大鼠

EPO was considered to be excreted only by the kidney and responsible for the proliferation, maturation, and differentiation of the precursors of the erythroid cell line incretory hormone.

在大鼠脑损伤模型中，EPO对抗损伤后炎症反应，并起到神经保护作用；在实验性自身免疫性脑脊髓炎大鼠模型和大鼠大脑中动脉梗塞模型的研究中发现，EPO可明显抑制促炎性细胞因子和趋化因子的产生，进而减轻炎症反应。

The experimental rats were randomly divided into normal group, ISO group, positive control group and leonurus composition groups.

采用大剂量异丙肾上腺素皮下注射，造成大鼠急性心肌缺血损伤模型，用药后检测各组大鼠Ⅱ导联心电图J点变化情况、心肌组织形态学变化、血流动力学变化及酶谱变化。

Methods The nitroglycerin experimental migrainous animal model was reconstructed for the expression of c-fos and c-jun by means of immunohistochemical method Results The nitroglycerin experimental migrainous rats appeared reddish two ears, head shaking,scratching head with forepaws, activity increasing, both the number increasing and the area enlarging of the positive cells of the expression of c-...

免疫组化ABC法研究偏头痛大鼠脑组织即刻早期基因c -fos、c -jun的表达。结果硝酸甘油型实验性偏头痛大鼠出现双耳发红、甩头、前肢频繁搔头，活动增加等外在表现，脑组织c -fos、c -jun基因表达阳性细胞数增加，基因表达阳性细胞的面积扩大、灰度降低或变化不大。结论硝酸甘油型实验偏头痛大鼠模型复制方法简单、重复性较好、脑组织c -fos和c -jun基因异常表达明显，可以作为偏头痛治疗药物筛选、药效评价和发病机理研究的动物模型。

objectiveto investigate the effect of myricetin dispersible tablets on experimental cerebral ischemia-reperfusion injury in rats and thrombosis formation.methodsexperimental cerebral ischemia-reperfusion injury model was induced by ligation bilateral common carotid arteries. the protective effect of myricetin dispersible tablets was observed by detecting the content of cerebral water, sod and mao activities,mda and la contents.

方法采用双侧颈总动脉结扎法制备大鼠实验性全脑缺血再灌注损伤模型，通过测定大鼠脑含水量，超氧化物歧化酶、单胺氧化酶的活性和丙二醛、乳酸的含量，观察杨梅素分散片对大鼠实验性脑缺血的影响；采用体内静脉血栓形成法，观察杨梅素分散片对体内静脉血栓形成的影响；并研究其对血小板聚集的影响。

MethodsExperimental cerebral ischemia-reperfusion injury model was induced by ligation bilateral common carotid arteries. The protective effect of myricetin dispersible tablets was observed by detecting the content of cerebral water, SOD and MAO activities,MDA and LA contents.

方法采用双侧颈总动脉结扎法制备大鼠实验性全脑缺血再灌注损伤模型，通过测定大鼠脑含水量，超氧化物歧化酶、单胺氧化酶的活性和丙二醛、乳酸的含量，观察杨梅素分散片对大鼠实验性脑缺血的影响；采用体内静脉血栓形成法，观察杨梅素分散片对体内静脉血栓形成的影响；并研究其对血小板聚集的影响。

Methods The rat models of neuroglioma were established,and divided into two groups. The rats in experimental group were lavaged with MMC 1 week after injected with C6 glioma cells, 10 mg.kg-1every day,the rats in control group were treated with sodium chloride at the same dose.

制备大鼠脑胶质瘤动物模型，将造模成功的大鼠随机分为对照组和实验组，实验组大鼠注射C6脑胶质瘤细胞1周后，每天灌胃给予10 mg.kg-1MMC，连续5 d；对照组给予相同体积的生理盐水。

METHODS:(1)The bile-pancreatic ducts of rats were ligated,the catheters were inserted into right jugular vein and jejunum and the acute pancreatitis model was established.Forty pancreatitic rats were divided into four groups and were given simple parenteral nutrition(PN,n=10),early enteral nutrition(EEN,n=10), median enteral nutrition(MEN,n=10),and late enteral nutrition(LEN,n=10) respectively.

(1)结扎大鼠胆胰管，经右颈静脉及空肠插管建立大鼠急性胰腺炎营养支持模型。40只急性胰腺炎大鼠分别给予：单纯肠外营养(PN组，n=10)，早期肠内营养(EEN组，n=10)，中期肠内营养(MEN组，n=10)，晚期肠内营养(LEN组，n=10)。

ZGF can effectively inhibite the expression of PCNA and AFP in rat hepatic precancerous lesion tissue, and ZGF has the function of lessening the paraplasm of rat hepatic precancerous lesion tissue.

大剂量正肝方能有效降低大鼠癌前病变肝组织PCNA和AFP的表达，减轻大鼠癌前病变肝组织的异常增生。

Methods 20 rats were randomly divided into A, B, C, D and E group. The models of cerebral anoxia in group A and C were made by hypopiesia and hypoxia, and the models of hypoxia-reoxgenation were made in group B and D. 24h and 1h before establishment of models, ginsenoside Rb3 was injected peritoneally in rats of group C and D, respectively. The number and form of GABA-like immunoreactive neurons in hippocampus CA1 area of rats after brain hypoxia-reoxgenation were investigated with immunohistochemistry.

將大鼠隨机分为A、B、C、D、E5组，A、C组以低压低氧暴露製作大鼠脑缺氧模型，B、D组为缺氧－复氧模型。C、D组动物分别於制模前24h、1h 2次腹腔注射人参皂甙Rh3溶液；採用免疫组化法，观察各组大鼠在缺氧及缺氧－复氧处理后海马CA1区GABA免疫反应阳性细胞形態及数量的变化，並与正常对照组比较。

Methods:(1) Silica column chromatography and LH-20 were used in phytochemistry study.(2) Based on the extraction ratio of arctiin, the best extraction procedure was acheived under the direction of L9(34) orthogonal experimental design. From 10 types of resins, the one with the maximal binding ability for Arctii was selected and silica-column choramatograpy was used in its seperation and purification procedure.(3) The animal diabetic experimental model in Wistar rats was established with streptozotocin and many biochemical factors were used to indicate the pharmacological effects of arctiin, including glycosylated hemoglobin, serum creatinine, seralbumin, monoxide nitrogen, glycerin trilaurate, cholesterol, HDL-ch, LDL-ch, Blood urea nitrogen, creatinine, SOD, ET, MDA, total Urine protein and albuminuria.

(1)采用硅胶柱层析、聚酰胺层析、LH-20等方法对牛蒡子的化学成分进行研究；(2)采用正交实验设计方法，以牛蒡子苷为指标，确定了牛蒡子乙醇回流提取的最佳工艺；对10种类型大孔吸附树脂进行筛选，筛选出对牛蒡子苷吸附效果最佳的树脂；采用硅胶柱层析法，对牛蒡子苷进一步分离纯化；(3)建立实验性糖尿病大鼠模型，以GLU、TC、TG、HDL-ch、LDL-ch、TB、ALB、BUN、CREA、GHbAlc、NO、SOD、ET、MDA和尿液中TB、ALB为指标，研究牛蒡子苷药理活性；(4)以差速消化法纯化Wistar大鼠的主动脉内皮细胞并进行传代培养，测定牛蒡子苷对高糖条件下RAECs活性、RAECs释放LDH、MDA和NO的变化以及RAECs表达内皮型一氧化氮合酶表达的影响。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。