定向

ObjectiveTo study the generation and directional differentiation of BMSCs induced by Duzhong which can invigorate the kidney.

目的研究补肾中药杜仲含药血清对骨髓间充质干细胞增殖及定向分化的影响。

The combination of epidermal growth factor, basic fibroblast growth factor and insulin-like growth factor can effectively promote the directional differentiation of BMSCs into oligodendrocytes.

碱性成纤维细胞生长因子、表皮生长因子与胰岛素样生长因子联合应用能够有效促进骨髓间充质干细胞向少突胶质样细胞定向分化。

BACKGROUND: Muscle-derived stem cells have some problems in purification, amplification and directional differentiation during in vitro culture. Basic fibroblast growth factor as a membrane of bioactive factor has been paid great attention, due to its biological activity.

背景：肌源性干细胞在体外培养过程中存在纯化、扩增、定向分化等难题，碱性成纤维细胞生长因子作为生物活性因子的一员，因其生物活性的多效性而备受关注。

Objective To explore the possibility of basic fibroblast growth factor and epidermal growth factor combined with st-riatal conditioned medium promoting the directional differentiation of rat bone marrow mesenchymal stem cells into dopaminergic neurons.

目的 探讨联合应用碱性成纤维细胞生长因子、表皮生长因子和纹状体条件培养液定向诱导大鼠骨髓间充质干细胞分化为多巴胺能神经元的可能性。

OBJECTIVE: To establish an inducing system for differentiation of bone marrow mesenchymal stem cells into chondrecytes in two-dimensional culture in vivo, to analyze the best concentration of transforming growth favor beta-1 (TGF-β1) to induce the differentiation and the correlated influence factors for the directional differentiation, and to observe the changes of cell form and phenotype.

目的：建立二维培养条件下骨髓间充质干细胞分化为软骨细胞的诱导体系，分析转化生长因子β1作为诱导条件的最佳浓度，以及诱导骨髓间充质干细胞定向分化为软骨细胞的相关影响因素，观察细胞诱导后的细胞形态及表型变化。

Proteomics technology provides a powerful tool due to the large scale, systemical study of protein transformation and interaction, which can be used for exploring molecular mechanism of bone mesenchymal stem cells during directional differentiation.

蛋白质组学技术是大规模、系统性研究蛋白质变化及其相互作用的强有力工具，可以用于骨髓间充质干细胞定向分化的分子机制研究当中。

Objective Constructing the eukaryotic expression vector of mouse LIF and conducing to improve the directional differentiation research of ES cell about other laboratory animals.

目的 构建小鼠白血病抑制因子的真核表达载体，有助于开展高其他实验动物的胚胎干细胞的定向分化研究。

Currently ESCs have been used in the therapy of diabetes mellitus, Parkinson's disease and cardiovascular injury. Even though many problems of technique and ethics should be done, we believe that ESC therapy will be a promising method and used in clinical practice if we make clear the mechanism of ESC directional differentiation, establish an optimal culture system, and solve the problem of oncogenicity.

目前胚胎干细胞已经应用在治疗糖尿病、帕金森及心血管损伤等各种疾病中，虽然有很多技术问题和社会伦理问题需要解决与克服，相信随着胚胎干细胞定向分化机制的逐渐完善，优化培养体系的建立，致瘤性的解决，该细胞疗法作为一种新的治疗方式，将适用于临床使用。

OBJECTIVE: To establish an inducing system for differentiation of bone marrow mesenchymal stem cells into chondrecytes in two-dimensional culture in vivo, to analyze tbe best concentration of transforming growth favor beta-1 (TGF-β1) to induce tbe differentiation and the correlated influence factors for the directional differentiation, and to observe the changes of cell form and phenotype.

目的：建立二维培养条件下骨髓间充质干细胞分化为软骨细胞的诱导体系，分析转化生长因子β 1作为诱导条件的最佳浓度，以及诱导骨髓间充质干细胞定向分化为软骨细胞的相关影响因素，观察细胞诱导后的细胞形态及表型变化。

CD117; hemopoietic stem cells ; dendritic cells ; directional differentiation

CD117；造血干细胞；树突状细胞；定向分化

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。