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Breast biomarker status changed in 9% of all lobular carcinomas and 19% of all ductal carcinomas.

所有的小叶癌和19%的导管癌的乳腺生物标记物的地位发生了变化。

Investigation of ductal carcinoma of no special type reveals covert tumour types, such as those with basal or myoepithelial features, whose distinctive features are only now being widely recognised.

对非特殊类型导管癌的研究揭示了隐藏的肿瘤类型,例如一些具有基底或肌上皮特征的肿瘤,它们的显著特征现在才被广泛认识。

The most common microbes causing infections in percutaneously inserted uncuffed catheters are, in order of prevalence, coagulase-negative staphylococci, Staphylococcus aureus, Candida species, and enteric gram-negative bacilli.

根据患病率的高低,引起经皮插入的无气囊导管感染的最常见的微生物排序如下:凝固酶阴性葡萄球菌、金黄色葡萄球菌、念珠菌属菌种和肠道革兰氏阴性细菌。

To pay attention to carry out effective cardiopulmonary resuscitation, hemostasis by compression and deep vein intubation rapidly in the initial stage of emergency. The carotid shunt tube plays an important role in severe carotid injury and re-establishment process. We use external jugular vein to transplant and re-establish,which are rung with artificial blood vessels for the long distance carotid injury and achieved the best result. We expose as fully as possible for the hepatic venae and the posthepatic post caval injury,and adopt effective methods to stop bleeding and repair. The application of blood shunt pump could raise the success rate for those severe patients. The self-double vastransplantation with both ends being all trousers-style one opening solve some problems such as there are no suitable caliber self-transplantation blood vessels and the artificial blood vessels are easy to occur obliteration for long-term and so on for the great or middle blood vessels.We use improved Fogarty duct and anterograde intubation to eliminate thrombus could eliminate thrombus effectively and avoid accessory injury for the deep vein injury and extensive thrombosis.

抢救初期要注意进行有效的心肺复苏、压迫止血和快速进行深静脉插管;颈动脉转流管在严重颈动脉损伤重建过程中有重要作用;对长距离颈动脉损伤用颈外静脉移植外环包人造血管重建,可取得最佳效果;对肝静脉及肝后下腔静脉损伤,要充分暴露,采用有效方法止血和修复,对病情极危重的凶险性出血者,血液转流泵的应用可提高成功率;对大、中血管损伤,两端均为裤式单开口自体双血管移植,解决了无适宜口径自体移植血管和应用人造血管远期易闭塞等问题;对深静脉损伤并广泛血栓形成者,应用改进的Fogarty导管和顺行插管取栓法,可有效取栓并避免了副损伤。

To pay attention to carry out effective cardiopulmonary resus-citation,hemostasis by compression and deep vein intubation rapidly in the initial stage of emergency.The carotid shunt tube plays an important role in severe carotid injury and re-establishment process.We use external jugular vein to transplant and re-establish,which are rungwith artificial blood vessels for the long distance carotid injury and achieved the best result.We expose as fully as possible for the hepatic venae and the posthepatic post caval injury,and adopt effective methods to stop bleeding and repair.The application of blood shunt pump could raise the success rate for those severe patients.The self-double vastransplantation with both ends being all trousers-style one opening solve some problems such as there are no suitable caliber self-transplantation blood vessels and the artificial blood vessels are easy to occur obliteration for long-term and so on for the great or middle blood vessels.We use improved Fogarty duct and anterograde intubation to eliminate thrombus could eliminate thrombus effectively and avoid accessory injury for the deep vein injury and extensive thrombosis.

抢救初期要注意进行有效的心肺复苏、压迫止血和快速进行深静脉插管;颈动脉转流管在严重颈动脉损伤重建过程中有重要作用;对长距离颈动脉损伤用颈外静脉移植外环包人造血管重建,可取得最佳效果;对肝静脉及肝后下腔静脉损伤,要充分暴露,采用有效方法止血和修复,对病情极危重的凶险性出血者,血液转流泵的应用可提高成功率;对大、中血管损伤,两端均为裤式单开口自体双血管移植,解决了无适宜口径自体移植血管和应用人造血管远期易闭塞等问题;对深静脉损伤并广泛血栓形成者,应用改进的Fogarty导管和顺行插管取栓法,可有效取栓并避免了副损伤。

Objective To compare the relationship between measurement of the time constantly derived from aortic regurgitant velocity spectra and catheter derived time constant, and to evaluate the effects of hemodynamic flow states and regurgitant volumes on the Tau AR.

目的 对比研究由主动脉返流频谱得到的时间常数Tau和心导管根据左室压力曲线得到的时间常数的相关性,评估血流动力学参数和返流容积对Tau-AR的影响。

To investigate the possibility of such a transition, we studied 17 cases of MGA or atypical MGA some of which had given rise to carcinoma in situ and/or invasive ductal carcinoma using the reticulin stain, immunohistochemistry (S-100, p63, Ki-67, and p53), and a molecular approach involving microdissection and high-resolution comparative genomic hybridization and MYC chromogenic in situ hybridization.

为了研究这种转变的可能性,我们分析了17例典型或非典型的MGA,其中一些已经发展成为原位癌和/或浸润性导管癌,所用的方法是网状染色、免疫组化(S-100, p63, Ki-67, and p53)和分子技术,分子技术包括显微切割和高分辨率比较基因组杂交及MYC显色的原位杂交。

A method of retrievably deploying an electrically driven downhole well fluid transducer system, such as an electrical submersible pump, comprises installing a production tubing (1), which is equipped near its lower end with one part of a wet mateable electrical connector (35) and an external electric conduit (15), and subsequently lowering the fluid transducer system, which is equipped with another part of a wet mateable electrical connector through the tubing until the wet mateable connector (19) parts engage each other.

本发明公开了一种可撤回地部署电动井下抽流器系统的方法,所说电动井下抽流器系统例如是一个电潜泵,该方法包括步骤:安装一生产油管(1),靠近其下端处装备了可湿接电气接插件(35)的一个部件和一条电缆导管(15);所说抽流系统上装备了可湿接电气接插件的另一个部件,随后将抽流系统经油管进行下放,直到使可湿接接插件(19)的两个部件相互接合到一起为止。

All the LOH on 〓 and 〓 was observed in invasive ductal carcino- ma, carcinoma simplex, medulary carcinoma and scirrhous carcino- ma, no deletions at these sites were observed in any invasive lobular carcinoma and others. These results imply an etiological difference.P53 gene is a hot point gene in the occurrence and development of breast, cancer. PCR-SSCP analysis was performed to detect P53 gene point mutation in the region between exon 5 and 8, 5 of 12 (41. 6%) stage I breast cancer patients contain mutation of P53, 3 of 5 patients were accompanied by 〓 deletion. These results suggested that point mutation and allelic loss of P53 gene are two vi- tal genetic events in earlier stage of breast tumorigenesis.

我们还发现,〓和〓位点LOH均分布在乳腺浸润性导管癌、单纯癌、髓样癌及硬癌中,在浸润性小叶癌和某些特殊类型乳腺癌中全部为LOH阴性,上述位点LOH可能与某些组织学类型乳腺癌的发生有关。P53基因是乳腺癌形成过程中的一个热点基因,本研究对12例Ⅰ期乳腺癌组织标本中P53基因热点区域第5、6、7、8外显子点突变进行了测定,发现41.6%(5/12)的病人有P53基因一个或多个点突变,其中3例同时伴有〓位点LOH,表明P53基因点突变和等位基因缺失是发生在乳腺癌形成早期的一个重要遗传学事件。

33 patients with AVD were studied by dynamic three-dimensional(3-D)reconstruction.18 men and 15 women 14-56 of age involved in this sutdy.Hewlett Packard 2500 echocardiography with 5.0/3.7 MHz multiplane transesophageal probe was used for data acquisition,and Tomtec echo scan system used for 3-D reconstruction.Acquired images were extracted and reconstructed by computer system.The condition of ATC and valve were viewed from atrioventricular lateral aspect.Results:The valvular replacement operations were performed on the patients suffered from thickened,calcified,thinned or broken tendinous cordae.

我们应用动态三维重建技术,研究了33例房室瓣病变患者的腱索,其中男性18例,女性15例,年龄14-56岁,全部病例经手术及/或心导管证实,图像采集使用HP SONOS 2500超声心动图仪(配有3.7/5.0MHz的多平面经食道探头),三维重建采用TOMTEC ECHO SCAN系统,将采集的图像提取并重建,从房室的侧面观察房室瓣腱索及瓣膜情况。

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