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Hydroxysteroid dehydrogenase/carbonyl reductase ( 3α-HSD/CR,EC 1.1.1.50 ) from Comamonas testosteroni is an inducible enzyme which catalyzes the oxidation of androsterone with NAD+ to form androstanedione and NADH. 3α-HSD/CR was a member of the SDRs family, whose crystal structure had been solved by X-ray diffraction in 2000. The structure of 3α-HSD/CR is a homodimer which shows a typical pattern of Rossmann-fold structure consisting of βαβ units, and reaveals similarity with other members upon the SDRs family.

中文摘要 3α-Hydroxysteroid dehydrogenase/carbonyl reductase ( 3α-HSD/CR,EC 1.1.1.50 )是从Comamonas testosteroni菌体中分离而来的诱发性酵素,利用NAD+为辅因子,将受质androsterone氧化成androstanedione并伴随NADH的生成而完成催化反应。3α-HSD/CR是属於SDRs家族成员之一,其立体结构已经在2000年利用X-ray晶体绕射所解出。3α-HSD/CR在结构上为一同源双聚体,并和其它家族成员一样具有βαβ二级结构所叠合组成的Rossmann-fold特徵。

At the same time, the algorithms of hexahedral mesh generation using isoparametric transformation based on cylindrical coordinate and sphere coordinate respectively are also integrated with Subdivision-Mapping Method The technique of mesh gradient control is also presented.

还提出了扫描法六面体网格生成算法、基于圆柱坐标和球坐标系的使用等参映射法的六面体网格生成算法以及网格局部加密算法,并完成了相应模块的开发工作。

The formation of martensite is accomplished by the immigration of well-defined glissile interface (121)fcc type and its misfit dislocations can produce the lattice invariant deformation on the basis of phenomenal theory of martensitic crystallography, however, LID is retarded slightly after the migration of interphase (121)fcc, i.e.a thin plate-like zone exists without LID in martensite near the well-defined interface. When the temperature reduces to the Ms point, the lattice parameter of austenite matrix is √3/2 times that of the martensite without LID. This critical condition for spontaneous transformation agrees with that the stack fault energy in matrix is less than zero according to Olson and Cohen's nucleation model.

通过模型分析表明:fcc/bcc马氏体形核与长大过程是通过(121)fcc型择优界面推移进行的,界面上的错配位错可以完成马氏体晶体学唯象理论要求的点阵不变变形,但LID要稍滞后于界面迁移,即在马氏体形核与长大过程中推移界面新相一侧存在一未发生LID的新相薄区;当相变温度达到马氏体相变点Ms时,母相奥氏体与这一薄区的晶格常数比为√3/2,这一几何条件和Olson-Cohen形核模型中要求扩展位错层错区界面能γ≤0是等价的。

This paper consults the key technology in the radon measurement device in the national and international and we thinks over the characteristic of α-ray which emit by radon and its daughter, so that decides to use the α-ray spectrum to measure radon.

论文从测量氡及其子体放射出的α射线入手,瞄准国内外测氡装置关键技术发展趋势,结合氡及其子体α能谱测量特点,采用α能谱测氡的途径来完成这一工作。

Teeth of the total were revisited 2 years later and 2-year success rate were evaluated.Results The ratios of adequate filling, underfilling, and overfilling were 79.97%, 14.62% and 5.41%, receptively. Full canal RCT ratio of molar was 89.44%. Average RCT treatment period was 2.8 weeks. 2-year success rate of RCT was 94.39%.

下面就四川大学华西口腔医院牙体牙髓科 2 0 0 1~ 2 0 0 2年RCT的临床质量作一评价。1 材料和方法1.1 研究对象随机选择 2 0 0 1年 3月~ 2 0 0 2年 2月在四川大学华西口腔医院牙体牙髓科因牙髓病和根尖周病完成RCT治疗的 10 89例患者的 14 2 3颗患牙为研究对象。

The proposed method [5] is based on the sample correlation coefficient to normalize the signal Gerschgorin radii for source number detection. The second part of this reseach involving and construction of a TI TMS320C54XX [26-28] DSP developed platform. The platform will be used for developing H/W source number detectors.

同时,在第一年计划进行时,即著手於硬体电路的规划与设计,先行完成 DSP 发展平台,结合德州仪器DSP 大学实验室计画[24-25]所提供的简易初学板(TMS320C54X DSP Starter's kit)[23-24],加入自行撰写的开机载入程式,拉出多组重要资料/址线接脚讯号,制完成乙套多功能而价廉的DSP发展平台。

Aphids in the process of inhaling plant sap virus particles and auxiliary proteins also be inhaled, thus completing the process by poison, which also supports the field citrus aphid is non-persistent decline disease vector of disease, while the citrus Huanglongbing is phloem restricted by the bacteria caused the main pathogens present in the phloem, the fleas only by phloem feeding in diseased plants, pathogens in the body through the back to complete the salivary glands in the course of the next through the sieve tube feeding in the secretion of saliva the pathogens into the healthy tree, Citrus Huanglongbing different characteristics with aphid-borne diseases, Huanglongbing to persistent disease.

蚜虫在吸入植物汁液的过程中病毒粒子和辅蛋白同时也被吸入,从而完成获毒过程,这也支持了田间蚜虫是柑桔衰退病等非持久性病害传播介体,而柑桔黄龙病是由韧皮部限制性细菌类引起,病原体主要存在于韧皮部中,木虱只有通过在病株韧皮部取食,病原在体内完成循回到唾液腺中,在下一次取食过程中通过在筛管中分泌的唾液将病原体带到健树,柑桔黄龙病与蚜虫传病特点不同,黄龙病为持久性病害。

To acquire more information about gene expression at the whole-genome scale,our lab and National Engineering Center for Beijing Biochip Technology worked together and constructed the first genome-wide oligonucleotide microarray of the silkworm.This microarray was used to detect gene expression of 10 tissues/organs,including midgut,integument,head,hemocyte,testis,ovary,anterior/median silk gland,posterior silk gland,fat body and malpighian tubule.In this study,we performed analysis of these microarray data and confirmed the reliability of the results.

为了在全基因组水平上获得基因表达信息,本实验室与生物芯片北京国家工程中心合作,共同定制完成了世界上第一张家蚕全基因组寡核苷酸基因芯片,并利用该芯片对家蚕5龄第3天幼虫的中肠、体壁、头、血液、精巢、卵巢、前中部丝腺、后部丝腺、脂肪体、马氏管这10个组织中的基因表达谱进行了检测。

Under favorable condition, it multiplies as a unicellular organism. Upon starvation, a pathway involving aggregation, mound, slug, culmination stages induces the formation of a fruiting body consisting of a head of spores supported on a stalk of vacuolated cells.

在营养丰富条件下,以单细胞形式存在;一旦食物匮乏,单个细胞聚集成多细胞体,细胞历经细胞丘、蛞蝓体、拔顶阶段完成发育和分化过程,最终形成由孢子细胞和柄细胞组成的子实体。

Methods: The study included 10 patients (Male: 4, Female: 6; average age: 41.5) accessioned during May 2007 to August 2009 in Peking University School of Stomatology. The provisional restorations were delivery on implant after 3-6 months healing period of the implant.

2007年5月至2009年8月在北京大学口腔医院种植中心接受上颌前牙种植修复的患者10人(男4人,女6人,平均年龄41.5岁)共14个牙位,种植体骨结合完成后采用种植体支持的暂时冠对牙龈成型3~6个月。

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