大鼠

Overloaded rat models were established by using abdominal aorta constriction method. The levels of creatinine and urea nitrogen in the rats?? serum as well as those of malonaldehyde and glutathion of the rats?? nephric tissue were measured respectively.

采用腹主动脉缩窄法制备压力超负荷大鼠模型，分别测定大鼠血清肌酐和尿素氮含量及大鼠肾组织匀浆丙二醛、谷胱甘肽含量。

The nephridial tissue of all the rats was taken for pathological examinations.

选用健康雄性SD(Sprague-Dawley)大鼠，腹腔注射8 mL/kg的DEG，于注射前和注射后第2天、5天、7天以及14天尾静脉采血检测血肌酐、尿素氮和CO2结合率(CO2CP)，收集死亡大鼠及第7天和14天处死大鼠的肾组织进行病理检查。

Healthy SD male rats were given DEG with the dose of 8 mL/kg body weight (intraperitoneal injection I.P.). The level of the serum Cr, BUN and CO2CP(CO2 Combining Power CO2CP)were tested before and after the injection the 2nd , 5th , 7th, and 14th day. The nephridial tissue of all the rats was taken for pathological examinations.

选用健康雄性SD(Sprague-Dawley)大鼠，腹腔注射8 mL/kg的DEG，于注射前和注射后第2天、5天、7天以及14天尾静脉采血检测血肌酐、尿素氮和CO2结合率(CO2CP)，收集死亡大鼠及第7天和14天处死大鼠的肾组织进行病理检查。

Dispersing blood stasis and dredging collateral can reduce 24 hour urinary protein, protect the renal function and down-regulate the expression of CTGF mRNA in nephridial tissue.

化瘀通络中药能够显著减少DN模型大鼠24 h尿蛋白，保护DN模型大鼠肾脏功能，并可从基因水平显著降低肾组织CTGF的表达，提示下调CTGF的表达可能是化瘀通络中药保护DN模型大鼠肾功能的重要机制。

RESULTS: Totally 57 rats enrolled in this study, all animals completed Hot pain allergic symptom could not be observed on rats in experimental group during the whole experimental process, but continuously appeared in discharge percentage of nerve fibers at the central end of experimental rat sciatic nerve was remarkably lower than that of the control group 6.79％Sympathetic postganglion nerve fiber budding was not obvious in the slices of entire L4-5 dorsal root neuroganglion of injury side in 6 experimental rats,and basket-shaped cell could not be observed, but sympathetic postganglion nerve fiber budding was obvious in 2 rats in control groups with altogether 41 basket-shaped cells observed.

电生理实验：实验组大鼠坐骨神经中枢端的神经纤维自发放电百分数显著低于对照组(6.79％，46 7％)。③背根神经节切片荧光染色结果：实验组6只大鼠损伤侧L4-5的全部背根神经节切片中看不到明显的交感节后神经纤维芽生，没找到篮状细胞，而在对照组2只大鼠损伤侧L4-5的全部背根神经节切片中可看到明显的交感节后神经纤维芽生，共找到篮状细胞41只。

To investigate the protective effect of anti-endothelin-1 antibody on neurogenetic pulmonary edema,the anti-endothelin-1 antibody was used in the rats which underwent brain injury referring to Marmarous′model.

采用Marmarous脑损伤模型致大鼠重度、弥漫性脑损伤，观察内皮素-1（ET-1）单克隆抗体对弥漫性脑损伤大鼠肺泡隔面积密度及肺水含量的影响，同时用光镜和电镜观察大鼠肺组织形态学改变。

After seven-days nutritional supporting,the rats\' weight change and ascitic fluid was recorded,serum biochemistry index,pancreatic enzyme index, and malonaldehyde concentration were examined,and the pancreatitic tissue were stained with hematoxylin eosin,and histopathologically scored.

营养支持7天后处死大鼠，记录大鼠体重变化及腹水情况，检测大鼠血清生化酶学指标及胰腺酶学指标、丙二醛含量，并将胰腺标本行苏木精伊红染色进行组织病理评分。

Methods Rat bone mesenchymal stem cells were isolated from adult rats bone marrow by Ficoll -Paque density gradients, cultured and amplified in vitro, and then identified by flow cytometry ; Middle cerebral artery occlusion model of regional cerebral ischemia in rats were made by thread embolizing.

方法Fieoll-Paque分离液梯度离心分离大鼠骨髓间质干细胞（rat bone mesenchymal stem cells，rMSCs），经体外培养扩增并流式细胞术鉴定；线拴法制作大鼠大脑中动脉闭塞脑局灶缺血模型，Hoechst33342标记细胞，分别通过静脉移植及立体定向局部移植到大鼠缺血侧纹状体。

Increased concentrations to 2×10〓, 2×10〓mol·L〓, securinine potentiated both basal PS and the magnitude of LTP induced by HFS. 2、Effects of securinine on synaptic transmission in freely moving rats Rats were chronically implanted with a stimulating electrode in the perforant path of hippocampus and a recording electrode in the granule cell of dentate gyrus.

一叶萩碱对清醒自由活动大鼠海马齿状回突触传递活动的影响为了更直接的研究学习记忆与突触效能的关系，我们采取慢性种植电极，在大鼠清醒状态下，观察药物对近生理状态下大鼠突触传递的影响。

objective to search the factors of liver injury via the anit-induced liver injury in rats.methods male sprague-dawley rats,were divided into 4 groups,data were analyzed using a completely randmized factorial anova and linear correlation.results after anit intoxication,the necrosis of hepatic cell and neutrophil infiltration im periportal region of the liver were observed in liver setions.jinshisan can reduce the alt,the tbil.pla2 correlated positively with alt、akp and tbil.conclusion the severity of anit-induced liver injury correlated positively with the pla2.jinshisan can protect against the rat anit-induced liver injury.

目的 拟通过对α－萘异硫氰酸酯诱导大鼠肝损伤发病机理的探讨，对引起肝损伤的因素进行系统的研究。方法选择s-d大鼠，雄性，随机分4组，检测数据以平均值±标准差表示，采用方差分析，相关分析进行统计学处理。结果s-d大鼠经anit染毒后，病理切片显示肝损伤明显，汇管区有大量中性粒细胞浸润。经金石散及地塞米松治疗后，生化指标均有所下降，中药金石散优于地塞米松，血生化指标与pla2活性相关分析显示，呈正相关。结论 anit诱导的肝毒性损伤程度与肝组织匀浆pla2活力呈正相关，应用抑制剂降低pla2活力，肝损伤程度也减轻，中药金石散具有降低pla2活性，减轻肝毒性损伤。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。