失调

The use of animals has been central to the development of anaesthetics, vaccines and treatments for diabetes, cancer, developmental disorders..

使用动物对于发展麻醉学，疫苗以及糖尿病，癌症，发育失调等疾病的治疗具有至关重要的作用。

Tourism can help renovation and protection of ancient relics and historical sites, and accelerate urban construction and beautify environment.

旅游促进了文化古迹的修复和保护、城乡建设的发展和环境的美化，但同时又导致旅游资源的破坏、生态平衡的失调和传统文化的改观。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

An additional 10 percent of women report symptoms consistent with eating disorders such as anorexia,...

另外10 ％的妇女报告的症状与饮食失调，如食欲不振

Anorexia is one of the main eating disorders that affects a large number of people both in the USA and in Europe.

厌食症是一个主要的饮食失调，影响到许多人都在美国和欧洲。

The most common reported clinical symptoms are: hearing impairment (95%), cerebellar ataxia (88%), pyramidal signs (76%), dementia (24%), anosmia (17%), anisocoria (10%) and sensory signs (13%).

最常见的临床表现为：听力损害（95%）、小脑性共济失调（88%）、锥体束征（76%）、痴呆（24%）、嗅觉丧失（17%）、瞳孔大小不等（10%）、感觉症状（13%）。

Join the acids matter, the brix to acid ratio high and joins the puerarin or the tea polyphenol, the effect of antialcoholism, avoid be drunk and corrects the ataxia function more obvious.

解酒配方中加入酸类物质的、糖酸比值较大的和加入葛根素或茶多酚的，解酒、防醉和纠正运动失调的作用效果更为明显。

Tea polyphenol's effect of antialcoholism and avoid be drunk better than puerarin, but puerarin the effect of corrects the ataxia function is more obvious than tea polyphenol.

其中茶多酚的解酒、防醉效果比葛根素明显，而葛根素的纠正运动失调作用效果比茶多酚明显。

During this time I was diagnosed with anticipatory anxiety disorder.

就在那个时候，我被诊断出患有预想性焦虑失调症。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐