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Objetive:To investigate the histopathological features and detect the mutation of JAK2V617F in PV、ET and IMF;to analyze the effects of the stages of myelofibrosis and the mutation on the number of leucocyte in PV and ET patients;Methods: the morphological features of 69 patients who dignosed in the first time were studied by HGF and Gomori stains ; the mutation of JAK2V617F was detected in 38 blood or marrow samples of PV、ET and IMF patients by real-time PCR;the effects of the stages of myelofibrosis and the mutation on leucocytes were analyzed;Results: Different stages of reticulin were observed in 15 PV and 15 ET patiens'marrow sections,and the cytosis、the pleomorphism and the bone trabecula side location of megakaryocytes were observed in all PV、ET and IMF patients;the means of leucocyte in patients with and without JAK2V617F were 20.4×109/Land 11.4×109/L respectively;the P value was 0.367 as comparing the leucocytes among different stages of reticulin increasing.

目的:探讨PV、ET、IMF患者的骨髓病理特点并且检测JAK2V617F突变的发生率,分析骨髓中纤维增生程度以及JAK2V617F对PV、ET患者白细胞数的影响;方法:69例初诊患者的骨髓切片经HGF染色以及Gomori染色后进行形态学研究;并利用real-time PCR法测38例患者的骨髓或者外周血的JAK2V617F突变;分析骨髓切片中纤维组织增生程度以及JAK2突变对患者白细胞数的影响;结果:15例PV和15例ET患者的骨髓切片中可以观察到不同程度的纤维组织增生,所有PV、ET、IMF患者骨髓病理中可见到巨核细胞增多、巨核细胞多形性改变以及巨核细胞定位于骨小梁旁;12例PV、4例ET、4例IMF中检测到JAK2V617F;有突变和无突变患者发病时白细胞数均值分别为20.4×109/L和11.4×109/L,比较不同纤维增生程度的PV、ET患者的白细胞数均值,P值为0.367。

In retrobulbar anesthesia group, there were higher rates of complicatio...

表面麻醉是青光眼小梁切除术一种安全有效的麻醉方法,临床上值得应用与推广。

Four patients had retrobular hemorrhage and one patient vision lose in retrobulbar anesthesia group.

球结膜下麻醉对于青光眼小梁切除是一种安全有效、并发症少的麻醉方法,值得推广。

As regards to age,gender andhistopathological characters,the 33 cases were as follows:①age,27-67years old(Median 45 years old);②gender,28 males and 5 females;③themaximum diameter of lesions,1.0-12.5cm(Mean5.9cm);④the histology,trabecular type 18 cases(18/33,54.5%),pseudoglandular 4(4/33,12.1%),compact 7(7/33,21.2%)and scirrhous 4(4/33,12.1%);⑤Edmondson-Steiner classification,gradeⅠ3 cases(3/33,9.1%),Ⅱ14(14/33,42.2%),Ⅲ 12(12/33,36.4%)and Ⅳ 4(4/33,12.1%).

年龄、性别及组织病理学方面结果如下:①年龄,27-67岁(Median 45岁);②性别,男性28例,女性5例;③肿块最大径,1.0-12.5cm(Mean5.9cm);④组织学类型,小梁型18例(18/33,54.5%),假腺管型4例(4/33,12.1%),致密型7例(7/33,21.2%)及硬化型4例(4/33,12.1%);⑤Edmondson-Steiner分级,Ⅰ级3例(3/33,9.1%),Ⅱ级14例(14/33,42.2%),Ⅲ级12例(12/33,36.4%)及Ⅳ级4例(4/33,12.1%)。

Objective To discuss the effect of scleral concave pool trabeculectomy in combination with MMC and Healon on primary glaucoma.

目的探讨丝裂霉素C和透明质酸钠在巩膜潜池式小梁切除术治疗青光眼中的作用。

AIM: To discuss the penetrating trabeculectomy procedures for glaucoma using a sclerocorneal tunnel.

目的:讨论经角膜巩膜隧道所行的穿透性小梁切除术治疗青光眼。

METHODS: Recent studies of different authors reported on five surgical variations of the sclerocorneal tunnel approach without radial incisions.

最近有学者报道了五种不同类型的经角膜巩膜隧道小梁切除术,术中不需行放射状巩膜切开。

Trabeculectomy ; sclerocorneal funnel ; radial incision ; glaucoma

小梁切除术;青光眼;角巩膜隧道;放射状切口

Immuhnoreactive nerve fibers were not found in the speen trabecula.

人脾脏小梁中未查见免疫反应神经纤维。

It was ciliary body edema, ciliary body detachment, choroids detachment, subchoroid hemorrhage and following changes of trabecular meshwork that was the principal mechanism of secondary glaucoma after SEO.

睫状体水肿、脱离、脉络膜脱离、由此继发的前房和小梁网的改变是兔眼巩膜环扎术后继发性青光眼的主要机制。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。