小核

In group B, a large amount of inflammatory cell infiltration in liver tissues were noted and hepatic cells showed spotty necrosis and bleeding under the light microscope; the electron microscope showed a significant decrease of mitochondria cristae, the broadness of endoplasmic reticula, hepatic cell necrosis and karyopyknosis.

B组光镜下可见肝组织大量炎性细胞浸润，肝细胞点状坏死及出血；电镜下可见线粒体嵴明显减少，内质网扩张，出现凋亡小体及核固缩。C组上述病理变化明显减轻。

Result 1 Magnetic nanoparticles, magnetic nanoparticles modified with antisense oligodeoxynucleotide of human telomerase reverse transcriptase induced HL-60 tumor cells to apoptosis, we could see typical morphologic change of apoptosis cells: karyopyknosis, chromation"s condensing and aggregation in nuclear, forming crescent-shaped or annulus structures to lean on edge of cell nucleus"s membrane and posing apoptosis body by Atomic Force Microscope, Fluorescence microscope, transmission electron Microscope 2 There was a significant difference compared with control group(p.01), inhibition ratio had significant positive correlation with medication dosage and time ;during 0.8-8μM dosage amplitude, inhibition ratio accrescenced by dosages increasing. However, the inhibition ratio would decrease when dosage over 8-80μM.

结果 1 磁性纳米粒子、修饰有端粒酶反义寡核苷酸的磁性纳米粒子诱导HL-60细胞发生凋亡，原子力显微镜、光学显微镜、荧光显微镜和透射电镜下均观察到HL-60细胞呈现典型的凋亡细胞的形态变化：细胞核固缩，核内染色质浓缩、凝聚、形成新月形或环状结构紧靠在细胞核膜边缘，并形成凋亡小体。2 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子对HL-60肿瘤细胞的生长和增殖有明显的抑制作用，与对照组相比有显著性差异(p＜0.01)，在剂量为0.8-8μmol／L范围内，抑制率随剂量的增加而增加，当剂量超过8μmol／L时，抑制率反而下降；3 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子可增强p53基因的表达活性，引起DNA降解损伤，反向调节细胞周期活动，促使细胞从G0期进入G1期，抑制肿瘤细胞的生长。4 修饰有端粒酶反义寡聚脱氧核苷酸的量子点能通过内吞作用进入HL-60肿瘤细胞的细胞核，可以在细胞内进行定位和促进HL-60肿瘤细胞的凋亡。

Typical characteristics of apoptotic cells as membrane blebbing, chromatin pyknosis, karyorrhexis, and apoptotic body were seen under electromicroscope. Apoptosisspecific DNA ladder bands from SGC-7901 cells were visualized with electrophoresis. Hypodiploid apoptotic peak was observed before G1 phase by flow cytometry analysis.

凋亡细胞形态学上表现为细胞膜起泡、染色质固缩、核碎裂、凋亡小体形成；DNA电泳呈现凋亡特征性阶梯状条带；流式细胞仪分析显示G1期前出现亚二倍体凋亡峰。

A 30 min exposure to peroxynitrite (10〓μmol/L) followed by incubation in fresh medium induced apoptosis in cultured cerebellar granule cells, which was confirmed by DNA laddering, chromatin condensation, nuclei fragmentation, and the formation of apoptotic bodies.

原代小脑颗粒细胞经10μmol/L过氧化亚硝基处理30min，并继续培养一定时间后逐渐发生细胞凋亡，主要表现为DNA链断裂、染色质凝缩、核破裂、形成凋亡小体。

Refers to Down's syndrome (Down's syndrome, dementia-like伸舌) screening, that is, pumping blood or amniotic fluid do villus cells, and then do Karyotype analysis, such as the emergence of 21 - trisomy map, you can diagnose fetus for Down syndrome. 2, AFP Chinese name for the AFP, such as maternal and fetal amniotic fluid were increased AFP confirmed fetal neural tube defects, namely spina bifida, spinal Meningocele, no brains infants, microcephaly, hydrocephalus.

是指唐氏综合症的筛查，就是抽绒毛血或羊水做细胞培养，然后做染色体核型分析，如出现21-三体综合征图谱，即可诊断胎儿为唐氏综合征。2、AFP中文名称为甲胎蛋白，如母血及胎儿羊水AFP均增高，证实胎儿有神经管畸形，即脊柱裂、脊脑膜膨出、无脑儿、小头畸形、脑积水。

Nucleared blood cells, cells of glomerulus and mesonephric tubule express multiple growth factors and their receptors.

人胚中肾内的有核血细胞、肾小管内皮细胞、肾小囊和肾小球细胞表达多种生长因子。

Positioning is examined by using micrococcal nuclease to examine cleavage sites relative to a restriction site at the 5 end of the gene.

最初基因会展现一个核小体的模型，它是由穿过基因一段有效距离的启动子构成的；在3ˊ端范围中定位作用遗失。

Results The micronuclear rates of polychromatic erythrocytes in mice with pine and maple paring exposure were similar to those in negative control group, but significantly lower than those in positive control group.

结果 以松木刨花及枫木刨花水提取物染毒的各组小白鼠的微核率与阳性对照组比较差异有统计学意义(P0.05)。

In order to better understand their phylogenetic relationship and identify the uncertain species, the sequences of the small subunit ribosomal RNA (ssurRNA, 16 S rRNA) genes of nine microsporidia infectious to the silkworm, Bombyx mori, were determined.

微孢子虫是真核生物，但其核糖体及核糖体RNA为原核生物型。为探讨9种家蚕病原性微孢子虫的种属地位及亲缘关系，对已广泛用於生物进化分类的核糖体小亚单位RNA基因进行了研究。

Particle aroused the many in suspension in microtherm general air to form low coagulate nucleus, make the little water all round its condenses Cheng Bing.

低温将空气中大量的悬浮微粒激发起来形成了低凝核，并使其四周的小水滴凝聚成冰。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。