孢子丝菌病

These lesions have no characteristic features, and direct examination of material is useless.

诊断为孢子丝菌病的惟一途径是培养出申克孢子丝菌。

Sporotrichosis spread widely in the world.

孢子丝菌病在世界范围内广泛分布。

Traditional methods have limitations on the diagnosis of Sporotrichosis and on the identification of Sporothrix schenckii,which is difficult to meet the need of clinical diagnosis.

孢子丝菌病的致病菌是双相型申克孢子丝菌，传统的诊断方法对于孢子丝菌病的诊断及申克孢子丝菌的鉴定存在很大的局限性，难以满足临床诊断的需要。

This study suggests that 250 mg/day terbinafine is an effective and well-tolerated alternative to drug therapy of cutaneous sporotrichosis in a population in which itraconazole use is not possible.

这项研究表明，用特比萘芬以250mg/天的剂量治疗禁用伊曲康唑的皮肤孢子丝菌病患者是一种有效而耐受性好的药物替代疗法。

Slide 4-28 This is another example of the solitary lesion type of sporotrichosis.

幻灯4-28 这是另一例固定性孢子丝菌病的例子。这些损害并无特点，直接镜检无助于诊断。

Species-specific primers and probes which has been reported in the literatures of sporotrichosis were identified and laid a foundation for molecular diagnosis.

已见文献报道的孢子丝菌相对特异性引物和探针为孢子丝菌病的分子生物学诊断奠定了基础，但尚无资料对各种引物和探针进行过系统地比较。

Sporotrichosis is a fungal disease caused by Sporothrix schenckii that affects both dogs and humans.

孢子丝菌病是一种由申克孢子丝菌引起的人犬共患的真菌性疾病。

Diagnostic method of molecular Biology is of high sensitivity,specificity and fast detection,and it also has an advantage over the identification of Sporothrix schenckii in the level of species and strain,which is vital to the pristine diagnosis of Sporotrichosis and its therapeutic regimen and prognosis.

分子生物学诊断方法具有灵敏度高、特异性好、检测快速且可以在种、株水平对申克孢子丝菌病进行鉴定等优点，对于孢子丝菌病早期诊断及确定治疗方案和预后至关重要。

In this study,we attemped to use the same strain samples to compare the above three methods on the relationship between DNA patterns and geographic origins and clinical manifestations,to determine which is the best method on the genetic typing of S.schenckii. Also,we attempted to screen the highest specific and sensitive probe and primers from which had been reported of S.schenckii to lay the foudation for the rapid and correct diagnosis of sporotrichosis.

本研究旨在以相同的孢子丝菌菌株为样本，对以上3种方法进行比较，以确定在基因分型上哪种方法相关性更好、分辨力更强，并筛选出对孢子丝菌更敏感和更特异的探针和引物，为从基因水平上快速、准确诊断孢子丝菌病奠定基础。

Sporothrix schenckii (S.schenckii) is the causative agent of sporotrichosis, which affects primarily the skin,subcutaneous tissue,lymph vessels, lymphnodes and rarely,visceral organs.

申克氏孢子丝菌是孢子丝菌病的致病菌，主要引起皮肤、皮下组织和附近淋巴系统的亚急性和慢性感染，偶可播散至骨骼和内脏，甚至发生全身的播散性感染。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。