天疱疮

Pemphigus vulgaris is a life-threatening autoimmune bullous dermatosis and its management represents a major challenge to medical teams.

天疱疮是一种有可能致命的皮肤水疱病，它的治疗对医疗团队是一个很大的挑战。

Pemphigus vulgaris is an autoimmune bullous disease that involves skin and mucous membrane.

寻常天疱疮是一种自身免疫性疾病，包括皮肤及粘膜的损害。

Objective: To investigate the expression of Th1 chemokine CXCL11/I-TAC and its receptor CXCR3 in the lesions of bullous pemphigoid.

目的： 研究Th1趋化因子CXCL11/I-TAC及其受体CXCR3在大疱性类天疱疮皮损中的表达。

Bullous pemphigoid is most commonly seen in Dobermanns and Collies and appears as a scald-like lesion of the groin.

大疱性类天疱疮最常见于杜宾犬和柯利犬，表现为腹股沟处的烫伤样病变。

In the 188 patients with extensive bullous pemphigoid,topical corticosteroids were superior to oral prednisone (p=0.02), with one-year survival rate 76% vs. 58%, disease control at three weeks 99% vs. 91%, and severe complication rate 29% vs.

188位广泛性大水疱性类天疱疮患者中，外用皮质肾上腺类脂醇的效果优於口服prednisone（p＝0.02），二者的年生存率分别为76％及58％，三周疾病控制率分别为99％及91％，而严重并发症发生率则分别为29％及54％。

Methods: To retrospectively analyze clinical data of pemphigus patients in 84cases, all medicines were glucocorticoid, and immunodepressant medicine were used by 45 cases of the total, and 3 patients of 45cases chose autologous peripheral hematopoietic stem cell transplantation. To observe hormone dosis、therapeutic efficacy、adverse reaction and prognosis information of all patients.

回顾分析84例天疱疮患者的临床资料，治疗药物均以糖皮质激素为主，45例患者同时加用免疫抑制剂（其中3例因治疗效果差进行了自体外周血干细胞移植），观察激素用量、治疗效果、副作用以及预后情况。

Numerous case reports featuring its off-label use suggest the drug could be helpful in treating hidradenitis suppurativa, pyoderma gangrenosum, Sweet's syndrome, cutaneous sarcoidosis, pemphigus, systemic vasculitides, multicentric reticulohistiocytosis and stomatitis.

许多以非常规用药为特色的病例报告指出，该药物有助于治疗化脓性汗腺炎、坏疽性脓皮病、Sweet综合征、表皮结节病、天疱疮、系统性血管炎、多中心网状组织细胞增多症和口腔炎。

Background Familial benign chronic pemphigus or Hailey-Hailey disease (HHD; OMIM 169600) is a rare autosomal dominant cutaneous disorder characterized by recurrent vesicles and erosions mainly in intertriginous areas.

研究背景：家族性慢性良性天疱疮，又称Hailey-Hailey病(HHD，OMIM 169600)是一种罕见的常染色体显性遗传性皮肤病。

Objective: In the sera of most bullous pemphigoid patients, there are auto-antibodies to the basement membrane zone, that fixed on lamella lucida of BMZ was found by immune-electronic microscope, suggesting the disease is a autoimmune disease.

目的：大疱性类天疱疮(bullous pemphigoid，BP)多数患者的血清中存在抗基底膜带成分的自身抗体，免疫电镜显示这种抗体结合在基底膜带的透明板，因此本病为一种自身免疫病。

The most common form in dogs is pemphigus foliaceus, which manifests as erosions and crusting of the skin and mucocutaneous junctions.

犬类中最常见的种类是落叶型天疱疮，表现为皮肤和粘膜交界处的皮屑和糜烂。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。