小纤维

Results Osteoclast and osteoblast around trabecula of bones showed proliferation, shi1e fatty tissues in bone marrow decreased and hematopoietic tissue well-regenerated alter the hyperbaric oxygen-treated. Also juvenal osteocyte and collagen fibril were observed in early stage by electron microscope.

结果 多数骨小梁周围可见骨母细胞增生、偶见破骨细胞增生，髓腔内脂肪细胞逐渐减少，造血组织增生；电镜发现骨小梁内早期即出现幼稚骨细胞和胶原原纤维合成。

Results In the medium and high dose F0 groups, it was observed that the atrophy and incrassation of seminiferous tubule, decrease of spermatogenesis, hyperplasia of interstitial tissue, especially in high dose groups spermatozoon abnormality and nucleolus concentration in the rats testis after DU ingestion for 14 months. The changes became more severe with the prolongation of DU ingestion. Such changes occurred in filial rats (F1) after DC ingestion for 5 months. In the medium and high dose F0 groups, it was observed that a little atrophy of kidney glomerulus, hyperplasia of interstitial tissue after DC ingestion for 14 months, and kidney glomerulus fibrosis happened after DC ingestion for 20 months, such changes occurred in filial rats (F1) after DC ingestion for 5 months In the medium and high dose F0 groups, splenic germinal center and periarterial lymphatic sheaths were hyperplasia , companies with lymphopoiesis after DC ingestion for 7 months, splenic white pulp became more small and sparse after DC ingestion for 20 months.

结果 F0代的中、高剂量组大鼠摄入贫铀14个月后可见雄性的精曲小管萎缩，管壁增厚呈空虚网状，生精细胞层次减少，间质细胞增生，但仍见有精子生成；高剂量组可见到精子呈异型性改变，细胞核浓缩深染，且随着摄入时间延长改变愈趋明显；F1代大鼠摄入贫铀5个月后就有上述改变且更为严重。F0代中、高剂量组大鼠摄入贫铀14个月后肾小球轻度萎缩，间质增生明显，20个月时肾小球萎缩纤维化；F1代大鼠摄入贫铀5个月后就有上述改变。F0代中、高剂量组摄入贫铀7个月时脾脏生发中心和淋巴鞘增生，淋巴母细胞增生活跃，20个月时脾小体减少，生发中心稀疏；F1代大鼠摄入贫铀早期和晚期有类似改变。F0和F1代高剂量组摄入贫铀早期肝脏有炎症细胞浸润，晚期骨髓有核细胞减少，脂肪细胞增加。

It's a minuscule amount of electricity, but the output grows as more fibers are added.

它是很小很小的一个电量，但是输出随着纤维数量的增加而增加。

In the normal rats (n=5、6), CGRP-LI were mainly present in small and some medium-sized neurons and the primary afferent fibers and ter- minals in laminae Ⅰ,Ⅱ,Ⅴ,Ⅹ and Lissauer's tract of the spinal cord; GAL- and SP-LI were mainly present in small neurons and the superficial layers of the dorsal horn. After the adjuvant injection both CGRP-and SP-LI were in- creased corresponding to the development of arthritis. On day 2, CGRP-and SP-LI were moderately increased in laminae Ⅰ,Ⅱ and the posterior commis- sure of the spinal cord and small neurons in DRG, while SP was obviously in- creased in the superficial layers and DRG. On day 14, CGRP-LI were marked- ly enhanced in the above regions with the development of polyarthritis. Some- times many strongly stained long fibers could be seen in the posteriot commis- sure.

在DRG中，CGRP主要分布于小和中等神经元之中，SP和GAL主要分布于小神经元之中；2、注入弗氏完全佐剂（含冻干结核菌0.5mg）后第2天动物（各5~6例）产生具有明显红、肿、热、痛和痛敏的急性关节炎，免疫组化实验观察到注射侧脊髓背角和DRG中CGRP-和SP-LI明显增加；在佐剂后第14天，动物患肢肿胀、痛敏和自发痛均进一步加重，部分动物健肢也出现红肿，产生多发性关节炎时，脊髓背角浅层和DRG中CGRP-和SP-LI增加更为明显，并且在灰质后联合中可见许多深染的CGRP-LI长纤维；在佐剂后第21和28天，随着佐剂性关节炎的逐渐恢复，脊髓背角和DRG中CGRP-和SP-LI也接近正常。

In order to eliminate the effect of noise, wavelet-based denoising technique was used both on diffusion weighted images and noisy tensor field. We also compared the wavelet-based denoising method with the Gaussian smoothing, the traditional denoising method in image analysis.

为降低图像噪声对纤维跟踪的影响，分别采用小波去噪方法对扩散加权图像和张量场进行处理，并对小波去噪和传统的高斯平滑方法在扩散加权图像噪声抑制方面的作用进行了比较。

The stable clones are further identified by RT-PCR and Western blot; 6 MTT assay is used to investigate the effect of ZNRD1 on the cell growth of cells (AGS, SGC7901, MKN28, NIH3T3, GES-1); 7 Soft agar assay is used to investigate the effect of ZNRD1 on the clonality of cells (AGS, MKN28); 8 Nude mice assay is used to investigate the effect of ZNRD1 on the cell growth of gastric cancer cells (AGS, MKN28); 9 Flow cytometry is used to investigate the effect of ZNRD1 on the cell cycle distribution of cells (AGS, MKN28, NIH3T3, GES-1); 10 Flow cytometry is used to investigate the effect of ZNRD1 on the cell apoptosis of cells (AGS, MKN28, NIH3T3); 11 MTT assay is used to investigate the effect of ZNRD1 on the drug sensitivity of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR) in vitro; 12 SRCA is used to investigate the effect of ZNRD1 on the drug sensitivity of gastric cancer cells (SGC7901, SGC7901/VCR) in vivo; 13 Flow cytometry is used to investigate the effect of ZNRD1 on adriamycin accumulation of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR); 14 Transmission electron microscope is used to investigate the effect of ZNRD1 on the sensitivity of SGC7901 cells towards drug-induced apoptosis; 15 Flow cytometry and DNA ladder assay are used to investigate the effect of ZNRD1 on the sensitivity of cells (SGC7901, SGC7901/VCR, HL-60/VCR) towards drug-induced apoptosis; 16 Microarray is used to investigate the profiling of ZNRD1-responsive genes in gastric cancer cells (AGS, MKN28, SGC7901, SGC7901/VCR); 17 RT-PCR and Western blot are used to identify the results of microarray; 18 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of cyclin D1; 19 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of MDR1; 20 Kinase assay is used to investigate the effect of ZNRD1 on the activity of cyclin E-CDK2 kinase; 21 The antisensenucleic acids of p21 is used to inhibit the expression of p21, and flow cytometry is used to investigate the effect of p21 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 22 The antisensenucleic acids of p27 is used to inhibit the expression of p27, and flow cytometry is used to investigate the effect of p27 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 23 Liposome is used to up-regulate the expression of Skp2, and flow cytometry is used to investigate the effect of Skp2 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 24 Western blot is used to investigate the effect of ZNRD1 on the stability of Skp2 and p27 in gastric cancer cells; 25 MVD assay is used to investigate the effect of ZNRD1 on the angiopoietic activity of gastric cancer cells; 26 ELISA is used to investigate the effect of ZNRD1 on the expression of VEGF165 in gastric cancer cells; 27 The roles of DARPP-32 in MDR of gastric cancer cells are investigated using gene transfection, MTT assay, SRCA, flow cytometry and DNA ladder assay.

应用杂交瘤技术制备ZNRD1的首个单克隆抗体；2）利用RT-PCR、Western blot和免疫组化检测ZNRD1在胃癌组织、胃炎组织、正常胃上皮组织、胃癌细胞和正常胃组织上皮细胞中的表达；3）构建ZNRD1的小干扰RNA载体，并测序鉴定；4）利用脂质体将ZNRD1的真核表达载体及其空载体转染胃癌细胞（AGS、SGC7901、MKN28）和小鼠成纤维细胞（NIH3T3），G418筛选后进行鉴定；5）利用脂质体将ZNRD1的小干扰RNA载体及其空载体转染药敏胃癌细胞（SGC7901）、正常胃组织上皮细胞（GES-1）、对长春新碱耐药的胃癌细胞（SGC7901/VCR）、药敏白血病细胞（HL-60）、对长春新碱耐药的白血病细胞（HL-60/VCR），G418筛选后进行鉴定；6）利用MTT实验检测ZNRD1高/低表达对细胞（AGS、SGC7901、MKN28、NIH3T3、GES-1）生长的影响；7）通过软琼脂克隆形成实验检测上调ZNRD1对AGS、MKN28细胞克隆形成能力的影响；8）通过裸鼠成瘤实验检测上调ZNRD1对AGS、MKN28细胞体内成瘤性的影响；9）通过流式细胞仪分析ZNRD1高/低表达对细胞（AGS、MKN28、NIH3T3、GES-1）的细胞周期的影响；10）通过流式细胞仪分析上调ZNRD1对细胞（AGS、MKN28、NIH3T3）的凋亡的影响；11）通过MTT实验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）体外药物敏感性的影响；12）通过肾包膜下移植法检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR）体内药物敏感性的影响；13）通过流式细胞仪分析ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）内阿霉素蓄积和泵出的影响；14）通过透射电镜检测上调ZNRD1对SGC7901细胞凋亡敏感性的影响；15）通过流式细胞仪和DNA梯度试验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60）凋亡敏感性的影响；16）通过基因芯片检测ZNRD1高/低表达对胃癌细胞内基因表达谱的影响；17）利用RT-PCR、Western blot对基因芯片的结果进行鉴定；18）利用报告基因实验检测ZNRD1对cyclin D1的启动子活性的调节作用；19）利用报告基因实验检测ZNRD1高/低表达对MDR1的启动子活性的调节作用；20）利用激酶试验检测ZNRD1对cyclin E-CDK2 激酶活力的影响；21）利用反义核酸技术抑制p21的表达；通过流式细胞仪检测抑制p21对ZNRD1介导的细胞周期阻滞的影响；22）利用反义核酸技术抑制p27的表达；通过流式细胞仪检测抑制p27对ZNRD1介导的细胞周期阻滞的影响；23）利用脂质体转染法上调Skp2的表达；通过流式细胞仪检测上调Skp2对ZNRD1介导的细胞周期阻滞的影响；24）利用Western blot检测ZNRD1对p27和Skp2的蛋白稳定性的影响；25）利用微血管密度实验检测ZNRD1对AGS、MKN28细胞裸鼠移植瘤微血管形成的影响；26）利用ELISA检测ZNRD1对AGS、MKN28细胞培养上清和移植瘤匀浆中VEGF165含量的影响；27）利用脂质体转染法、MTT实验、肾包膜下移植法、流式细胞仪和DNA梯度试验检测新耐药相关分子DARPP-32对细胞（SGC7901、SGC7901/VCR、对阿霉素耐药的胃癌细胞SGC7901/ADR）多药耐药表型的影响；利用脂质体转染法和MTT实验检测下调ZNRD1对DARPP-32介导的胃癌多药耐药的调控作用。

Results In Hyacintn bletilla group fibroblastic cell hare small soma,a little spine.

结果 白及胶组成纤维细胞胞体较小，胞突少，多呈圆形，胞核较小。

Hyaline and erythrocytic casts, glycogen deposition in tublar epithelial cells, and renal interstitial fibrosis also were observed in model rats.

肾小管上皮细胞内有糖原沉积，肾小管蛋白管型和红细胞管型，肾间质纤维化，伴发间质脓肿形成。

Results: No fiber layer and inflammatory tissues around any inserted implants were founded. New-grown osteoid tissue appeared faster in Bio-Ti implants than pure titanium and matured bone tissues comprise bone trabecula and Haversian canals appeared in 6 weeks, while at least 12 weeks needed to form matured bone tissue in control groups.

结果：所有种植体周围没有发现明显炎症组织或形成纤维层，Bio-Ti种植体组新生类骨组织生长较快，并于6w时已形成含有骨小梁及哈弗氏小管结构的较成熟骨组织，对照组12w时新生骨组织基本成熟。

The results showed that under the given experimental conditions,the surface layer with richiron and poor copper was formed in the surface worn region of the semimetallic friction material,the depth of organic ingredient pyrolysis caused by friction heat in worn surfaces was atout 0.35mm; the semimetallic friction material containing 15%-20%of Cu had better wear-resistance,and can form a even and continuous transfer film of copper; crack peeling was the importantmechanism of the counterpart.

半金属摩擦材料具有摩擦系数稳定，耐磨性好，对环境污染小和对偶件表面损伤小等优点，但其在摩擦热和界面应力等因素作用下，表层会发生弹性变形，塑性变形，元素扩散，组分转移和摩擦化学反应等现象，因此，利用扫描电子显微镜X射线能量色散谱和差热－热重分析，对铜纤维增强的半金属摩擦材料与灰铸铁滑动摩擦表面层的特性作了分析研究，考察了表面层特性对摩擦损行为的影响。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。