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Furthermore, in the CTA rats, compared with water stimulability, FLI neurons of SON and DMV induced by sucrose stimulability had had much more expressions.6 When the same sucrose stimulability was given, FLI neurons expressions of SON, DMV and LH in the CTA rats were much lowwer than that in the control rats.Conclusions:1 CTA had an inhibitory effect on small intestine peristalsis, indicate taste preference has an effect on small intestine peristalsis, and inhibitory effect induced by CTA is corresponded with US, this effect may have relations with vagus efferent never and humoral regulation.2 In the electrophysiology experiment, discharges of vagus efferent never in the CTA rats are much more than that in the control rats, indicates taste and taste preference may regulate small intestine peristalsis via vagus nerve, and dicharge can continude 1 hour, indicate humoral regulation also exists in the regulation.

结论1建立味觉厌恶对小肠运动有抑制作用,提示味觉嗜好性对小肠运动有影响,而且味觉厌恶引起抑制作用是与条件刺激成对应关系的,味觉刺激引起的小肠蠕动的抑制作用可能与迷走神经传出神经及体液调节有关。2在电生理实验中,CTA大鼠迷走神经传出放电高于对照组的大鼠,提示味觉及味觉嗜好性可能是通过迷走神经对小肠运动进行调节的,放电至能持续60min,表明味觉及味觉对小肠运动的调节中还有体液调节的参与。

Results rcbf in prefrontal cortex, parietal cortex, hippocampus and subcortex obviously decreased, especially on 24 h post operation, and was lower than that of normal group on 4 mon post operation obviously.

结果 大鼠双侧颈总动脉永久结扎后额叶、顶叶、海马及皮质下区的rcbf明显下降,以术后24小时最明显,至4个月时仍明显低于正常,呈慢性持续性下降的趋势;各实验组大鼠从术后1个月开始即出现明显的记忆功能障碍,至4个月时记忆功能障碍持续存在。

Results rCBF in prefrontal cortex, parietal cortex, hippocampus and subcortex obviously decreased, especially on 24 h post operation, and was lower than that of normal group on 4 mon post operation obviously. rCBF showed a tendency to decline. The cognitive functions of rats were obviously reduced after 1 mon of the chronic cerebral hypoperfusion and lasted until 4 mon.

结果 大鼠双侧颈总动脉永久结扎后额叶、顶叶、海马及皮质下区的rCBF明显下降,以术后24小时最明显,至4个月时仍明显低于正常,呈慢性持续性下降的趋势;各实验组大鼠从术后1个月开始即出现明显的记忆功能障碍,至4个月时记忆功能障碍持续存在。

Methods Chronic forebrain ischemia model was made by permanent occlusion of bilateral carotid arteries. The cognitive function of the rats were estimated by Morris water maze test and rCBF in prefrontal cortex, parietal cortex, hippocampus and subcortex was assessed by laser doppler flowmetry on any different timepoint after operation (24 h, 7, 14 d, 1, 2, 3, 4 mon).

采用双侧颈总动脉永久结扎方法制备慢性前脑缺血动物模型;应用激光多普勒血流仪检测各组大鼠术后不同时间点(术后24 h、1 w、0.5、1、2、3、4个月)额叶、顶叶、海马及皮质下区局部脑血流量;利用Morris水迷宫方法检测各组大鼠记忆功能。

Results Arc-needle injection 131I-iodinated oil in SMMC-7721 hepatoma at subcutis could increase rat's survival time, the body weight kept less descent, the lumps necrosed wholely.

结果 直形针给药组大鼠在注射后2周多数表现为体重下降,肿瘤增大,最后都死于全身耗竭;而弧形针组大鼠体重相对稳定,肿瘤组织表现为均匀坏死,缓慢崩溃,动物存活期明显比前者长。

To investigate the effects of basic fibroblast growth factor on necrosis rate, succinate dehydrogenase level and oxygen consumption of the skin flap, 18 Wistar rats were divided into 2 groups.

为了观察碱性成纤维细胞生长因子对大鼠缺血皮瓣坏死率、琥珀酸脱氢酶含量和氧耗量的影响,选用Wistar大鼠18只,随机分为对照组和实验组。

The PCP model rats were randomly divided into sulfanilamide treatment group and positive control group,the normal rats were randomly divided into normal control group and negative control group.

2实验分组:正常对照组,阴性对照组,阳性对照组(建立Pc模型未给磺胺药的大鼠)和实验组(建立Pc模型并用磺胺药治疗的大鼠)。

Methods: Sprague Dawley rats have been used as recipients and Wistar rats as donors. Donor aorta was anastomosed to the recipient's suprarenal abdominal aorta; donor pulmonary artery was anastomosed to the left renal vein of the recipient using continuous suture technique.

以Wistar大鼠为供体,SD大鼠为受体,将供心的主动脉和肺动脉分别与受体肾血管上方的主动脉和左肾静脉用连续缝合技术行端侧吻合。

Methods 42 Wistar male rats of hepatic fibrosis were induced by TAA and divided into 7 groups randomly (n=6). The rats of 1 model group were sacrificed every 2 weeks.

60只雄性 Wistar大鼠应用硫代乙酰胺饮用水喂养,制备肝纤维化模型。42只大鼠模型制备成功后,随机分为 7 组,每组6只。

METHODS: TAFI was activated by thrombin and throbomodulin, and the conversion of TAFI to TAFIa was detected by chromogenic assay. A rat lung fibrin deposition model was induced by batroxobin. The effect of elevated levels of TAFIa on endogenous fibrinolysis was studied in the rat model.

①用凝血酶及血栓调节蛋白活化TAFI,然后用TAFI活性测定试剂盒检测活化后的TAFI;②以[125I]-纤维蛋白原进行示踪,用batroxobin建立大鼠肺纤维蛋白沉积模型,并运用该模型研究TAFIa对大鼠内源性纤溶的作用。

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