失

The study gives us the following conclusion through the analysis of teacher's strategies: Firstly, teachers' strategies are three characteristics including rule-control strategy is dominant in all ones, teachers are generally using strategy group to cope with ""anomie"" activities in a context of ""anomie"", teacher's strategy is flexile in different context.

本研究采用质的研究方法，通过现场观察、访谈收集资料，深入分析了&'失范'-策略&行为事件的过程，通过对幼儿&失范&行为产生的原因分析，得出两方面的结论：其一是幼儿内部原因，包括认知水平的限制、幼儿的情绪特点、幼儿的能力限制；其二是幼儿外部原因，包括规范本身、活动环境、教育活动的不适宜。

The syndrome of the most dementia patients from this study are inter-mediate level .The result of this study shows that the longer period patients got dementia and the more time caregivers have spent for caring patients, and the worse ADL, deviant behaviors and emotions of patients, the havier burden the caregivers would get.

样本群主要以中重度失智患者为主，本研究分析结论显示：当患者罹患失智症越久、照顾者照顾时间越长、照顾者每天花费於照顾患者的时间越多、患者之日常生活功能越差、患者之行为情绪问题越严重时，则照顾者之照顾负荷将越重。

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

The social capital and community construction connect with each other closely,the scarcity of the social capital is the important reason why inharmonic phenomena have appeared in setting up the harmonious community.

然而，中国目前的社区建设中存在着诸多失谐现象，导致社区严重的失序状态，影响整个社会秩序的稳定。

We propose a new mechanism of ASFC, which based on energy transfer among the centers within the inhomogeneously broadened spectral profile. We discuss it in two situations: small energy mismatch and large energy mismatch. The dependence of relative cooling efficiency on excitation photon energy and temperature is also discussed in evaluating the new mechanism.

提出了荧光光谱的非均匀线形内不同发光中心的能量传递产生荧光制冷效应的理论，分别对小能量失配的传递过程和大能量失配的传递过程进行了研究，认为在一定的条件下这两种过程都可以产生荧光制冷效应，并给出了相对制冷效率。

Aiming at slope types, features, deformation traits and destroy mechanism of high steep valley slope at Jinping Ⅰ Hydropower Station, and applying monitoring results, a comprehensive prediction design is suggested. In the space, according to the occurrences of unfavorable geological phenomena such as faults F5, f(subscript 42-9) deep fracture SL(subscript 44-1) and lamprophyre vein X, all of them can be treated as the boundary conditions for slides, potential instable blocks of slope on the left abutment are estimated which take on a wedge-shaped sliding model. In the sametime, through using three kinds of joint prediction methods such as statistic models and nonlinear models, judging from the shape of curves of deformation-time and their deformation velocities, it is found that the slope is at the state of slowly creeping to uniform deforming with a deforming velocity of 0.05 mm/d.

针对锦屏一级水电站左岸高边坡的边坡类型、边坡特征、变形特点和变形机制，在监测成果的基础上，对其进行综合预报，空间上判断左岸拱肩边坡由断层F5，f(下标 42-9)、深部裂缝SL(下标 44-1)及煌斑岩脉X互相组合，形成可能边坡失稳块体的边界条件、楔型体滑移失稳模式：时间上采用统计模型及非线性模型多种方法联合预报，根据边坡变形时序曲线的形态及变形速率指出：边坡目前处在缓慢蠕动至匀速变形阶段，变形速率小于0.05mm/d。

Dry that injured the windpipe and skins and the defenced of "lanket of Cilla-mucus"and reduced the expression of bcl-2 gene, which was related to the mechanisms of Cool??Dry.

凉燥伤肺、伤津，致气道&纤毛-黏液毯&局部御邪屏障受损；肺津凝滞于肺，以致宣输失司则皮肤失养。

ConclusionIt has first provided the evidences of CoolDry that injured the windpipe and skins and the defenced of "lanket of Cilla-mucus"and reduced the expression of bcl-2 gene, which was related to the mechanisms of CoolDry.

凉燥伤肺、伤津，致气道&纤毛-黏液毯&局部御邪屏障受损；肺津凝滞于肺，以致宣输失司则皮肤失养。本结果为凉燥致病提供实验资料。

ConclusionIt has first provided the evidences of Cool Dry that injured the windpipe and skins and the defenced of "lanket of Cilla-mucus"and reduced the expression of bcl-2 gene, which was related to the mechanisms of Cool Dry.

凉燥伤肺、伤津，致气道&纤毛-黏液毯&局部御邪屏障受损；肺津凝滞于肺，以致宣输失司则皮肤失养。本结果为凉燥致病提供实验资料。

Inactivation of anterior cingulate cortex and parafascicular or mediodorsal thalamic nuclei, which comprise the medial pain system representing pain affection, substantially impaired this observational fear learning, whereas inactivation of sensory thalamic nuclei had no effect.

前扣带回皮质、束旁或背中部丘脑核组成了代表痛苦感的内侧疼痛系统，一旦失活将会大大损害通过观察习得恐惧感的能力，而感觉丘脑核失活则没有影响。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。