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Methods: Tumor cell-platelet adhesion of highly metastatic SACC-LM, non-metastatic SACC-83 and effect of aspirin, arginine-aspartate , magnesium acetylsalicylate on adhesion were studied in vitro. Antimetastatic effect of aspirin, RD, magnesium acetysalicylate on experimental metastasis of SACC was observed in vivo.

体外实验观察高转移潜能的SACC-LM细胞、非高转移潜能的SACC-83细胞与血小板的粘附,阿斯匹林、阿斯匹林镁、精氨酸-天冬氨酸(arginina-aspartate,RD)对SACC-LM细胞与血小板粘附的影响;动物实验观察阿斯匹林、阿斯匹林镁、RD对SACC-LM细胞实验性肺转移的作用。

According to the characters of bittern extraction, transportation, and follow-up Ammonia-soda industry of Jiangsu Oilfield, we studied the Synthetic methods and conditions ...

根据江苏油田的采出、输送卤水和后续氨碱工业生产的特点,研究了聚天冬氨酸PASP和有机膦酸LZ-06阻垢剂的合成方法和条件。

Results The mortality of senile group was 6.60%, it has signifacantly higher than that of control group and the value of ALT, AST, SB in senile group were significantly higher than those in control group before treatment, the cure rate of ALT,AST in senile group was significantly lower than that in controul group and the cure rate of SB has no significance in two groups.

治疗 老年组的丙氨酸氨基转移酶、天冬氨酸氨基转移酶、总胆红素值显著高于对照组,老年组ALT、AST的治愈率显著低于对照组,而SB的治愈率在两组中差异无显著性。

OBJECTIVE: To probe into the progression of biochemical study on caspase-3 and its functions in disorders of center nerve system.

目的:探讨半胱氨酸天冬氨酸蛋白酶3的分子生物学研究进展及它在中枢神经系统疾病中的作用。

Tranquilize the mind and improve sleep, and nourish the nerve: Royal Jelly contains three amino acids that are the neurotransmitter for brain, like glycine that can inhibit the cerebral nerve activity, like glutamic acid and aspartic acid that can excite the nerve cells.

镇静安眠、滋养神经,王浆中有3种氨基酸是大脑的递质,甘氨酸能抑制脑神经细胞的活动,天冬氨酸和谷氨酸都能兴奋神经细胞,对预防自主神经功能而引起的头晕、恶心、食欲不振等综合症有奇效。

MethodsAfter acate liver injury model was induced by carbon tetrachloride (CCl4), mice were administrated intragastrically with Hypericum japonicum.The serum ALT, AST, SOD, NO, TNF-α, IL-6 were determined and pathological change of liver was observed.

方法以四氯化碳(CCl4)制备小鼠急性肝损伤的模型,田基黄水煎剂灌胃,检测小鼠血清中的丙氨酸氨基转移酶、天冬氨酸氨基转移酶、超氧化物歧化酶活力以及一氧化氮、肿瘤坏死因子-α、白介素-6的含量,观察肝组织的病理损伤程度。

According to the results of quantum chemistry calculation and the present research status in the relationship between the structures and the functions of DT, the El 54 in DT catalyzing domain was mutated to aspartic acid and arginine in order to study the effects of the alteration on the biological activities.

在量子化学计算的基础上,结合目前关于白喉毒素结构与功能的研究状况,选择把白喉毒素催化区的第154位谷氨酸分别突变为天冬氨酸和精氨酸,研究此处电荷性质的改变对生物活性的影响。

It revealed high inhibition specificity toward serine proteinases (bovine trypsin, bovine chymotrypsin, and porcine trypsin). It did not exert any inhibitory activity toward cystein proteases and aspartyl proteinases.

丝氨酸蛋白酶抑制剂对丝氨酸蛋白酶家族中的牛胰凝乳蛋白酶、牛胰蛋白酶、猪胰蛋白酶三种蛋白酶的活性均有强烈的抑制作用;而对半胱氨酸蛋白酶家族中的木瓜蛋白酶及天冬氨酸蛋白酶家族中的牛胃蛋白酶几乎没有作用。

In sham-operation group,animals were decollated and their brains were taken out at 24 hours postoperatively. In all the groups, hippocampal brain injury was detected using histopathological method combined with semi-quantified RT-PCR methods for detecting caspase-3 mRNA. Adult rats aged 90 days were used in modified y maze to examine their learning and memory functions. All these three experiments were independent.

各组海马区脑损伤行组织病理学检测,半胱氨酸天冬氨酸蛋白酶-3 mRNA的表达采用半定量反转录-聚合酶反应方法进行检查,成年90 d龄的大鼠进行三等分迷宫测试其学习记忆能力,3个实验各自独立。

Methods: Liver injure rat models were made by alcohol, the high-dose and low-dose ZhiGanQing Capsule were continuously watered by for 8 weeks, the contents of AST、ALT and TG were detected separatedly, and the hepatic pathology was observed too.

采用白酒复制大鼠肝损伤模型,脂肝清胶囊按高、低剂量灌胃,连续8周,测定血清天冬氨酸转氨酶、丙氨酸转氨酶及甘油三酯的含量,并观察肝脏的病理组织学改变。

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