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小红细胞

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After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

在上述结果的基础上进一步给予SHR NOS特异性拮抗剂左旋亚硝基精氨酸后,血管(胸主、颈内、肾及肠系膜动脉)NO基础释放及激动剂刺激释放进一步减少,Ach刺激冠脉流量的增加和胸主动脉内膜NOS活性也进一步减少,血小板聚集程度及红细胞聚集指数显著上升,病理切片显示胸主动脉内皮细胞破坏明显,脑心肾组织内的血管进一步增厚甚至几乎阻塞,导致饲L-NNA的SHR缺血性及出血性脑卒中发生率显著高于对照SHR,脑体重比显著升高;心肌内出现明显的缺血梗塞疤痕灶,心体重比显著升高;肾小球明显萎缩、玻璃样变性,肾小管也变性甚至坏死,使肾硬化程度显著增加呈颗粒性固缩肾,肾体重比也显著减少。

Biochemical indicator such as TG and SF were unregulated while 1 system or 2 system reduced in peripheral blood; Bone marrow hyperplasia showed active or active obviously. Complete morphological nucleated cells mature erythrocytes or platelet hemophagocytic cells were found in 100% marrow slides. Marrow hemophagocytic cells were quantified as 0.5 to 11 per micro liter Median 4.2 per micro liter. Phagocytes showed smaller size single nucleus on one side. Submitting as rings cell plasm showed gray or salmon pink and cell showed disorder fringes.

结果: 符合HPS者30例诊断为HPS早期21例;HPS早期有持续高热峰值≥38.5 ℃、发热期≥4天发病与感染相关;以病毒感染最多见,生化指标TG增高、SF增高;外周血细胞一系或二系减低;骨髓增生活跃或明显活跃,骨髓片(100%)找到吞噬了完整形态的有核细胞、成熟红细胞或血小板的噬血细胞骨髓噬血细胞0.5-11个/ul中位数4.2个/ul吞噬细胞体积偏小多为单个核核偏一侧,可呈印戒样,胞浆灰兰或淡红色,细胞边缘不整齐。

Biochemical indicator such as TG and SF were unregulated while 1 system or 2 system reduced in peripheral blood; Bone marrow hyperplasia showed active or active obviously. Complete morphological nucleated cells mature erythrocytes or platelet hemophagocytic cells were found in 100% marrow slides. Marrow hemophagocytic cells were quantified as 0.5 to 11 per micro liter Median 4.2 per micro liter. Phagocytes showed smaller size single nucleus on one side. Submitting as rings cell plasm showed gray or salmon pink and cell showed disorder fringes.

结果: 符合HPS者30例诊断为HPS早期21例;HPS早期有持续高热峰值≥38.5 ℃、发热期≥4天发病与感染相关;以病毒感染最多见,生化指标TG增高、SF增高;外周血细胞一系或二系减低;骨髓增生活跃或明显活跃,骨髓片(100%)找到吞噬了完整形态的有顾细胞、成熟红细胞或血小板的噬血细胞骨髓噬血细胞0.5-11个/ul中位数4.2个/ul吞噬细胞体积偏小多为单个核核偏一侧,可呈印戒样,胞浆灰兰或淡红色,细胞边缘不整齐。

Dialysers with copper membrane, polysulpone membrane and polypethyl methacrylate membrane were individually used, and the immune function indexes of erythrocyte RBC-C3b and RBC-IC in different timephase in the process of dialysis were observed....

结果:尿毒症病人的 RBC-C3b显著下降, RBC-IC显著增高。透析开始后,早期 RBC-C3b进一步下降,其后逐渐上升;而 RBC-IC早期逐渐增加,其后逐渐稳定。结论:Cu膜能明显地影响红细胞的免疫功能; Ps膜次之; PMMA膜对其影响最小。

It revealed that cell culture of JL94 hadnt agglutination to human group O, A, B and chicken, goose, simian, mice, guinea pig, goat, dog RBC.

血凝试验证明JL94不凝集鸡、鹅、猴、小白鼠、豚鼠、山羊、狗、人的O型、A型及B型红细胞。

We are sad cried, arrived in the evening, effort was done not have on my daughter body, send all over soft, be troubled by all the time, it is such pasts this day night the following day, I still have my Mom to holding the child in the arms to build a car directly with my wife went to city haemal institute, be in when us second when making detailed inspection to the daughter, the leucocyte that discovers a daughter is as high as 610 thousand, red blood cell has 30 thousand only much, the doctor says, your child is too small, if cure, the likelihood can have life risk at any time, if not cure, your child still can live a few days more, hear this news I am about to break down simply, my tear flowed, passed a little while, we let a doctor help us look for bed, let daughter be in hospital, the doctor says, miss your child this circumstance, you are spent namely 100 thousand 200 thousand 1 million, when your child is being treated, life is potential a few minutes of lives were done not have, your child is held in the arms do not answer Hubei, you spend the money in how, also be person money two sky, the doctor says: Do you have remedial money?

我们都伤心哭了,到了晚上,我女儿身上没了力气,浑身发软,一直闹,这天晚上算是这样过去了第二天,我跟我老婆还有我妈抱着孩子直接搭车去了市血液研究所,当我们在次给女儿做详细检查的时候,发现女儿的白细胞高达61万之多,红细胞只有3万多,医生说,你的孩子太小,如果医治,可能随时都会有生命危险,如果不医治,你的孩子还可以多活几天,听到这个消息我简直快要崩溃了,我的眼泪哗啦的就流了下来,过了一会,我们让医生帮我们找床位,让女儿住院,医生说,想你们孩子这个情况,你就是花10万20万100万,你的孩子在治疗的时候,生命可能几分钟命就没了,你们的孩子就抱不回湖北了,你们花在多的钱,也是人财两空,医生说:你们有治疗的钱吗?

The results presented in this paper indicated that sodium salt of 3,7-bishemis uccinate of 7-hydroxycholesterol (RS 634) at the dose of 45mg/kg/day (×7,ip) could increase DNA, RNA and protein syntheses in bone marrow cells and protein synthesis in liver,spleen and serum, but no markedly effects on DNA and RNA synthesis in liver and spleen of mice bearing EAC were observed, In the subacute test on rats RS 034 (400mg/kg/day, x30 ip) showed no evident effects on the number of RBC, WBC and the percentage of lym...

本文报告的结果表明7β-羟基胆固醇双琥珀酸单酯钠(RS 024)在有效抗肿瘤剂量下(45mg/kg/day,×7ip)对荷瘤小鼠骨髓细胞DNA、RNA和蛋白质合成有促进作用,对肝、脾的DNA、RNA合成无显著影响,但能促进肝,脾中及血清蛋白质合成。按400mg/kg/day连续给药30天,对大鼠红细胞、白细胞数及淋巴细胞百分率无明显影响。提示该药在有效抗癌剂量下毒性较小,并在一定程度上对免疫功能有增强作用。

Results: From the second days of the operation, the brain swellen overtly. RBC and phagocyte can be seen in the cerebral interstitial space. The adventitia of the brain arteries and the perivascular Virchow ̄Robin space dilated irregularly. The neuronal number of hippocampal CAI sector decreased evidently. In some neuron both the nucleus and cytoplasm condensed, chromatin gathered near the nuclear membrane.

结果: 自术后第二天可见脑组织水肿,红细胞溢出及吞噬细胞浸润,小血管壁外膜及Virchow ̄Robin间隙增宽,内含大量水肿液,海马CAI区正常神经元数量明显下降,且排列及不整齐,细胞皱缩,核固缩、深染,核染色质聚集,核周囊膨大,胶质细胞增生。

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