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The EAE rats were induced by injecting subcutaneously an emulsion of GPSCH and CFA. In addition, each rat received an intracutaneous injection of pertussis. Albumin in serum and CSF samples was examined on the days of 4,6,8,10,12,14,16,18 and 20 p.i.. The integrity of BBB was assessed by caculating CSF to serum albumin quotient. At the same time the brains, spinal cords, thymus and inguinal lymph nodes were removed for paraffin sections cutting. These sections were used for HE staining and ICAM-1 semiquantitative immunohistochemical staining. The results showed as follows:1. None of EAE rats on days 4,6 and 8 p.i. showed clinical signs whichbecame apparent on day 10 p.i.(2.33±0.76; n=6). On days 12 and 14 p.i.

检测p.i。第4天、6天、8天、10天、12天、14天、16天、18天、20天血清和CSF中ALB含量,其CSF/S ALB比值作为评价BBB损害的指标;同时段取动物脑、脊髓、胸腺和腹股沟淋巴结制成石蜡切片行HE染色和ICAM-1半定量免疫组化分析,结果显示如下: 1、EAE大鼠p.i.4-8天无任何临床表现;p.i.10天症状开始明显,症状评分为2.33±0.76(n=6);p.i.12-14天为发病高峰期,症状评分为3.75±0.54(n=12),病情由最初的活动减少,体重减轻逐渐发展为肢体无力、瘫痪,共济失调,甚至濒死状态;p.i.16天大部分动物症状开始缓解,评分为2.08±0.66(n=6);p.i.20天疾病症状完全消失。

I long to carry you all in my maternal arms and to present you to God Father in heaven.

我很想把你们拥抱在我的慈怀内,然后呈献给在天大父。

Mornings before daylight I slipped into cornfields and borrowed a watermelon, or a mushmelon, or a punkin, or some new corn, or things of that kind.

一清早,天大亮前,我便溜进玉米田,借一只西瓜或是甜瓜,或是南瓜,或者几个刚熟的玉米,诸如此类。

There were four newly hatched chicks, a day old - little specks of pulsating life no more than a mouthful; and he ate them ravenously, thrusting them alive into his mouth and crunching them like eggshells between his teeth.

窝里有四只刚出壳的小松鸡,才一天大——就像点点跳动着的生命之光,还不够他吃上一口;他把它们活活塞进嘴里,贪婪地大嚼大咽,像嚼蛋壳似地把它们在齿间碾碎。

The press continued rolling and by the end of the day over 1,116,000 copies were sold, a record that would not be beaten until the day of David Berkowitz's arrest.

新闻界继续轧到去年底的一天超过111.6万份出售,纪录将不会被殴打,直到有一天大卫Berkowitz的逮捕。

Student: The Kazak notorhynchus platycephalus you think the huge teacher's shortcoming?

学生:哈哈那你觉得天大老师的缺点?

The earth hums to me today in the sun, like a woman at her spinning

天大地在太阳光里向我营营哼鸣,象一个织着布的妇人,用一种已经被忘

The work went slowly and consumed most of the day.

他们的工作缓慢,一天大部分时间都耗掉了。

We also present single-step assembly of DNA oligonucleotides by PCR to synthesize a Bacillus spp. uricase gene in vitro.

最后,利用改良式的呈色法检验比传统检验更有效率,把分析所需时间从 4 天大大地减少至不到 20 小时。

The Giants had won the pennant, completing one of the unlikeliest comebacks baseball has ever seen.

巨人队最终赢得了锦旗,完成了棒球史上最不可能的一次惊天大逆转。

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And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47:5 法老对约瑟说,你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法,同时,采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。

Hey Big Raven, The individual lies dont matter anymore - its ALL a tissue of lies in support of...

嘿大乌鸦,个别谎言的事不要再-其所有的组织的谎言,在支持。