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小红细胞

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Results True positive rate: immature granulocyte, hemoglobin concentration variation, microcyte, left shift, macrocyte, hypochromic erythrocyte, large platelet, blasts, anisocytosis 86.7%-100.0%, hyperchromic erythrocyte 69.2%, nucleated red blood cell, atypical lymphocyte, platelet clumps

结果 真阳性率:未成熟粒细胞、血红蛋白浓度不等、小红细胞、核左移、大红细胞、低色素性红细胞、大血小板、原幼细胞、红细胞大小不等为86.7%~100.0%,高色素性红细胞为69.2%,有核红细胞、变异淋巴细胞、血小板凝集为13.3%~32.3%;以上所有参数真阴性率为82.8%~100.0%(平均95.0%)。

Red blood cells were imged by AFM and the typical biconcave shapes were observed . The ultrastructure of RBC membrane was also gained. Themorphological changes of red blood cell membrane after the interaction of trichosanthin were clearly observed by AFM.

对红细胞进行成像,观察到红细胞双面凹的典型特征,小范围扫描观察到了红细胞膜表面的超微结构,在此基础上研究了红细胞与天花粉蛋白作用后红细胞膜表面超微结构的变化,并对二者作用的机理进行了分析讨论。

Methods: Rat models of chronic renal failure were made by cut 5/6 kindney or fed with feedingstuff which contains adenine(0.75%) for 4 weeks. Experimental treatment was applied by giving Yi Shen Granule and the curative effect of Yi Shen Granule on ongoing pathological changes of CRF was studied. According to the data of CRF rats in weight, water wastage, hemanalysis(RBC、HGB、HCT、MCV、MCH), urinalysis(volume, specific gravity, pH, proteinuria), blood serum analysis(BUN、Cre、ALB、TP), kidney weight coefficient and kidney morphology ( the grade of expansile renal tubule and the diameter of glomerulus ),the pharmacological effect of Yi Shen Granule could be ascertained.

实验选用0.75%腺嘌呤饲喂法致大鼠慢性肾衰模型和5/6肾切除法致大鼠肾衰模型,考察益肾颗粒对慢性肾功能衰竭进行性病变的影响,以造模动物一般状况观察、血液学指标包括红细胞计数、血红蛋白、红细胞压积、平均红细胞体积、平均红细胞血红蛋白(RBC、HGB、HCT、MCV、MCH),尿液指标(尿量、比重SG、pH值、尿蛋白)、血清生化学指标包括尿素氮、肌酐、白蛋白、总蛋白(BUN、Cre、ALB、TP)、脏器解剖和病理观察指标(肾小管扩张分级评分和肾小球径长)做为判定依据。

Methods:Automated hematologic analyzer was used for platelet count if the URI flag was not due to the effect of microcyte,these samples were also c ounted under light microscope,and the results of these 2 methods were calculated for t test.

用血液分析仪作血小板参数分析,对出现URI报警但又不是小红细胞干扰的标本作显微镜计数,把两法结果作配对t检验。

Results Erythrocyte count, hemoglobin concentration and hematocrit of all the patients with malignant digestive tumor decreased, mean corpuscular volume and mean corpuscular hemoglobin increased, arid there was inconspicuous change in total leukocyte count. The indications of megaloblastic anemia and proliferative anemia in bone marrow hemogram were found in the patients. It was common that the percentage of neutrophils was higher and that of lymphocytes was lower than that of the normal controls.

结果 消化道恶性肿瘤患者的红细胞计数、血红蛋白、红细胞压积均减少,平均红细胞体积、平均红细胞血红蛋白量增高,均表现为巨幼细胞性贫血,骨髓象呈增生性贫血改变,而白细胞总数的变化较小,白细胞分类,中性粒细胞百分比超过正常范围与淋巴细胞百分比低于正常范围者多见,血小板数异常远较血红蛋白与白细胞为少,但36例肝癌患者中28例出现血小板减少。

The cells are plump rods or cocci, surrounded by slime. A multilayered wall may be synthesized around the cell to produce a microcyst resistant to desiccation.

细胞被粘性物质包围,围绕细胞有多层的细胞壁被合成,可以产生小红细胞用来抵抗干燥。

Several parameters (MCV79.6 - 81.8 fl) were normal in 13 cases of microcytosis, red blood parameters test found out that MCV decreased apparently in nuld thalasssemia and RBC increased apparently.

各项检查指标均正常的小红细胞(MCV 79.6~81.8fl)13例,红细胞参数测定结果显示,轻型地贫MCV明显减低,RBC明显增多,与其他小红细胞类型比较差异有统计学意义(P<0.01)。

Results Erythrocyte proportion of measured value of 56.36% and RBCInfo of 53.02% with UF-100 automated urinalysis analyzer .Normocytic rate of 28.52% with Coincidence rate of 100%; Microcytic rate of 16.35% with Coincidence rate of 97.67%; Nonclassifide rate of 55.13% with Coincidence rate of 46.21%.

结果:UF-100尿沉渣分析仪红细胞检出率为56.36%,红细胞信息提示率为53.02%,其中正常红细胞比率占28.52%,与离心沉渣镜检符合率为100%;小红细胞比率占16.35%,与离心沉渣镜检符合率为97.67%;混合红细胞(Non-classifide)比率占55.13%,与离心沉渣镜检符合率为46.21%。

When ethanol goes into the red blood cells, osmotic pressure changing causes the cell vertices moving to the center, and double-concave disc surface will be the spherical one. It results in the red blood cell volume larger and surface area smaller, causes the ratio of the surface area and volume significantly decrease, and the resistance tensile capacity of red blood cells reduced.

分析认为乙醇进入红细胞后,由于渗透压的变化将使细胞顶点向中心移动,双凹形的圆盘曲面将向球形细胞转变,导致红细胞体积变大和表面积的减少,引起红细胞表面积和容积的比值显著变小,红细胞的抗张能力降低。

Results:The results of these 2 methods were(66±17)×109/L and(98 ±2 0)×109/L,their difference was significant(P<0.001).Their influential f actors were large platelets,platelet clumps,cryoglobulins and schistocytes besid es microcytes.

结果:仪器法结果为(66±17)×109/L,而显微镜计数法为(98±20)×10 9/L,两法结果差异有显著性(P<0.001);URI报警时除小红细胞干扰外,还有其他诸多因素;大血小板、血小板凝集块、冷球蛋白、衰老破坏的红细胞碎片等,其中最常见的为大血小板。

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