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孟德尔

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However, the mode of transmission is complex and non-Mendelian.

遗传因素对该疾病有很重要的影响,多年来为了寻找提高精神分裂症风险的DNA序列上的突变已付出了巨大的努力,然而该病的遗传方式非常复杂,并不符合简单的孟德尔遗传规律。

Yet, the complex, non-Mendelian disease etiology suggests that an epigenetic component could be involved.

然而,复杂的非孟德尔氏疾病的病因学表明,一个后生的组成部分与其有关。

It is a highly heritable and complex disease, in a polygenic, non-Mendelian fashion, possibly caused by the interaction of numerous minor effect genes and the influence of the environment.

精神分裂症是一种具有高度遗传性的复杂疾病,在亲代间的传递不遵循简单的孟德尔遗传模式,其致病原因可能涉及到多个微效基因间的相互作用以及环境因素的影响。

Decades of extensive efforts have been dedicated to the searching of DNA sequence variations that increase the risk. However, the non-Mendelian complex mode of transmission made genetic studies in Schizophrenia quite difficult.

大量的双生子、寄养子和家系研究的数据表明在精神分裂症的发病过程中遗传因素有很重要的作用,多年来为了寻找提高精神分裂症风险的DNA序列上的突变已付出了巨大的努力,然而该病的遗传方式非常复杂,并不符合简单的孟德尔遗传规律,使得遗传分析至今还没有获得令人满意的结果。

MtDNA is independent and non-Mendelian.

MtDNA,是独立的并且非孟德尔派的。

B chromosomes do not pair with A chromosomes,they are inherited in a non-Mendelian way, exhibiting meiotic and mitotic instability andnondisjunction. Bs have little influence with the phenotype. DNA sequence differences in rye genomes (JNK population with similar geneticbackground) with and without B chromosomes were analyzed by random amplifiedpolymorphic DNA.

目前,已在约1300种植物和逾500种动物中发现了B染色体,实际含有B染色体的物种数远远不止这些。B染色体具有许多独特的性质:它独立于A染色体之外,不与任何A染色体配对,为非孟德尔遗传,具有不分离机制,不携带或极少携带核仁组织区,无影响表型的基因。

Inspired by Psalm 42 in the Book of Psalms, Mendelssohn wrote the music during his honeymoon at age 29 and dedicated his tender and submissive love to God the Creator. His Symphony No.2, Lobgesang was influenced by Beethoven's Choral and he described it as a "symphony-cantata." The composer conducted as many as 500 people for its world premiere at Thomaskirche, Leipzig, creating a spectacular event.

这首来自诗篇42的泉涌灵思,在他29岁蜜月旅行时飘然入谱,他把温柔、深情、顺服的爱全然献给创造宇宙生命的上帝,新婚之心洋溢著哈利路亚;第二号交响曲《颂歌》,创意来自贝多芬的「合唱交响曲」,是首「交响清唱剧」的圣颂,当年在莱比锡汤玛士大教堂由孟德尔颂指挥五百人演、唱,盛况可想而知!

Lines transformed by particle bombardment have been discussed. The selectable marker bar gene cassette that integrated with the rice genome had multiple copies and showed complex segregation behavsensitive plants in their progenies. In five out of ten original transgenic lines, bar gene can be stably transmitted as a dominant gene to self-pollinated T2 progeny.

结果发现:作为筛选标记的bar基因表达盒在水稻基因组中多拷贝整合,遗传分离行为复杂,还出现了Basta抗感分离比在35∶1~144∶1之间的&假纯合体&,但50﹪转基因株系中(5/10)bar基因可作为一个显性基因按孟德尔方式稳定遗传至自交T2代。

Lines transformed by particle bombardment have been discussed. The selectable marker bar gene cassette that integrated with the rice genome had multiple copies and showed complex segregation behaviors including the presence of 'false homozygotes', with abnormal segregation ratios ranging from 35:1 to 144:1 (Basta-resistant: sensitive plants) in their progenies. In five out of ten original transgenic lines, bar gene can be stably transmitted as a dominant gene to self-pollinated T2 progeny.

结果发现:作为筛选标记的bar基因表达盒在水稻基因组中多拷贝整合,遗传分离行为复杂,还出现了Basta抗感分离比在35:1~144:1之间的&假纯合体&,但50%转基因株系中(5/10)bar 基因可作为一个显性基因按孟德尔方式稳定遗传至自交T2代。

Be able to explain Mendel's Law and the concept of gene, the complicate relationship between genotype and phenotype.

J-3 9 说明孟德尔定律及基因观念,解释基因型与外表型间的复杂关系,分辨常见的人类遗传疾病。

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