大鼠

objective to study gastrodia elata blume to effect tau protein,sod,mda expression in gyrus hippocampi and cerebral cortex of experimental mice.methods to inject okadaic acid to mice ventriculus lateralis and to measure tau protein level,sod activity and lipid superoxide mda content of sod control group,oa injection group,oa and gastiodia elata injection solution group.results tau protein of experimental group(p＜0.05/p＞0.05),sod was lower than model group(p＜0.001) and was higher than control group(p＜0.05).conclusion gastrodia elata blume can increase sod activity and reduce tau protein expression and superoxide lipid forming in brain tissue of experimental dementia mice caused by oa.it can prevent and treat ad.

目的 观察天麻对痴呆模型大鼠海马、皮质神经元微管相关蛋白、超氧化物歧化酶和脂质过氧化物丙二醛表达的影响，探讨其治疗阿尔茨海默病(alzheimer disease，ad)的作用机制。方法用冈田酸(okadaic acid，oa)注射大鼠侧脑室造模，测定模型组、实验组、对照组海马和皮质tau蛋白、sod、mda的含量。结果实验组tau蛋白低于模型组(p＜0.001)，高于对照组(p＜0.05)；sod高于模型组(p＜0.001)和对照组(p＜0.05)；mda低于模型组(p＜0.001)，高于对照组(p＜0.05)。结论天麻可增强oa致实验性痴呆大鼠脑组织sod活性，降低mda蓄积和tau蛋白生成，具有防治阿尔茨海默病的作用。

Methods The ovaries of rats were irradiated by 50Gy γ-ray to establish the animal model.The lumbar was got after 90 days. Dual energy X-ray absorpt metry was used to measure the bone mineral density. The changes of bone microstructure characters were observed by the scanning electron microscope. Bone biomechanical properties were determined by the maximal loading obtained from the compression test.

方法手术暴露大鼠双侧卵巢并应用50Gy的γ射线局部照射，术后90d取大鼠腰椎，DEXA测定骨密度，扫描电镜显示微结构，并行压缩实验检测腰椎最大载荷。

Objective To study the effect of different doses of levodopa on the flash visual evoked potential of form-deprived amblyopic rats, and to discuss the possible mechanism of amblyopic therapy.

30只14日龄SD大鼠幼鼠，随机分为3组，每组10只，分别为弱视对照组、小剂量给药组及大剂量给药组。3组SD大鼠采用单眼睑缝合30 d建立形觉剥夺眼弱视模型。

Angiosteosis model was established by intragastrical administration of highdose of vitamine D3. Simvastatin group and sesame group were treated by simvastatin and sesame, respectively. Angiosteosis,blood fat and calcium were detected in all groups.

用大剂量VitD3灌胃的方式造成大鼠血管钙化模型，同时分别用辛伐他汀和芝麻进行治疗，比较VitD3模型组和各治疗组大鼠主动脉血管钙化程度及其血脂水平。

Results There were significant difference of autopathy between CV and SPF rats, detection rate was 94%,42.5% in livers,60%, 22.5% in kidneys,32.5%,5% in hearts and hyperplasia percentage in the lymphoid tissue around the bronchial tubes of lungs was 92.31% and 62.5% respectively; There were small focus infection and abnormal tissue changes in SPF rats.

结果普通级与SPF级大鼠均检出自发性感染性病变，且存在较大差异，检出率分别为肝94%、42.5%，肾55%、20%，心22.5%、5%，肺支气管旁淋巴组织增生程度92.31%、62.5%。SPF级大鼠依然存在比较轻微的小灶性感染和非正常组织形态改变。

Then studied the effect of three-different-dose remedy on brachychronic stasis model of rats .Draw the conclusion:NaoXinKang capsule has the effect on restrain the thrombosis of rats .

药效部分，本课题研究了三个剂量组的脑心康胶囊对大鼠血栓形成、凝血时间、血小板聚集、大鼠脑缺血的保护作用、对大鼠急性血瘀模型的血液流变性的影响。

Objective: To observe the motor function variation of focal cerebral ischemical reperfusion injury rats'limbs at different time. To observe the expression of PCNA and VEGF. To observe the effect to that index when electric acupuncture the"Quchi"and"Housanli". To observe the effect to the focal cerebral ischemical reperfusion injury rats, which are inject eNOS catastaltic, when electric acupuncture that two acupoints. Through observing of above all things , we study acupuncture's blood vessel regenerated effect to cerebral ischemia reperfusion injury region, approach the possibility of brain functional recovery angiogenesis which promoted by acupuncture, provide new consider and experiment accordings for deepening acupuncture therapy of the ischemia stroke.

研究目的：通过观察局灶性脑缺血再灌注损伤大鼠不同时间点肢体运动功能的变化及损伤脑组织核心增长蛋白、血管内皮细胞生长因子的表达情况，电针&曲池&、&后三里&穴对以上各指标的影响、电针&曲池&、&后三里&对给予eNOS抑制剂对局灶性脑缺血再灌注损伤大鼠的影响，研究针刺对大鼠脑缺血再灌注损伤区血管再生的作用，探讨针刺促进脑功能恢复的血管生成可能机制，为进一步深化针灸治疗缺血性中风的认识提供新的思路和实验依据。

Methods Myocardial ischemia was induced by subcutaneous injection of ISO (30 mg/kg for two days, once a day). The experimental animals were randomly divided into the normal group, ISO group, positive control group and three crocetin groups (25, 50, 100 mg/kg). Cardiac indexes were examined. The level of LDH, CK, MDA in serum were measured. The content of MDA, GSH-Px and the ATPase activity heart and mitochondria were assayed by colorimetric analysis. The histopathological change of myocardia was investigated by HE staining.

采用大剂量ISOsc诱导产生大鼠急性心肌缺血模型(1SO30mg／kg，每日一次，连续2d)，实验大鼠随机分为正常组、ISO模型组、阳性对照组和3个西红花酸给药组(25，50，100mg／kg)，测定心脏系数和血清中乳酸脱氢酶、磷酸肌酸激酶和丙二醛含量，观察心肌组织谷肮甘肤过氧化物酶、Na^ ，K^ —ATP酶和Ca^2 ，Mg^2 —ATP酶活性及心脏病理改变，观察西红花酸的保护作用。

Transplantation of BMSCs in neonate rats at 24 hours after HIBD has the maximal long-lasting ethological improvement, which is induced by brain damage, and the mechanism may be that early transplantation with BMSCs reduces effectively neuron necrosis and apoptosis, and is helpful for the migration and differentiation of BMSCs.

新生大鼠缺氧缺血性脑损伤后24 h接受骨髓基质细胞移植可最大程度改善脑损伤所导致的远期行为学障碍，其机制可能与早期移植可有效减轻神经元的坏死、凋亡，且有利于骨髓基质细胞的迁移、分化有关。关键词：骨髓基质细胞；细胞移植；缺氧；缺血；脑；新生大鼠

These results suggest that visceral malaise induced by the intraperitoneal injection of LiCl reduce the intake of the five basic taste solutions and have greater effects on the intake of sucrose and NaCl, which are hedonically preferable and profitable for the survival of the animals.

这些结果表明，腹腔内注射LiCl作为一种广泛的能引起大鼠产生内脏不适的有害刺激，腹腔内注射后可以使大鼠对各种味觉溶液的摄入量减少，其中对具有欣快味觉且有利于机体生存的甜味觉和咸味觉物质摄食影响较大。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。