学

OBJECTIVE To design and develop a clinical pharmacokinetics and individual drug dosage regimens system CPKDP program for estimating individual pharmacokinetic parameters and optimizing individualizing dosage regimens using routine clinical data of plasma levels. METHODS According to the principle of population pharmacokinetics and Bayes" formula, CPKDP program was written with FOXPRO 2.6 and BORLAND C++ 3.1, and was run on 486 microcomputer with UCDOS 5.0. RESULTS CPKDP program was adapted for drugs with different characteristics of pharmacokinetics, and for single dose or multiple dose administration. Using 1 or 2 measured drug concentrations, individual patient"s pharmacokinetic parameters were estimated based on population-average pharm-acokinetic parameters. CONCLUSION CPKDP program is applied for estimating pharmacokinetic parameters and optimizing drug therapy in individual patients.

目的为利用临床常规监测的血药浓度数据估算病人的个体药动学参数，优化给药方案，设计、研制了临床药动学给药个体化系统CPKDP程序方法依据群体药动学原理及Bayes公式，CPKDP程序用FOXPRO 2.6和BORLAND C++ 3.1开发，在希望汉字系统UCDOS 5.0平台上运行结果CPKDP程序适用于具有不同药动学特征的多种药物，适用于不同给药途径的单剂量或多剂量给药在群体药动学参数的基础上，结合病人个体特征，以1，2个血药浓度作为反馈，即可拟合估算个体药动学参数，优化给药方案结论经初步应用，CPKDP程序是应用Bayes反馈法开展临床个体化给药工作非常实用的工具

Zipperling Rong "Introduction to Exegesis," a book on the rise scholium, the development of scholium origins, Critical approach and the basic terminology scholium have made a comprehensive introduction to our more comprehensive display of Chinese Exegetics picture, but he shaped Yu in the shackles of traditional Chinese Exegetics not rule out the characters in the modern scholium the role, which is unscientific.

齐佩瑢《训诂学概论》一书对训诂学的兴起、训诂学的发展源流、训诂的方式及训诂学的基本术语等都作了全面介绍，较全面地向我们展示了训诂学的全貌，但他郁于字形对传统训诂学的束缚而完全否定了字形在现代训诂学中的作用，这是不科学的。

It is a refereed, broad-spectrum journal publishing basic research in diverse disciplines in biology and varied taxa. The journal publishes papers from major topics:animal, vegetation and plant population in ecology, mammalogy, animal behavior, herpetology, ornithology, aquatic ecology, parasitology, ichthyology, plant physiology and biological statistics.

它发表的文章内容囊括了生物学领域的各门学科的基础研究内容，比如：动物学，植被学，生态植物种群，哺乳动物学，动物行为学，爬虫学，鸟类学，水生生态学，寄生虫学，鱼类学，植物生理学和生物统计学等。

This thesis has made a deep study on lacustrine sequence stratigraphy and its application to oil and gas exploration and development, based upon the latest theory of sequence stratigraphy, limnology and petroleum geology incorporated with sedimentology, geophysics, tectonics, geochemistry, paleontology, paleoecology, ichnology, paleogeomagnatics and mislaneous analytical means.

"济阳坳陷下第三系沙河街组油气层序地层学研究"以层序地层学、湖泊学和石油地质学的最新理论为指导，充分利用丰富的地震、测井、岩心、录井和油藏工程等资料，综合沉积学、地球物理学、构造学、地球化学、古生物学、古生态学、遗迹学、古地磁学及多种分析测试手段对湖泊层序地层学及其在油气勘探开发中的应用进行了深入探讨。

The Council supervises the work of subject matter standing committees including: bacteriology; biochemistry, physiology, and molecular biology; biological control; chemical control; diagnosticians; diseases of ornamental plants and turf grasses, environmental quality and plant health; epidemiology; exobiology and space phytopathology; forest pathology; genetics; integrated pest management; mycology; mycorrhizae; nematology; plant disease detection; plant disease losses; postharvest pathology and mycotoxicology; seed pathology; soil microbiology and root diseases; tropical plant pathology and virology.

该协会主要研究范围涉及细菌学、生物化学、生理学、分子生物学、生物控制学；化学控制学；诊断学；观赏植物和草皮病理、环境质量与植物健康；流行病学；外空生物学和空间植物病理学；森林病理学；遗传学；病虫害综合管理；真菌学；线虫学；植物疾病诊断；植物病害损失；收割期后的植物病理学和真菌毒理学；种子病理学；土壤微生物学和植物根病理；热带植物病理学与滤过性微生物学等。

Main courses including: Human anatomy, histology and embryology, physiology, biological chemistry, medical immunology, medical microbiology, pathological physiology, introduction to general practice, Medical Ethics and health regulation, radiodiagnostics, nuclear medicine, integration of fundamental medicine, Pathology, pharmacology, diagnosis, introduction to surgery, internal medicine, surgery, obstetrics and gynecology, pediatry, integration of clinical medicine, clinical medicine statistics, clinical epidemiology, bio-medical informatics, psychiatry, neurology, lemology, traditional Chinese medical science.

主要课程：人体解剖学，组织胚胎学，生理学，生物化学，医学免疫学，医学微生物学，病理生理学，全科医学概论，医学伦理卫生法规，放射诊断学，核医学，基础医学综合课程，病理学，药理学，诊断学，外科学总论，内科学，外科学，妇产科学，儿科学，临床医学综合课程，临床医学统计学，临床流行病学，生物医学信息学，精神病学，神经病学，传染病学，中医学等。办公地点：理1-415，办公室电话：

It is well known that knowledge has tremendous amount like the sea , but what you can learn is only a little bit as a drop in the bucket, what you have mastered and what you are studying, as well as both what you will learn in the future and what you should be study all your life are all limited, but if you have learned a kind of method of thinking, so you will prolong what you have studied unlimitedly.

广博的知识是浩如烟海的，而你所能学到的也只不过是沧海中的一粟，你掌握的和现在学的包括将来要学的和你一辈子学的知识都太有限了，可是如果你学到了一种解决问题的方法，那么就可以将你所学的东西无限延伸。。。。。。。。。。。。。。。

There exits several MDO algorithms. But they are in our opinion either nonefficient or complicated. So we devised an algorithm called Subspace Approximation Optimization . In the SAO algorithm, the whole system is decomposed into one system-level optimization and several disciplinary optimizations so that a large and complicated problem can be divided into several easy-solving sub-problems. The coupling relationships and the coordination among disciplines are presented by equality constraints and these equality constraints are assigned to relevant disciplines. The optimums of design variables in system level optimization are transferred to discipline level optimization. The optimums of design variables in discipline level correspond to the point that is the nearest to the optimums of design variables in system level. If the optimums of design variables in system level are out of feasible region of discipline 1eve1, linear constraints can be built in the system level optimization using the design variable optimums obtained by the discipline level optimization. The system level optimization would improve the design of the whole system with these linear constraints.

目前，国内外已经发展出了多种飞机多学科设计优化算法，本文的重点是针对协同优化算法的不足，提出了子空间近似优化算法(Subspace ApproximatingOptimization，SAO)，SAO算法中，整个系统的优化问题被分解成一个系统级优化和若干学科级优化，而各个学科之间的耦合与权衡关系则被当作等式约束，这些等式约束将被分配到各个学科级优化中去，系统级优化的任务是寻找整个系统的最优解，而学科级优化的目标函数是以系统级优化分配下来的设计点为圆心的超球半径的平方，因此，如果系统级优化分配下来的设计点在学科级优化可行域内，则学科级优化目标函数为0，反之，则学科级优化的最优点是系统级优化当前设计点距离可行域最近的点。

The principal contents of the symposia on stratigraphy in the 31st International Geological Congress comprise the following aspects:geologic time scale, biostratigraphy, event stratigraphy, sequence stratigraphy, magnetostratigraphy, isotopic stratigraphy, integrated stratigraphy, sedimentary facies and palaeogeography, palaeobiogeography, and tectono-palaeogeography.

介绍了第 3 1届国际地质大会有关地层学学术讨论的主要内容，包括地质年代表、生物地层学、事件地层学、层序地层学、磁性地层学、同位素地层学、综合地层学、沉积相与沉积古地理、生物古地理、构造古地理 10个方面。

The handwriting and drawing motor of the students of different academic achievements differs in such ways as:a. Slow students\' motor control ability is inferior to that of the other students, which suggests some students have abnormal function of neural motor, including the unilateralization of brain function.b. The motor control ability of the excellent students from senior high school excels that of the other students.c. The harmonizing ability over double tasks of the excellent students exceeds that of the ordinary students. Such difference becomes more evident with complication of cognitive tasks.

三不同学业成绩学生的手书运动存在以下差异：1、学差生的手书运动控制能力低于学优生和中等生，提示在学差生中间可能有部分学生存在神经运动功能的特殊状况，包括大脑功能单侧化的改变。2、高中学优生的手书运动控制能力高于中等生和学差生。3、学优生在手书活动中的双任务协调能力优于学差生，随着认知次任务的复杂化，不同学业成绩学生之间的差异更为明显。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。