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Analysis of nuclear extracts of human cells has indicated a similar excision repair mechanism for nick-directed mismatch correction in higher cells, and several reconstituted systems that rely on purified human proteins have been described, such as hMutSα、hMutSβ、hMutLα. Recently, scientists discovered that nickel could be inhibitors of DNA repair. Nickel can greatly enhance the mutagenicity and genotoxicity of compounds in cigarette by inhibiting the nucleotide excision repair pathway in human cells. We have confirmed that nickel could inhibit MMR of E. coli and human and presumed that nickel inhibited repair before MutH incision of the MMR in E. coli. However, there is no evidence of mechanism of nickel inhibiting MMR in human cells.

镍是存在於香菸中的微量金属,近年来有学者发现镍是DNA修复反应的抑制剂,长期抽烟的人会容易因为香菸中化合物攻击DNA而引起突变,进而引起肺癌,而镍会抑制核苷酸移除修复系统(nucleotide excision repair;NER),所以使得体内的DNA损伤无法修复;过去实验室已经证实大肠杆菌的核酸配对错误修复系统会受到镍等重金属的抑制,并且推测出镍的抑制反应是抑制在修复反应的上游nicking的步骤;另外,也证实了人类的核酸配对错误修复系统也会受到镍的抑制,然而还没研究证实会抑制在核酸配对错误修复反应的哪个步骤。

College of Resources and Environment, Beijing Forest University,The Key Laboratory for Silviculture and Conservation of Ministry of Education, Beijing Forestry University, Beijing P.

北京林业大学资源与环境学院,北京林业大学省部共建森林培育与保护教育部重点实验室,国家林业局干旱半干旱地区森林培育及生态系统研究重点开放性实验室,北京,100083

It can provide verisimilar shift load for propulsive motor, and simulate the stable and dynamic property of the marine propeller that works under different conditions well and truly.Firstly this paper introduces the character of propeller and the effect between propeller and ship. Secondly provides a design of this simulating apparatus and selects some important parts according to the request of lab. Thirdly develops the simulating systems mathematical model to make engineering design and analysis.

本文首先分析了船用螺旋桨的工作特性以及与船体的相互作用;其次根据其特性制定了仿真装置的设计方案,并根据电力推进实验室的要求对仿真装置的主要部件进行了选择:然后建立了仿真系统的数学模型并对其进行工程设计及分析;最后详细介绍了仿真装置的DSP控制系统与主回路系统,并针对各部分的具体要求提供了相应的解决方案。

By using of the MIS system, the management, developing, appraising of a laboratory can be completed on Internet .

使实验室的管理、开放、评估都能在网上进行的高校实验室信息管理系统。

We simulate this system in laboratory successfully. The system work stably and operate easily. It can obtain the satisfied performance and high stability, follows the source well. The time of control improve obviously. It improve the system antijamming ability and comprehensibly improve the dynamic performance of system.

该系统在实验室仿真成功,系统工作稳定,操作方便,能够获得满意的性能指标,具有较好的快速跟随性,且稳态精度高,调节时间有了明显改善,提高了系统的抗干扰能力,全面的改善了系统的动态性能。

In recent years,microfluidic chip-based microanalytical systems have emerged as amain area of development in the field of micro total analysis systemsor Labchips,the ultimate objective of which is to integrate all main analytical functions,including sample introduction,pretreatment,reaction,separation and detection operations on asingle chip.

微流控芯片分析是微全分析系统(Miniaturized TotalAnalysis Systems,μTAS)或芯片实验室(Lab-on-a-chip)领域中的重要组成部分,其终极目标是在芯片上实现分析实验室的所有操作,包括取样、试样引渗入渗出、前处理、反应、分离和检测等。

Institute of Microbiology and Epidemicology, Academy of Military medical Science, Beijing,100071,China The performance of BL3 safety laboratory in preventing experimental aerosol diffusion and sterilizing microbe aerosols through high efficiency filter in a ventilation system was tasted.Aerosols of uranin, vibrio phage and Bacillus subtilis var. niger spores were used for the test.

P3级微生物安全实验室防气溶胶扩散性能的检测胡庆轩车凤翔摘要:采用荧光素钠、弧菌噬菌体和枯草芽胞杆菌气溶胶对P3级微生物安全实验室防气溶胶扩散性能及其排风系统中高效过滤器滤除气溶胶的效果进行了检测。

In order to improve the conventional method of laboratory management,a laboratory monitoring system based on GPRS is designed.

为了改进传统的实验室管理方法,设计一种基于GPRS的实验室监测系统。

Objective Combined barcode technique with laboratory information systems so as to improve automation degree in laboratory.

目的 把条形码技术与实验室信息系统相结合,提高临床实验室的自动化程度。

It was an argument that I once used when comparing our old lab to another computer lab of Apple Macintoshes.

曾经听到这样的议论,认为学生如果学习Linux,那么将来他所面对的会是另一个世界——即由微软操作系统和办公软件主导的世界,我将自己实验室与其他实验室的Macintoshe系统比较的时候也有这样的争论,当我重新评估开放软件时我发现这样的想法是片面的。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力