小核

Core particles ) Particles resulting from micrococcal nuclease digestion of nucleosomes, consisting of 140-bp DNA and the histone octamer of a nucleosome.

在真核生物中，双螺旋的 DNA 分子围绕一蛋白质八聚体进行盘绕，从而形成特殊的串珠状结构，称为核小体。

Karyotypic findings showed that all cultivars were mixoploid with chromosome number ranging from 49 to 57, and 54 was the most frequent number observed.

结果表明：（1）17个栽培小菊均为混倍体，染色体数在49～57之间变异，以54条为主；（2）染色体呈现多态性：多数品种由中部、近中部和近端部着丝粒染色体组成；最长与最短染色体的比值为1.62～2.39；臂比＞2的染色体所占的比率为11.11%～29.62%；核型不对称系数为59.74%～63.37%；3个地被菊品种和'奥运橙光'、'金陵白凤'（2n=53）核型类型为&2B&，其它品种为&2A&型。

Results: At the concentrations of 0.1, 1 and 10 μmol/L, berberine dose-dependently suppressed the formation of TRAP-positive multinucleated cells, the TRAP activity and the osteoclastic bone resorption. The strongest inhibitory effect was exhibited at the concentration of 10 μmol/L, with the inhibiting rate of 60.45%, 42.12% and 72.69% respectively.

结果：小檗碱在0.1~10μmol/L范围内，浓度依赖性地抑制TRAP阳性多核破骨细胞的形成和TRAP活性，减少破骨性骨吸收陷窝的面积；在10μmol/L浓度下，对破骨细胞的抑制作用最强，对TRAP阳性多核破骨细胞的形成和TRAP活性的抑制率分别达到了60.45%和42.12%，骨吸收陷窝面积减少72.69%。

Megakaryocytes in fetal liver and bone marrow are small sized during ontogenesis and remain so until a few months after delivery .

在胚胎发育时期，无论是胎肝造血还是骨髓造血，巨核细胞形态均较小，直到出生后几个月，仍小于成人的巨核细胞。

At mononucleus microspore stage,cytoplasm were thick and organella,such as mitochondria,endoplasmic reticulum were abundant.At two\|nucleus and three\|nucleus stage,there were a lot of starch grains.

结果表明，85 EA、89 AR、TA 与恢复系杂交F1 代小孢子发育表现出明显的可育特征：在单核期，细胞质浓，细胞器丰富，线粒体、内质网等十分发达，二核及三核期淀粉粒数量多。

Antoni type A areas consist of compact spindle-shaped cells with twisted nuclei and indistinct cytoplasmic borders. They are arranged in interlacing fascicles with nuclear palisading, whirling, and Verocay bodies.

Antoni A型区的细胞呈梭形，胞核扭曲，胞质边界模糊，细胞排列为呈束状交错或旋涡状，胞核呈栅栏状，有Verocay小体。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

The results show that if the initial crystal nucleus is not melted, its size has nothing to do with the simulation results. With the coefficient of interfacial anisotropic strength increasing, the dendritic tip's growing speed increases linearly, while its radius decreases parabolically. The lower the sub-cooling degree is, the more difficult it is to find secondary dendrites.

结果表明：在保证初始晶核不被熔化的前提下，初始晶核半径r0的大小不影响模拟结果；随着界面各向异性系数的增大，枝晶尖端生长速度以线性方式增大，而枝晶尖端半径以抛物线方式减小；过冷度越小，枝晶的生长越困难，越不能出现二次枝晶。

Most of the a-sexual embryo sacs also parthenogenetically developed into asexual seeds,which is the same as that of their maternal parent.

此外，平邑甜茶也形成次生极核，并在卵分裂前，形成胚乳游离核；而卵的发育，无论受精与否都要经过3-5天休眠后分裂，并逐渐形成小球形胚、子叶胚。

One has to search and count mitotic figures carefully in better preserved areas, and look for the other atypical features - hypercellularity, small cells with high nucleocytoplasmic ratios, patternless growth, and brain parenchymal invasion.

应该在保存好的区域仔细寻找计数核分裂，寻找其它非典型特征：细胞密集、核浆比高的小细胞、无序生长方式、脑实质浸润。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。