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White prepared lateral root of aconite caused different blood biochemical effects on normal and kidney Yang deficient rats, and more remarkable toxicity effect on normal rats.

白附片对正常大鼠和肾阳虚模型大鼠血液生化指标的影响不同,对正常大鼠的毒性效应更明显。

The percentage of through the platform position was calculated. The learning and memory behavior was observed mainly in rats of every group. After the experiment, sodium pentobarbital was injected by intraperitoneal injection of all the rats for anesthesia, and the blood was gained from heart.The plasmcortisol and adrenocorticotrophic hormone were detected by the radioimmunoassay.

取模型组大鼠8只,对照组大鼠5只,不经灌注固定,冰台上迅速分离大脑,将大脑沿矢状缝分左右半球,左半球用于糖皮质激素受体mRNA原位杂交,右半球采用薄层扫描法测定谷氨酸和γ-氨基丁酸含量,同时取大鼠左侧肾上腺进行苏木精-伊红染色,观察肾上腺组织形态变化。

MAIN OUTCOME MEASURES: The condition of survival and rejection of grafts was observed. In the fludarabine + bone marrow transplantation group, tolerance rats received Sprague Dawley rats and Dark Agouti rats skin grafting and cytokine mRNA was detected in splenocytes.

主要观察指标:观察移植物排斥反应征象及存活情况,并对氟达拉滨+骨髓移植组产生免疫耐受大鼠进行SD大鼠及DA大鼠皮肤移植及脾细胞中细胞因子mRNA检测。

The experimental study shows that the FXG can reduce the content of inflammatory factor IL-4 in the serum of bronchial asthma mice in catabasis, and EOS count in the peripheral blood of it, restrain the collection of EOS in bronchi and lung, alleviate air-way tracheospasm and have evident differences compared with ketotifen group.

实验研究结果显示:防哮颗粒能降低哮喘缓解期模型大鼠血清中炎性因子IL-4的含量,明显改善哮喘模型大鼠外周血中EOS计数的异常升高。能抑制支气管和肺脏局部EOS聚集,减轻气道炎性损伤,轻模型大鼠肺组织的病理改变。

Sixty Wistar rats were randomly assigned to receive sham operation, blockage of unilateral ureteral without treatment, or intraperitoneal injection of amygdalin at a dose of 3 mg or 5 mg, and then sacrificed on days 7, 14 and 21 postoperatively, Pathological changes in the kidney in each group were observed.

用单侧输尿管梗阻的方法建立大鼠肾脏间质纤维化模型。60只Wistar大鼠随机分为假手术组、单侧输尿管梗阻组、苦杏仁甙3 mg腹腔注射组和苦杏仁甙5 mg腹腔注射组,分别于术后7、14、21 d处死动物,观察各组大鼠肾脏病理损害程度。

The effects, of protection and treatment with, combined Ch, NaF and a trophie were significantly better than that with atropine alone. In isolated phrenic nerve-diaphragm preparation of rat, isolated jejuneal preparation of, guinea pig, and the metabolic experiment of rat liver, the results of the, assay on the rat blood ChE activity indicated that antidotal effect of NaF may be due to the antidese...

大鼠离体膈神经膈肌、豚鼠离体空肠和大鼠肝脏代谢实验及对大鼠全血胆碱酯酶活力测定的结果表明,NaF的抗毒作用可能是由于其对神经肌肉接头和/或神经节中的N受体的抗脱敏作用;而Ch则可能通过其对ChE的保护和/或加速被抑制ChE的复能,阻碍Ach到达M受体部位而发挥作用。

Methods:All of 40 male Sprague-Dawley rats were divided into 3 groups:control group(group A, n = 10), diabetic group for 4 weeks(group B, n = 14), and diabetic group for 12 weeks(group C, n = 16). The diabetes model was established by the injection of STZ. After some weeks erection function was examined by apomorphine injection. The content of NF-κB in the erectile tissue was evaluated by immunohistochemistry staining. At the same time the activity of NF-κB was detected by electrophoretic mobility shift assay.

将成年雄性SD大鼠40只分为3组:A组为正常对照组(10只),B组为糖尿病4周组(14只),C组为糖尿病12周组(16只),采用腹腔注射STZ法制作糖尿病模型。B组大鼠于4周后,A组、C组大鼠于12周后通过注射阿朴吗啡后评价勃起功能,并取阴茎海绵体组织免疫组化EnVision法分析NF-κB的分布与表达,同时采用电泳迁移率变动分析法进行NF-κB 活性检测。

But in SD rats, cardiac muscle fibers were fractured seriouly , contracted to wavilness obviously, then muscle fibers fracture were contracted like entasia by the hypoxia time increased , injury intensify , all the changes refered SD rats compensatory mechanism can not be transferred in this hypoxia degree. 3. Exposed to 4% oxygen concentration, the cardiac muscle ultrastructure of Gansu zokors had serious injury after hypoxia 2h.

在4%氧浓度的低氧耐受实验中,甘肃鼢鼠在低氧2,4h后,心肌纤维收缩明显呈波浪状,低氧时间延长至6,8和10h后,心肌显微波浪状收缩由强逐渐变弱,并逐渐恢复至正常状态,说明鼢鼠心肌在6h以后对严重缺氧环境开始代偿性适应;SD大鼠2h组心肌纤维断裂严重,收缩加强成明显的波浪状,随着低氧时间得增加,4h组呈严重成挛状收缩,损伤加剧,提示SD大鼠在这一氧浓度下已经无法正常调动其代偿机制。3。

Results Bro (0.5mg/kg, sc) reduced the PRL level and induced the dysplasia of mammary gland in lactational rats. Bro also caused the retardation of the weight growing in newly-born rats. l-tetrahydropalmatine 6 and 18mg/kg ip remarkably increased the prolactin level and promoted the development of mammary gland in lactational rats models and promoted the weight growing in newly-horn rats.

结果 sc Bro 0.5 mg/kg可显著降低哺乳期大鼠血清PRL水平,其仔鼠体重增长缓慢,并且母鼠乳腺组织发育不良。ip l-THP 6mg/kg及18mg/kg可显著提高用Bro造模的哺乳期大鼠血清PRL水平,促进其仔鼠体重增长,并且母鼠乳腺组织发育良好。

Methods: To establish a rat model of pancreaticoduodenal transplantation with venacava endocrine drainage and enteric eccrine drainage. The recipient rats were introperitoneally injected with 15 mg/kg of proline dithiocarbamate in experiment group and with equal amount of normal saline in control group 30 minutes before transplantation.

建立大鼠腔静脉内分泌引流、肠道外分泌引流的动物模型,脯氨酸二硫代氨基甲酸酯组供体胰腺保存在ProDTC的UW液中,受体鼠于移植前30min腹腔注射ProDTC(15mg/kg);对照组供体胰腺仅保存在UW液中,受体鼠腹腔注射等量生理盐水,分别于再灌注后第0、1、3、6、12、24h等时点,处死大鼠,取血后切取移植胰腺。

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