小体

In group B, a large amount of inflammatory cell infiltration in liver tissues were noted and hepatic cells showed spotty necrosis and bleeding under the light microscope; the electron microscope showed a significant decrease of mitochondria cristae, the broadness of endoplasmic reticula, hepatic cell necrosis and karyopyknosis.

B组光镜下可见肝组织大量炎性细胞浸润，肝细胞点状坏死及出血；电镜下可见线粒体嵴明显减少，内质网扩张，出现凋亡小体及核固缩。C组上述病理变化明显减轻。

Result 1 Magnetic nanoparticles, magnetic nanoparticles modified with antisense oligodeoxynucleotide of human telomerase reverse transcriptase induced HL-60 tumor cells to apoptosis, we could see typical morphologic change of apoptosis cells: karyopyknosis, chromation"s condensing and aggregation in nuclear, forming crescent-shaped or annulus structures to lean on edge of cell nucleus"s membrane and posing apoptosis body by Atomic Force Microscope, Fluorescence microscope, transmission electron Microscope 2 There was a significant difference compared with control group(p.01), inhibition ratio had significant positive correlation with medication dosage and time ;during 0.8-8μM dosage amplitude, inhibition ratio accrescenced by dosages increasing. However, the inhibition ratio would decrease when dosage over 8-80μM.

结果 1 磁性纳米粒子、修饰有端粒酶反义寡核苷酸的磁性纳米粒子诱导HL-60细胞发生凋亡，原子力显微镜、光学显微镜、荧光显微镜和透射电镜下均观察到HL-60细胞呈现典型的凋亡细胞的形态变化：细胞核固缩，核内染色质浓缩、凝聚、形成新月形或环状结构紧靠在细胞核膜边缘，并形成凋亡小体。2 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子对HL-60肿瘤细胞的生长和增殖有明显的抑制作用，与对照组相比有显著性差异(p＜0.01)，在剂量为0.8-8μmol／L范围内，抑制率随剂量的增加而增加，当剂量超过8μmol／L时，抑制率反而下降；3 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子可增强p53基因的表达活性，引起DNA降解损伤，反向调节细胞周期活动，促使细胞从G0期进入G1期，抑制肿瘤细胞的生长。4 修饰有端粒酶反义寡聚脱氧核苷酸的量子点能通过内吞作用进入HL-60肿瘤细胞的细胞核，可以在细胞内进行定位和促进HL-60肿瘤细胞的凋亡。

Its characteristic changes are monocellular occurrence,pyknosis,karyorrhexis and the formation of apoptotic body.

其特点是单细胞发生，胞核浓缩、碎裂，核碎块被胞膜包裹，形成特异性的&凋亡小体&；细胞器多以萎缩变化为主。

Results: observed typical changes of apoptosis(chromosome condensation, karyorrhexis, apoptotic body ) by TEM and Fluorescence microscopy. The number of apoptosis was increased with elevation of LPS concentration under the microscope.

结果 Hoechst荧光染色及电镜观察到脂多糖处理后滋养细胞染色体浓缩，细胞核裂解，见凋亡小体等典型凋亡表现，镜下随着脂多糖浓度的增加凋亡细胞数量显著增加。

Results HE staining showed that sulindac could inhibit the growth of tumor cells, with the morphological presentations as apoptosis and necrosis including pyknosis, karyorrhexis and chromatin crescent formation, etc. By electron microscopy, cells also had apoptotic characteristics including chromatin crescent formation and apoptotic body. Immunohistochemistry and Western-blot assay results showed that 48 hours after sulindac administration, the expression of NF-κB, bcl-2 and bax gradually decreased, while the level of bax protein gradually increased, in a dose dependence manner.

结果 苏木精－伊红染色检测结果显示舒林酸抑制肿瘤细胞生长，肿瘤细胞出现核固缩、核碎裂、染色质边集等凋亡及坏死的形态学表现；电镜下可看到染色质边集、凋亡小体；免疫组化、Western-blot结果显示舒林酸作用48 h后人胃癌SGC-7901细胞NF-κB、bcl-2表达逐渐下降，bax表达逐渐上升，具有剂量依赖性。

A 30 min exposure to peroxynitrite (10〓μmol/L) followed by incubation in fresh medium induced apoptosis in cultured cerebellar granule cells, which was confirmed by DNA laddering, chromatin condensation, nuclei fragmentation, and the formation of apoptotic bodies.

原代小脑颗粒细胞经10μmol/L过氧化亚硝基处理30min，并继续培养一定时间后逐渐发生细胞凋亡，主要表现为DNA链断裂、染色质凝缩、核破裂、形成凋亡小体。

Methods The percentages of apoptotic bodies and the DNA lytic rates in mouse thymocytes and splenocytes were detected with flow cytometry and fluorospectrophotometry, respectively.

采用流式细胞术和荧光分光光度法分别检测小鼠胸腺和脾淋巴细胞凋亡小体百分率和DNA裂解率。

Positioning is examined by using micrococcal nuclease to examine cleavage sites relative to a restriction site at the 5 end of the gene.

最初基因会展现一个核小体的模型，它是由穿过基因一段有效距离的启动子构成的；在3ˊ端范围中定位作用遗失。

The morphologic changes of these three tissues were observed with light microscope and transmission electronic microscope; the pulmonary wet-to-dry weight ratio, the pulmonary weight indexs, and the ratio of the area of the multilamellar body to the area of cytoplasm in type II alveolar cell were measured. Results 1.The permeability of the pulmonary endothelial cells increased 2 hours after the injection of oleic acid.

经光镜和透射电镜观察对照组和实验组三种组织的形态学改变；并测定肺组织的湿干重比和肺系数；采用立体计量法测定肺II型细胞板层小体与细胞质面密度比。

A-synuclein is a major component in Lewy bodies, a neuropathological hallmark of PD.

synuclein是Lewy小体的主要组成成分，在PD的发病机制中发挥重要的作用。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。