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小支气管

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The simultaneity use of Xiao Er Chuan Ke Ye and Cang Er Zi San intervening asthma and allergic rhinitis,comparing simply use Xiao Er Chuan Ke Ye,has the predominance in prolonging time of introducing asthma and reducing the frequency of nodding breathe,which indicated that the treatment of allergic rhinitis has great importance in asthma control and lessen the degree of asthma(frequency of rat nodding breath).3,The combination high-dose group has better therapeutic effect than dexamethasone group,all Chuan Ke Ye groups and combination low,medium group in the prevention and control of allergic rhinitis symptoms,reduced airway hyper responsiveness,while in improving breath difficulties combination high-dose group has similar effect with western medicine group,and better effect than all Chuan Ke Ye groups and combination low,medium group.Its efficacy increased with the prolonging of treatment time,but fewer side effects,which makes the application safer and more reliable.4,Xiao Er Chuan Ke Ye combining with Cang Er Zi San can obviously improve the pathological changes in rats with bronchial airway remodeling,reducing the serum TGF-β1,IL-4,ECP levels,increasing the level of serum IFN-γand the imbalance IFN-γ/ IL-4 ratio.

而运用小儿喘咳液合苍耳子散同时干预哮喘与过敏性鼻炎,较之单纯使用小儿喘咳液治疗哮喘,其在延长引喘时间、减少点头呼吸频度等方面有明显的优势,说明过敏性鼻炎的治疗,对于控制哮喘发生,减轻哮喘发作的程度,有着重要的意义。3、大剂量的合方在预防和控制过敏性鼻炎症状、降低哮喘气道高反应性方面疗效较地塞米松对照组、喘咳液各剂量组及合方小、中剂量组更优,而改善呼吸困难方面则与西药组相当,优于喘咳液各剂量组及合方小、中剂量组,且其疗效随着治疗时间的延长而增加,但副作用更少,使用更加安全可靠。4、小儿喘咳液合苍耳子散能明显改善气道重塑大鼠支气管的病理改变,同时降低血清TGF-β1、IL-4、ECP水平,提高血清IFN-γ水平及失衡的IFN-γ/IL-4比值。

The ratio of cell proliferation to apoptosis in lungs of COPD group was increased significantly by 4 folds compared with controls. In lungs of COPD group, proliferative cells mainly localized in small palmary vascular walls, but Apoptotic cells was less in small pulmonary vascular walls.

COPD组肺内,增殖阳性细胞主要位于肺小血管壁,另有一些位于支气管壁;凋亡细胞在COPD组肺小血管壁上较少见。

Within the lungs, the bronchi continue dividing into smaller tubules, the smallest of which is called the alveoli.

在肺部,支气管,继续划分成较小的小管,最小的是被称为肺泡。

Results showed:(1) The airway responsiveness of smoke control group was higher than that of normal control group, the airway responsiveness of smoke + exercise group was lower than that of smoke control group;(2) Plasma level of cortisol determined immediately after exercise was higher than that determined before exercise, no significant difference occurs between that determined next day morning after all exercise finished in contrast to that determined before exercise;(3) HE staining showed, there was severe chronic pulmonary inflammatory response in smoke control group, which was reduced in the smoke + exercise group;(4) chronic cigarette smoke downregulated the protein and mRNA expression of BKca in smooth muscles of bronchi and bronchioli, exercise increased the mRNA expression of BKca;(5) chronic cigarette smoke downregulated the protein and mRNA expression of Kv1. 5 in smooth muscles of bronchi and bronchioli, exercise increased both the protein and mRNA expression of Kv1. 5 in contrast to smoke control group in bronchioli and did not effect the expression of Kv1. 5 in bronchi;(6) chronic cigarette smoke induced upregulation of FIZZ1/RELMα in bronchial smooth muscle cells, exercise decreased these effect.

结果:(1)吸烟对照组的气道反应性明显增高,吸烟加运动应激可明显降低大鼠的气道反应性;(2)吸烟运动组运动后血浆皮质醇浓度明显高于运动前,但全部运动结束后次日晨测定的血浆皮质醇浓度与运动前无明显差异;(3)HE染色显示,吸烟对照组肺组织出现明显的慢性炎症反应,吸烟加运动应激组比吸烟对照组炎症反应轻;(4)慢性吸烟可降低大鼠大气道和小气道BKca mRNA和蛋白表达,而吸烟加运动应激可使BKca mRNA表达上调,但对小气道的蛋白表达无影响;(5)慢性吸烟可降低大鼠大气道和小气道Kv1.5蛋白和mRNA表达,在小气道吸烟加运动应激可减轻这种作用,大气道则无作用;(6)吸烟使支气管平滑肌的FIZZ1/RELMα蛋白表达明显增强,而吸烟加运动组的RELMα蛋白及mRNA均明显减弱。

RESULTS: As compared with group I-R, Fas/FasL mRNA slightly expressed in intima and extima of small pulmonary artery, alveoli, and bronchiole epithelia in group Pur. The values of AI, W/D and IQA showed significantly lower than that in group I-R at 60, 180, 300 minutes after reperfusion in lung tissue (P.01 and P.05). Meanwhile, abnormal changes of the lung tissue in morphologically were lessen markedly in group Pur.

结果:肺再灌注1h、3h、5h, Pur组Fas/FasL mRNA在肺小动脉内膜、肺小静脉内膜、肺泡上皮及肺支气管上皮呈弱阳性表达,明显低于同一时点I-R组(P.05);AI、W/D和IQA值显著低于I-R组(P.01和P.05);肺组织形态学异常改变不同程度减轻。

Bronchiolitis obliterans is the most disturbing complication following lung transplantation. This study is to investigate whether prolonged ischemia would promote early establishment of BO Material and Methods Left lower lobectomy was performed from miniature swine. Lung fragments, each measured 1 cm3, contained terminal bronchioles were auto- or alloimplanted into the subcutaneous area around the nipples. These lung implants were removed on 7th; 14 th; 21 th; 28th and 56th days and were fixed for histological examination. Experimental group using the same procedures but the left lower lobe was washed with 4.degree.C Lactate ringer via interlobar artery before lobar bronchus was resected.

肺移植后的阻塞性细支气管炎是肺移植后最困扰的并发症,本研究的目的希望了解缺血时间的延长是否会促进阻塞性细支气管炎提早发生实验方法施行小猪的左下肺叶切除手术,将取下的肺切成含终末支气管1 公分立方的肺小块,以自体及异体异位肺移植模式,将植入小猪皮下的肺小块於植入后第7、14、21、28 及56 天取下,在病理下检示其病理变化,并利用原位灌留的方式将左下肺叶以4℃林格氏液灌洗后再摘除之,观察有无灌洗对於阻塞性细支气管炎生成的影响。

My research tries to find the variational characteristics of the lung cancer patients'sublingual venae, which can be use as the basis for general investigations of highly dangerous people, and diagnose and treat lung cancer patients in the early stage. It will be play an important role in improving the level of peoples'health.

将研究对象分为4组,观察组选择经病理学检查或细胞学检查确诊的152例原发性支气管肺癌患者,其中男88例,女64例,平均年龄60.04±11.98岁,临床分期Ⅰ期32例,Ⅱ期26例,Ⅲ期52例,Ⅳ期42例,经病理确诊的共81人,其中非小细胞肺癌66例,小细胞肺癌15例。

Results show that aqueous solution (7. 35mg/mL) of saponins markedly prolongs the latent period of cough induced by ammonia liquor, increases the secretion of phenol red from the trachea in mice and decreases mice's activity strength and frequency.

结果表明:7.35 mg/mL百合皂苷液能显著地增加小白鼠支气管对酚红的排泌量,具有显著祛痰作用,对氨水引咳的小白鼠具有显著的镇咳作用,对小白鼠具有极显著的镇静作用。

Results rolls the massive sphere focus of infection altogether 25 examples (9 examples to have "crecent moon to draft", 8 examples have "air bronchial tube to draft", 5 example edges have "burr to draft", 3 examples have "corona to draft").the double lung spot punctual subtotal nodular focus of infection altogether 15 examples, in 13 example tubercle shade the small cavity, the pulmonary abscess type changes the l example obviously.big laminated consolidation 3 examples.the mediastinum lymph node increases the partner chest cavity or the pericardium accumulates the fluid l example.

结果:团块状球形病灶共25例(其中9例有&新月征&,8例有&空气支气管征&,5例边缘有&毛刺征&,3例有&晕征&)。两肺斑点状小结节状病灶共15例、其中13例结节影内可见小空洞,肺脓肿样改变1例,大片状实变3例。纵隔淋巴结增大伴胸腔或心包积液1例。

this gets sick the clinical symptom not to have the characteristic value, the medical history has the reference value.the sphere focus of infection has the crecent moon in the phantom performance to draft, the air bronchial tube drafts, the corona drafts to this sickness has the prompt value, sends the tubercle to see the small empty shade to have the diagnosis value, if in the discovery meniscus cavity has along with the body posture change "in the hole the ball drafts", has the important diagnosis value to the lung aspergillomycosis.this gets sick the diagnosis needs the pathology and the bacteriology inspection.

本病临床症状无特征性,病史有参考价值。在影像表现上球形病灶有新月征、空气支气管征、晕征对本病有提示价值,多发小结节均见小空洞影有诊断价值,如发现半月形空洞内有随体位改变的&洞中球征&,对肺曲菌病有重要诊断价值。本病的确诊需病理和细菌学检查。

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