大鼠

Methods Forty rats were randomized into normal control group and FS group. The normal control group was fed with conventional forage. FS group was fed with dry forage mixed with FS powder for 3 months, the preliminary dose of FS was 200 mgkg^(-1)d^(-1) and then increased progressively by l00 mgkg^(-1)d^(-1) to ensure over half of the rats having diarrhea, and the final dose was 2800 mgkg^(-1)d^(-1). The frequency and amplitude of colic slow wave were detected and the changes of myenteric plexus and ICC were observed by zinc iodide -osmic acid staining method.

方法］SD大鼠40只，随机分为2组：正常对照组、番泻叶组（饲以含番泻叶粉的乾饲料，起始剂量为200 mgkg^(-1)d^(-1)，以100 mgkg^(-1)d^(-1)剂量递增，保持对半数以上动物有泻下作用，连续3个月，终剂量为2800 mgkg^(-1)d^(-1)，检测大鼠结肠慢波的频率及振幅，采用碘化锌－锇酸法观察肌间神经丛及ICC变化。

Estrogen can effectively prevent bone loss by inhibiting osteal formation and resorption and decreasing bone transformation in ovariectomized rats, which may be related to the increased transcription of renal VDR.

雌激素能有效地抑制去卵巢大鼠的骨吸收和骨形成，降低骨转换，可能与促进去卵巢大鼠肾脏VDR mRNA的表达有关。

Results: OVX group, with weakened bone structure, had decreased cancellous bone and increased parameters of osteal formation and resorption compared with Sham, OVX+E and OVX+E+P groups(P.05). The bone mass, osteal formation and resorption in group OVX+P had no significant changes.

结果：与假手术组、雌激素及雌孕激素组相比，去卵巢大鼠松质骨骨量明显减少，伴有骨结构变差，骨形成和骨吸收的参数值增加(P.05)；与去卵巢组相比，孕激素组大鼠无显著改变。

METHODS: Osteoblastic cells from rats were incubated in the medium supplemented wiht rhgh at different doses (10, 200 μg/L), and then the changes of cytoskeleton and cell cycle were detected.

用浓度为10和200 μg/L的重组人生长激素加入大鼠OB培养体系，观察对大鼠OB的细胞周期及细胞骨架的影响。

The method of PCR-analyzed microsatellites can be used for distinguishing between inbred and outbred、different strains、strain and substrain.and it provides a lot of information for genetic mapping,gene location and heredity probe of the inbred rat strains,and a speedy、convenient method for genetic research of the inbred rat.

因此，本实验为开展近交系大鼠遗传作图、基因定位和为实验动物的遗传背景监测提供可靠的信息，为大鼠遗传基因的研究提供了一个快捷简便、特异准确的方法。

Both kinds of rats were inbred to construct the new inbred strains from Sprague-Dawley outbred strain background. In the first section, conventional visual electrophysiology was observed in CSNB and RCD rat.

在课题的第一部分，我们对这两种动物的视觉电生理性状进行了观察，包括：常规视觉电生理，CSNB大鼠的暗适应多焦点视网膜电图和明适应多焦点视网膜电图，RCD大鼠的不同颜色刺激光暗适应多焦点视网膜电图。

Treated with baicalin by oral administration, the content of glutamic pyruvic transaminase and glutamic oxalacetic transaminase could be degraded in the Alcoholic fatty liver of rats, and it had evident protection for the rats and mice'Alcoholic fatty liver.

黄芩苷灌胃给药后，可降低肝损伤小鼠及大鼠谷丙转氨酶和谷草转氨酶含量，对小鼠及大鼠肝损伤均有明显的保护作用。

Treated with prophylactic by oral administration, it also obviously degraded the content of Cholesterol, Triglycerides, glutamic pyruvic transaminase, glutamic oxalacetic transaminase, Maleic Dialdehyde and Tunmor Necrosis Factor in Alcoholic fatty liver of rats, and increased the contents of Albumin and Superoxide Dismutase.

并且可以明显减轻白酒对小鼠中枢神经抑制作用；经治疗灌胃给药，可以显著降低酒精性脂肪肝大鼠和小鼠，总胆固醇、甘油三酯、谷丙转氨酶、谷草转氨酶、丙二醛含量，降低酒精性脂肪肝大鼠肿瘤坏死因子含量，增加白蛋白和超氧化物歧化酶含量。

Pharmacodynamics experiments indicated that the drug obviously degraded the content of Cholesterol,Triglycerides,glutamic pyruvic transaminase and Maleic Dialdehyde in the Alcoholic fatty liver of rats and mice treated with by oral administration, it also degraded the content of glutamic oxalacetic transaminase, r-GLU,alkaline phosphatase and increased the content of Albumin and Superoxide Dismutase in the Alcoholic fatty liver of rats, and remarkably reduced depressant effect of the mice'centra nerve.

药效学实验表明，经预防灌胃给药，可以显著降低酒精性脂肪肝大鼠和小鼠，总胆固醇、甘油三酯、谷丙转氨酶、丙二醛含量，降低酒精性脂肪肝大鼠谷草转氨酶、γ-谷氨酰基转移酶、碱性磷酸酶含量，增加白蛋白和超氧化物歧化酶含量。

Four weeks later, the 24 h oxaluria concentration was measured, the apoptosis index of renal tubular epithelial cells was detected with TUNEL method, and Ca2+ fluorescence intensity of cells of renal proximal tubules was determined by flow cytometry using Fluo-3/AM staining.

测定各组大鼠24 h尿草酸浓度；TUNEL技术检测肾小管上皮细胞凋亡指数；应用Flou-3/AM荧光指示剂测定大鼠肾近曲小管细胞内Ca2+的荧光强度。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。