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(1) The input of the internal fixation implant should be in accordance with the compressive trabeculae and be clingy with the femoral calcar, Abduction in small degree (10-30°) will improve the stress in femoral neck region. The stress distribution of the femur under extemal violence explained why the old people are easy to get the middle and low part fractures of the femoral neck and intertrochanteric fractures.(2) The finite element model of femoral neck fracture is good in orrowing various fixation methods for femoral neck fracture.

(1)三维有限元方法用于研究不规则物体是一种有效、准确的数值方法,不仅能考虑到所研究物体的几何形状,而且也考虑到物体的内部结构特性;股骨颈处的压力骨小梁和股骨距是重要的承载结构,内固定物的放置应循压力骨小梁方向尽量紧贴股骨距钻入;载荷主要通过压力骨小梁和股骨距传导至股骨干的中下1/3处;一定角度的下肢外展(10-30°)会较明显的增加股骨颈区的应力,而下肢的内收反而会减小此区的应力;暴力作用时股骨上端应力分布特点从生物力学角度说明老年人易于发生股骨颈中下段骨折和转子间骨折的原因。

Result:As compared with the model group, the effect of small dose group and middle dose group of osteopractic total flavone on TBV% of shankbone increased significantly; the effect of small dose group and middle dose group of osteopractic total flavone on TRS% of shankbone reduced significantly and TFS%, AFS%, MAR, BFR of shankbone reduced obviously; the effect of middle dose group of osteopractic total flavone on OSW and mAR reduced obviously, the effect of small dose group of osteopractic total flavone on them had the tendency of reducing, but there was no statistical significance.

结果 :对胫骨骨小梁体积百分比的影响,与模型组比较,骨碎补总黄酮小剂量组和中剂量组的TBV %明显增高;对胫骨骨小梁吸收表面百分比的影响,与模型组比较,骨碎补总黄酮小剂量组、中剂量组的TRS %显著降低;对胫骨骨小梁形成表面百分比,活性生成表面百分比,骨小梁矿化率和骨小梁骨生成率的影响,骨碎补总黄酮小剂量组、中剂量组的TFS %,AFS %,MAR ,BFR较模型组皆明显降低;对胫骨类骨质平均宽度和骨皮质矿化率的影响,骨碎补总黄酮中剂量组的OSW和mAR与模型组比较,明显降低;骨碎补总黄酮小剂量组与之相比,有下降的趋势,但无统计学意义。

The lumbar were cut and stined with Masson Golder Trichrome for bone histomorphomemetric analysis. Result: The QiangGuYin group ovariectomized rats' in 1.5m, 4.5m, 6m, Tb. Th compared with Fosamax group with statistical significance; in 4. 5m, 6m, compared with control group in Tb. sp with statistical significance.

结果:强骨饮组1.5月、4.5月、6月骨小梁厚度与福善美组数据相比具有统计学意义,4.5月,6月骨小梁间距与福善美组相比具有统计学意义,强骨饮组和福善美组数据与空白组相比骨体积分数、骨小梁厚度、骨小梁间距都具有统计学意义。

Microscope examination:in group A,at 2 weeks,a few inflamatory cells appeared in the holes with many osteoblasts and ostoid appeared around the drilled holes.At 8 weeks,marrow formed in the drilled holes in group B,at 2 weeks,there were a large amount of osteoblasts in the drilled holes and some ostoid formed around thc drilled holes.At 4 weeks,the drilled holes were full of trabeculae.At 8 weeks,the trabeculae matured with the marrow appeared in the intertrabecular space.

组织学结果:2周时A组钻孔区出现少许炎症细胞,边缘出现较多成骨细胞并有骨组织形成,至8周时,钻孔区内形成骨髓组织,只在边缘形成骨小梁结构。2周时B组钻孔区有大量的成骨细胞,边缘有较多骨组织形成,4周时钻孔区内充满重生骨小梁结构,8周时钻孔区内骨小梁成熟,小梁有骨髓组织填充。

Microscope examination:in group a,at 2 weeks,a few inflamatory cells appeared in the holes with many osteoblasts and ostoid appeared around the drilled holes.at 8 weeks,marrow formed in the drilled holes in group b,at 2 weeks,there were a large amount of osteoblasts in the drilled holes and some ostoid formed around thc drilled holes.at 4 weeks,the drilled holes were full of trabeculae.at 8 weeks,the trabeculae matured with the marrow appeared in the intertrabecular space.

组织学结果:2周时a组钻孔区出现少许炎症细胞,边缘出现较多成骨细胞并有骨组织形成,至8周时,钻孔区内形成骨髓组织,只在边缘形成骨小梁结构。2周时b组钻孔区有大量的成骨细胞,边缘有较多骨组织形成,4周时钻孔区内充满新生骨小梁结构,8周时钻孔区内骨小梁成熟,小梁有骨髓组织填充。[结论]骨髓基质干细胞对兔股骨头缺血性坏死有良好的修复作用。

Results Microstructure of callus showed that the area of mature trabecular in callus of OPFM group was smaller than that of CFM group, and was thinner with a wide intertrabecular distance. The dynamic parameters demonstrated that the fluorescent labeling percentage on the trabecular surface of OPFM group was lower than that of CFM group, but bone mineral apposition rate was higher.

结果 ①骨痂组织骨组织形态计量学结果发现:OPFM组成熟小梁骨占骨痂面积比CFM组小,且小梁骨厚度变薄、小梁骨间距较宽;同时骨小梁动力学参数显示:OPFM组骨小梁表面荧光标记百分比较CFM组低,而骨矿化沉积率却较高。

Exercise with above proper intensity has bad effect on the development of bone tissue morphous.

3适宜强度的负重游泳运动对生长发育期大鼠骨组织形态中骨小梁面积百分数骨小梁厚度、骨小梁数量和骨小梁分离度;结构力学中的载荷和桡度均有良好的效果。

Results: All 8 patients with INVM showed prominent excessive myocardial trabeculation and deep intrabecular. Endocardium of 25 patients with IDCM were smooth, except 2 patients, in which one had excessive myocardial trabeculations in beast apex, the other in lateral wall.

结果:8例INVM均有粗大的肌小梁小梁间深陷的陷窝,25例IDCM 23例均未见粗大肌小梁及陷窝,1例在心尖部见轻度增粗的肌小梁,另1例在左室侧壁见数目有限的增粗肌小梁,并见其与假腱索相连。

Results After 3 months of kidney radiation by 15 Gy of Cs137 γ-rays, the changes with kidney shrank, Bowman's capsules straitened or disappeared, glomerular swelled, some epithelia denaturalized or died were observed. Mitochondria tumefied and the cristae shortened, lessened and disordered. Urine β2-MP rose evidently. It was lowered significantly the renal 25-OH-D-1α-hydroxylase activity and its mRNA expression. The dry and ash weight, BMD of femur and lumbar were significantly reduced, volume and width of bone trabecula were distinctly decreased and the space increased in model group. The Pyd / Cr increased and ALP decreased as well.

结果 15Gy 137Cs-γ射线肾局部照射3个月后肾脏体积缩小,肾小球肿大,Bowman氏囊囊腔狭窄甚至消失,部分肾小管上皮细胞变性、坏死,线粒体肿胀,体积增大,线粒体嵴变短、减少、排列紊乱;尿β2-MP显著增加;肾1α羟化酶活性及1α羟化酶mRNA基因表达量明显下降;肾辐射组股骨干重、灰重、腰椎和股骨BMD明显降低;骨小梁体积和骨小梁宽度减少,骨小梁间距增加,MAR减小;腰椎压缩和股骨三点弯最大载荷明显降低,Pyd / Cr值明显增加,ALP显著降低。

The data of femur biodymamics showed that acupuncture and moxibustion could increase the biggest load, modulus of elasticity, the biggest flexibility. The data of shank bone morphometry showed that acupuncture and moxibustion could increase percentage of bone trabecula bulk, lessen percentage of bone trabecula absorption and restoration, slow the rate of bone trabecula mineralization. Slices indicated that the structure of bone trabecula became basically complete.

股骨骨生物力学参数显示,针灸可提高OP症大鼠股骨最大载荷、弹性模量和最大挠度;胫骨骨组织形态计量学指标显示,针灸可增加骨小梁体积百分比,减少骨小梁吸收表面百分比和骨小梁形成表面百分比,降低骨小梁矿化沉积速率;胫骨骨组织切片显示,针灸后大鼠骨小梁结构已基本完整。

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