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In order to investigate the effect of IFN-γon the expression of TNF-αin the hypothala- mus-pituitary-ovary axisof RU486-induced aborted SD rats, RU486 was used to establish the abortion model, then the aborted rats were administrated with different doses of IFN-γintraperitoneal injection, the method of immunohistochemical ultrasensitive SP was us- ed to study the variation of positive TNF-αcells in hypothalamus, pituitary, ovary and uterus in normal pregnant group A, aborted model group B and three different doses of IFN-γgroup C,D,E. The main goal of this research was to study whether the low dose of IFN-γcould have a protective function to pregnancy and the mechanism of its function so as to provide morph- ologic basis for the scientific using of IFN-γin the process of animal abortion control.

为探讨IFN-γ对流产大鼠下丘脑-垂体-卵巢轴(hypothalamus-pituitary- ovary-axis,HPOA )TNF-α表达的影响,本试验用米非司酮(RU486)建立SD大鼠流产模型,通过腹腔注射不同剂量IFN-γ,采用超敏感免疫组织化学SP法(链霉素抗生物素—过氧化物酶法),观察了孕13天(d13)SD大鼠正常妊娠A组、流产模型B组、不同剂量IFN-γC、D、E组下丘脑、垂体、卵巢、子宫TNF-α的表达变化,探讨低剂量IFN-γ对妊娠是否有保护作用及其作用机制,期望能为在妊娠过程中如何科学应用IFN-γ防止动物流产提供形态学依据。

Objective To explore the value of laparoscopic operation in the treatment of gynecologic diseases.Methods Retrospective analysis of 170 cases of laparoscopic surgery in ynecology.53 cases in the salpingocyesis group,49 cases salpingotomy,4 cases salpingectomy;48 cases in the ovarian cyst group,35 cases enucleation and repair of ovary,8 cases ovary sutures atches,3 adnexnectomy and 2 perforation of ovary;52 cases in the uterine problems group,10 cases LM5 cases CISH,11 cases LSH(laparoscopic supracervical ysterectomy),14 cases LTH(laparoscopic total hysterecotomy),12 cases LAVH laparoscopically assisted vaginal hysterectomy);17 cases in the infertility group were studied in terms of lysis of pelvic adhesions and salpingostomy.

目的 探讨妇科腹腔镜手术的临床应用价值方法回顾性分析170例妇科腹腔镜手术病例,其中异位妊娠组53例,行输卵管切开取胚49例,输卵管切除术4例;卵巢疾患组48例,囊肿剥除术及卵巢成形术35例,卵巢缝合修补8例,患侧附件切除3例,囊卵巢多点打孔2例;子宫疾病组52例,行肌瘤剥除10例,改良CISH术5例,子宫次全切除术11例,子宫全切术14例,腹腔镜辅助阴式子宫切除12例;不孕症组17例,行盆腔粘连分解输卵管伞造口术。

Including salpingectomy,salpingotomy, salpingostomy, excision and enucleation of ovarian masses,repair of ovary, perforation of ovary, adnexnectomy, removal of hysteromyoma, supracervical hysterectomy, LAVH, CISH, lysis of pelvic adhesions, uterine suspension, uterosacral ligment transection, tubal sterilization, peritoneovaginoplasty.

手术包括输卵管切除术、输卵管切开吸胚术、输卵管造口术、卵巢肿块的剔除及切除术、卵巢修补术、卵巢多点打孔术、附件切除术、子宫肌瘤剔除术、子宫次全切除术、腹腔镜辅助的子宫切除术、腹腔镜筋膜内子宫切除术、盆腔粘连松解术、子宫悬吊术、骶韧带切断术、绝育术、取环术、腹膜阴道成形术等。

objective:to explore the value of laparoscopy in diagnosis and treatment of female infertility.methods:the clinical data of 139 cases of female patients with infertility were analyzed retrospectively.results:among 139 cases,55 cases with pelvic adhesion,34 cases with salpingitis,20 cases with endometriosis,and 14 cases with polycystic ovary.the pregnancy rates were 47.27%,41.18%,55.56% and 46.15% respectively after laparoscopic surgery.pelvic adhesion salpingitis and endometriosis were the major cause of female infertility.conclusions:laparoscopic technique can find out the reason of infertility more earlier and more directly and provide timely therapy.so it has excellent clinical effect.

目的:探讨腹腔镜诊治女性不孕症的应用价值。方法:回顾分析我院2004年12月至2007年12月应用腹腔镜诊治女性不孕症139例患者的临床资料。结果:139例中盆腔粘连55例,输卵管炎34例,子宫内膜异位症20例,多囊卵巢综合征14例,术后妊娠率分别为47.27%,41.18%,55.56%,46.15%。盆腔粘连、输卵管炎、子宫内膜异位症是引起女性不孕的主要盆腔病因。结论:应用腹腔镜技术能早期、直观、准确的明确不孕症输卵管及盆、腹腔病因并可同时予以针对性治疗,在直视下通液,动态观察输卵管通畅度和形态,大大降低了常规通液术的假阳性、假阴性率。

Methods Adenomyosis was diagnosed under lapososcopy in 4 infertile cases. Meanwhile coexsting endometriosis,pelvic adhesion and adenomyoma were treated by surgery and endocoagulator in 4 and 2 cases respectively.GnRH-α therapy was given for six months before laparoscopic surgery in 1 case and after laparoscopic surgery in 3 cases .

4例有严重痛经的子宫腺肌病伴不孕症患者经B超及腹腔镜或病理检查确诊,在腹腔镜检查的同时手术矫治合并存在的子宫内膜异位症和盆腔粘连。4例中,3例子宫后壁有局限性腺肌瘤形成(其中2例在腹腔镜下行手术切除)。3例于术后、1例于术前注射长效缓释型GnRH-α,每月1次,共6次。

Methods adenomyosis was diagnosed under lapososcopy in 4 infertile cases. meanwhile coexsting endometriosis,pelvic adhesion and adenomyoma were treated by surgery and endocoagulator in 4 and 2 cases respectively.gnrh-α therapy was given for six months before laparoscopic surgery in 1 case and after laparoscopic surgery in 3 cases .their fecundity outcome were followed-up after cessation of gnrh-α treatment.

4例有严重痛经的子宫腺肌病伴不孕症患者经b超及腹腔镜或病理检查确诊,在腹腔镜检查的同时手术矫治合并存在的子宫内膜异位症和盆腔粘连。4例中,3例子宫后壁有局限性腺肌瘤形成(其中2例在腹腔镜下行手术切除)。3例于术后、1例于术前注射长效缓释型gnrh-α,每月1次,共6次。

Abstract] Objective To compare the effect of different drug in the treatment of endometrial cyst of ovary after laparoscopy.Methods One hundred and fifty-four patients undergoing laparoscopy were divided into four groups,36 without endocrinal therapy;41 with danazol 400 mg qd;42 with gestrinone 2.5 mg qiw;35 with mifepristone 12.5 mg qd.

目的 比较卵巢子宫内膜异位囊肿腹腔镜手术辅以不同药物治疗的疗效方法 1998年8月~2003年2月我院卵巢子宫内膜异位囊肿腹腔镜手术患者154例,单纯腹腔镜手术组36例;加用丹那唑组41例,每日1次,每次400 mg,连服6 月;加用孕三烯酮组42例,每周2次,每次2.5 mg,连服6个月;加用米非司酮组35例,每日1次,每次12.5 mg,连服6个月。

Methods:The retrospective analysis and comparison were made on the operative method and the clinical index of intraoperation, postoperation between 103 cases underwent laparoscopic hysteromyomectomy and 100 cases underwent laparotomy hysteromyomectomy,also between 18 cases underwent laparoscope accessorial hysteromyomectomy and 20 cases underwent laparotomy hysteromyomectomy.

回顾对比分析腹腔镜子宫肌瘤剔除术103例与开腹子宫肌瘤剔除术100例,腹腔镜辅助下子宫肌瘤剔除术18例与开腹子宫肌瘤剔除术20例的手术方法和术中术后各临床指标。

objective to explore the best method of nursing in laparoscopic operation of subtotal hysterectomy with pk scapel.methods ninety seven patients under going operation of laparoscopic subtotal hysterectomy with pk scapel were slected.the bleeding volume,operation time and methods of nursing including machine check,proceeding and maintenance of instruments.results bleeding volume was lessened significantly and good nursing during operation can improve safety and success rate of losh.conclusion good nursing with well knowledge of pk scapel,accurate proceeding and sterilization and skilled cooperation plays a key role in assurance of the success of losh.

摘 要]目的:探讨在腹腔镜下使用pk刀行子宫次全切除术配合的方法。方法:对97例使用pk刀在腹腔镜下行子宫次全切除术配合进行总结,主要是检查测试仪器功能,按操作程序密切配合手术,术后正确彻底的清洗、保养、消毒与灭菌。结果:在腹腔镜下应用pk刀切除子宫,出血量明显减少,组织损伤小,97例的手术中除1例粘连严重中转开腹外,其余手术均顺利完成,无并发症发生。结论:护士加强对pk刀的应用学习,正确掌握操作规程和灭菌方法,以及娴熟的腹腔镜配合技术是手术顺利进行的有力保证。[关键词]腹腔镜;pk刀;子宫次全切除术;护理配合

Methods We retrospectively reviewed the clinical data of 321 cases of laparoscopic hysterectomy, including 201 classic intrafascial supracervical hysterectomy, 24 laparoscopic supracervical hysterectomy, 51 laparoscopic assisted vaginal hysterectomy, and 45 total laparoscopic hysterectomy. We compared the time of operation, the blood loss during operation and the restitution after operation in four groups, About the time of operation, the two methohs of amputating cervix were significantly longer than the two methods of remaining cervix.

对321例腹腔镜子宫切除术进行回顾性分析,其中腹腔镜鞘膜内子宫切除术201例,腹腔镜次全子宫切除术24例,腹腔镜辅助阴式子宫切除术51例,腹腔镜全子宫切除术45例,比较4种子宫切除术式的手术时间,出血量,术后恢复的情况。

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