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The essence of osteonecresis of femoral bead is the etisting uecrosisof bone trabecula and morrow tissue.

在股骨头内,出现不同程度的骨小梁及骨髓组织坏死,是股骨头坏死的本质特征。

MAIN OUTCOME MEASURES:①At week 9, recovery of bone mass was recorded. Height of alveolar bone, density of bone trabecula and osseointegration were observed by X-ray film.

主要观察指标:①种植术后第9周时观察各组骨量的恢复情况、X射线片观察牙槽骨高度、骨小梁致密度及骨整合情况。

Histological analysis showed active bone cell differentiation, proliferation, increased bone trabecula.

组织学分析显示:骨组织呈活跃增殖分化相,骨小梁增加,骨基质深染。

Then glutamate, GABA and GABA_BR1 in cells on bone trabecula surface of distal fermur of rats in every group were checked with immunohistochemistry method.

运用免疫组织化学方法检测各组大鼠远端股骨骨小梁表面细胞的Glu、GABA和GABA_BR1。

Results Compared with model group,the volumes of bone trabecula were increased in both Bushenfugai group and nilestriol group with decreased bone absorbing surface.The bone forming surface and rate of mineralization deposition of nilestriol group were decreased,while there were no significant changes in Bushenfugai group.

结果与模型组比较,补肾富钙中药组和尼尔雌醇组的骨小梁体积显著增加,骨吸收表面减少;尼尔雌醇组的骨形成表面和矿化沉积率下降,但在补肾富钙中药组则无显著变化。

Sp were evaluated by computer-assisted image analysis software, and the content of OPG determined by immunohistochemistry, which included mean optical density 、positive area density in bone trabecula and total positive area of cancellous bone, were evaluated by computer-assisted image analysis and semiquantitative analysis.

Sp,免疫组化方法结合图像分析半定量分析OPG在胫骨的表达,测定平均光密度、OPG在骨小梁中阳性表达的面积密度和OPG在松质骨骨组织阳性表达的总面积。

RESULTS: HE staining showed that bone resorption in Ti treatment group was increased obviously and the structure of bone trabecula was disottlerly and osteoporotic, the volume of osteoclast was enlarged and number was increased. The findings were reduced in etanercep groups, especially in 200 μg/kg group.

结果:苏木精-伊红染色结果为单纯钛处理组骨吸收明显增加,骨小梁结构紊乱及骨质疏松,破骨细胞的形态变大,数目变多;依那西普干预组上述表现减轻,尤以200μg/kg剂量为明显。

Results After treatment, IOP was descended and trabecula interspace was wider than the control eye. The expression of collagen Ⅰ, laminin and fibronectin was inhibited.

结果 低强度超声处理后眼压显著下降,小梁网间隙增大,胶原Ⅰ、层黏连蛋白及纤维连接蛋白的表达低于对照组。

Histology showed that control group had massive cartilage cell gathering together and bone trabecula disturbance, it had no significant bone cortex and medullary cavity formation.

组织学检查显示:对照组中可见大量团聚软骨细胞、骨小梁紊乱,无明显骨皮质、髓腔形成。

It was revealed by scanning electron microscopy that the bone trabecula of model group was thin,interrupted and sparsate,while those were improved in both Bushenfugai group and nilestriol group.

扫描电镜观察显示,模型组骨小梁变细、中断、排列稀疏,而补肾富钙中药组和尼尔雌醇组上述变化较轻微。

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