，胞质嗜酸性颗粒状、放射条纹状或泡沫状，一些大组织细胞质内有多量小淋巴细胞。

Mallory trichrism staining exhibited light blue samples. Eight weeks following repair, CT showed round blunt defect edges in the coronal position, which had bony pustute connection with gel materials. Density at the defect region significantly increased. 3D reconstruction suggested that defects became small. After hematoxylin-eosin staining, abundant fibrous connective tissue appeared in defect regions, with bony tissues. Mallory trichrism staining revealed that maroon mature bone tissues were found, surrounded by light blue chondroid tissues. Twelve weeks following repair, coronal defect regions were filled with callus. 3D reconstruction showed that defects were repaired. Defect region and surrounding bony tissues had bony connection, with thick bone trabecula and mature Haversian system.

修复后8周，冠状位CT显示缺损边缘圆钝，与凝胶材料有骨性突起连接，缺损处密度增高明显，三维重建显示缺损范围较之前有所减小；标本苏木精－伊红染色后缺损部可见大量含血管成分的纤维结缔组织，有骨样组织结构形成，Mallory三色染色显示有褐红色成熟骨组织形成，其旁边有淡蓝色软骨样组织修复后12周，冠状位CT显示缺损区基本被骨痂填满，三维重建示缺损基本修复；缺损区域和周围骨组织形成骨性结合，骨小梁粗大，哈弗氏系统成熟。

Results 6 patients with PAP presented with ground-glass opacification of the bilateral lungs on HRCT. Typical chest HRCT scan showed "map-like" lesions in 3 cases and "cobble stone-like" lesions in 3 cases. Multifocal consolidative opacities in the lungs were seen on HRCT in 3 cases. Lung biopsies from 6 patients with PAP revealed a prominent positive periodic acid-Schiff intra-alveolar exudates. There were normal alveolar spetasis in 3 patients while interstitial thickening, fibroblast hyperplasia, interstitial fibrosis in the others.

结果 6例患者在不同层面可见磨玻璃影，其中2例可见小结节影；3例表现为两肺斑片状磨玻璃影与周围肺组织分界清楚，呈地图样改变；3例因磨玻璃影与小叶间隔增厚交织成铺路石样改变；3例可见肺泡实变融合成密度较高的斑片状阴影，1例在肺泡实变区可见&空气支气管征&。6例患者活检肺组织在光镜下显示肺泡腔内充满大量块状或颗粒状嗜伊红物质，PAS染色阳性，AB染色阴性，其中3例肺泡间隔正常，3例肺泡间隔增宽，可见慢性炎性细胞浸润、成纤维细胞增生和胶原沉积。

The morphologic change of muscle fibers: At the early stage of denervation, the area of cross sections decreased, some muscle fibers turned into angular fibers, nuclei congregated around the center of the fibers. After 8 weeks of denervation, atrophic and hypertrophic fibers coexist. Collagen increases under the endomysium and between the fibers.

肌纤维的组织形态学变化：面部肌肉失神经支配早期，肌纤维的横截面面积变小，出现角状纤维，肌细胞核聚集，细胞核从肌纤维边缘移至肌纤维中央附近；失神经支配后期，肿胀与萎缩的肌纤维并存，肿胀的肌纤维的横截面成倍大于正常的肌纤维，而萎缩的肌纤维的横截面则成倍小于正常的肌纤维；有大量的角纤维存在，肌纤维之间有较多的结缔组织增生。

Resujts:① The distribution of lesions are mostly symmetrical, extensive, predominant in the middle and lower lung fields, and posterior areas in peripheral;② There are so many HRCT findings of lung, ILD is predominant: intralobular interstitial thickening 46 cases (100%), ground-glass opacity 41 cases (89.13%), peribronchovascular or centrilobular interstitial thickening 40 cases (86.96%), interlobular septal thickening 38 cases (82.61%), irregular linear opacity 37 cases (80.43%), small nodular opacity 34 cases (73.91%), subpleural line 27 cases (58.70%), bmnchiectasis or bronchiolectasis 19 cases (41.30%), patch opacity 18 cases (39.13%), expiratory mosaic sign 15 cases (32.61%), interface sign 14 cases (30.43%), honeycombing 12 cases (26.09%), emphysema or bulla 3 cases, cystic airspace suspected 1 case, and atelectasis suspected 1 case;③ Mediastinum and pleura: multiple small lymphonodi in mediastinum 41 cases (89.13%), pleural thickening or rough 38 cases (82.61%), esophagoectasis 11 cases (23.91%), unilateral little pleural fluid 1 case, and mediastinal emphysema 1 case.

结果：①皮肌炎肺部病变分布呈对称、广泛、偏中下、偏外后的特点；②肺部HRCT表现多样，以肺间质性改变为主：小叶内间质增厚46例(100%)，磨玻璃影41例(89.13%)，支气管血管束增宽或小叶核心增大40例(86.96%)，小叶间隔增厚38例(82.61%)，不规则纤维索条影37例(80.43%)，结节影34例(73.91%)，胸膜下线27例(58.70%)，支气管或细支气管扩张19例(41.30%)，斑片影18例(39.13%)，呼气相马赛克征15例(32.61%)，界面征14例(30.43%)，蜂窝影12例(26.09%)，肺气肿或肺大泡3例，单纯囊状气腔1例，肺不张l例；③纵隔及胸膜：纵隔小淋巴结影41例(89.13%)，胸膜增厚或毛糙38例(82.61%)，食管扩张11例(23.91%)，单侧少量性胸腔积液1例，纵隔气肿1例。

One eye (Vogt-koyanagi-harada syndrome) showed severe anterior uveitic reaction; One eye had fibrinous membranes on IOL, and white debris on IOL were found in 2 eyes.

结果术后矫正视力≥0.5者占80%，1眼(Vogt-小柳-原田综合征)术后出现较严重的前部葡萄膜炎症，1眼见IOL表面纤维素性渗出膜，2眼IOL表面见片状白色碎屑。

Recent studies showed that Rho GTPase played a key role in the reorganization of cytoskeleton and in Swiss 3T3 cells, Cdc42, Rac1 and RhoA, three members of Rho superfamily of small GTPase, regulated the polymerization of actin to produce filopodia , lamellipodia, stress fiber and focal adhension, respectively.

近年来的研究表明，Rho家族小G蛋白是细胞骨架肌动蛋白的重要调节因子，目前众多的研究集中在Rho小G蛋白家族成员中的Cdc42、Rac1和RhoA，其中Cdc42促进丝状伪足的形成，Rac1调节板装伪足的生成和膜皱缩，RhoA则促进粘着斑连接和张力纤维的装配。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失