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The results show that: This tablet can decrease the rat"s footpad swell induced by Freud"s, inhibit the permeability of the blood capillary in inflammatory joint and decrease the 11-2 level in serum while increasing the rat"s body weight,(2) It can lower the rat"s temperature and the permeability of the blood capillary in inflammatory joint induced by collagen and inhibit the delayed type hypersensitivity,It can lower the stickiness of full blood and the accumulation of erythrocyte obviously inblood stasis model rats,lt can inhibit the formation of hemolysin and decrease the index of carbon granule clearance in mice, It can lower the permeability of celiac blood capillary and inhibit the granulomatous hyperplasia by sc cotton ,It can inhibit the pain induced by acetic acid and raise the pain threshold value of heat stimulation.

结果表明:关络通片能明显降低佐剂性关节炎大鼠左右足趾肿胀度,降低大鼠炎症关节的通透性,抑制其IL-2含量,对大鼠体重增长缓慢有一定的改善作用;能改善Ⅱ型胶原诱导性关节炎大鼠的表征指标及炎症关节的通透性,对其迟发型超敏反应有一定的抑制作用;对血瘀模型大鼠,能显著性降低其全血粘度、血浆粘度、红细胞压积;能抑制小鼠的溶血素抗体生成,抑制小鼠网状内皮系统的吞噬能力,具有一定的抑制机体免疫功能的作用,能抑制小鼠腹腔毛细血管通透性增高,抑制大鼠棉球肉芽组织增生,具有一定的抗炎作用;能抑制小鼠醋酸扭体反应、提高小鼠热板痛阈值,具有一定的镇痛作用。

RESULTS Xiaocuoling at the concentration of 2.5、5.0、10.0g.kg-1 obviously inhibited the paws swelling induced by carrageenin in mice and the granuloma with cotten pellet in rats,decreased the penetration of blood capillary caused by histamine,increased the activity of peroxide hydrogenase in RBC,reduced the reaction of the torsive body induced by acetic acid in mice,and had no effects on the serum concentrations of testosterone of serum in male rats.

结果:消痤灵颗粒 2.5、5.0、10.0g.kg-1可显著抑制角叉菜胶所致的小鼠足趾肿胀和大鼠棉球肉芽肿,降低由组胺诱导的小鼠皮肤毛细血管通透性的增加,提高红细胞过氧化氢酶的活力。对乙酸致小鼠扭体反应有抑制作用。对雄性大鼠血清睾酮含量无影响。

Results: Shukang granule can obviously resist inflammation induced by dimethylbenzene, egg-white, raise the pain range of mice induced by hot plate , extend the delitescence of mice's turn-body reaction induced by injecting potassium antimony tartrate and decrease the number of times in 10min, restrain the meat-bud of rats formed.

结果:术康颗粒可明显抑制二甲苯所致小鼠耳廓肿胀和大鼠蛋清性足趾肿胀,明显提高小鼠热板法致痛的痛阈,使酒石酸锑钾所致小鼠扭体反应的潜伏期延长,10min内扭体次数减少,对大鼠棉球肉芽肿形成有抑制作用。

Methods:The rats with sepsis was established by administering endotoxin into the peritoneal cavity.The rats were randomly divided into 4 groups as follows:2,6,12 and 24 hours after administration of endotoxin,each group included normal control.We use the in vitro muscle incubation system with sufficient oxygen supply as well as amino acid automatic analyzer for detection of the proteolytic rate of extensor digitorium longus and soleusmuscle.

大鼠腹腔注射内毒素制成脓毒症模型,随机分成内毒素攻击后2、6、12和24小时组,每组设正常对照;利用骨骼肌充分氧供离体孵育系统,采用氨基酸全谱分析仪测定脓毒症大鼠伸趾长肌和比目鱼肌蛋白降解率。

We use the in vitro muscle incubation system with sufficient oxygen supply as well as amino acid automatic analyzer for detection of the proteolytic rate of extensor digitorium longus and soleusmuscle.

大鼠腹腔注射内毒素制成脓毒症模型,随机分成内毒素攻击后2、6、12和24小时组,每组设正常对照;利用骨骼肌充分氧供离体孵育系统,采用氨基酸全谱分析仪测定脓毒症大鼠伸趾长肌和比目鱼肌蛋白降解率。

The present study was performed to observe the time course and features of intermittent tetanic contractile function changes in soleus and extensor digitorum longus muscles of tail-suspended rats. The optimal stimulating frequency, fatigability and time-dependent recovery after fatigue were measured in isolated muscle strips.

为观察模拟失重对大鼠比目鱼肌(soleus, SOL)与趾长伸肌(extensor digitorum longus, EDL)间断强直收缩功能的影响,以及对刺激频率的调节作用,采用离体骨骼肌条灌流技术,观测其产生强直收缩最大张力的最适刺激频率、疲劳性与疲劳后恢复过程。

The C response of semimembranous and semitendinous myoelectricity evoked by stimulation to rat intraplanta with high intensive currents was used to illustrate the peripheral analgesic effect of BmK when given in local cutaneous sensory fields.

方法采用局部皮肤感受野给药,以强电流刺激大鼠后肢趾部诱发半膜半腱肌发放C反应,观察对外周神经系统的镇痛作用;经脊髓蛛网膜下腔给药,以大鼠足跖辐射热痛阈的变化为中枢镇痛效应的观察指标。

Results Qidan Granules could relieve the pain caused by glacial acetic acid and heat stimuli; significantly inhibit the oxytocin-induced dysmenorrheal in mice; It also showed obvious inhibitory effects on the increased capillary permeability induced by glacial acetic acid, carrageen-induced toe edema in rats and dimethylbenzene-induced ear swelling in mice, and cotton pellet-induced granuloma formation in rats. It could also significantly inhibit oxytocin-induced dysmenorrhea in mice.

结果 奇丹颗粒能明显抑制乙酸和热刺激所致的小鼠疼痛反应;对缩宫素所致实验性痛经小鼠具有良好的镇痛作用,对乙酸所致小鼠腹腔毛细血管通透性增高以及大鼠角叉菜胶足趾肿胀、二甲苯所致小鼠耳廓肿胀、大鼠棉球肉芽肿等急慢性炎症模型均有明显抑制作用。

Methods The damaged second metacarpophalangeal joint,distal part of the second metacarpal and proximal part of the proximal phalanx were dissected.The metatarsophalangeal joint was transferred to the region of metacarpophalangeal joint of hand.The dorsal pedis artery Was anastomosed to the radial artery ,and the great saphenous vein Was anastomosed to the cephalic vein at anatomical snuf-box. The dissected bones of the hand removed of the cartilage of joint and soft tissue were grafted back to the donor site of the foot.

手术切除破坏的第二掌指关节及部分第二掌骨和近节指骨,将第二跖趾关节转移至手部第二掌指关节处,在鼻烟窝处将足背动脉与桡动脉吻合、大隐静脉与头静脉吻合,将切除的第二掌指关节的软骨关节面和骨骼的软组织剔除后回植到足部第二跖趾关节供区。

A series of measures, such s uniformly arranging grouting holes for consolidation grouting, monitoring stresses of anchor rods, increasing grouting pressure in stages, automatically warning against the upraising of toe slabs, were taken to make the maximum grouting pressure of first section increase to 1.0 MPa and the factor of safety against seepage of shallow curtain bodies exceed 1.90, building a safe and reliable seepage control system for the soft foundation under concrete face rockfill dam's toe slabs.

通过采用均布固结、锚杆应力监测、分级升压、抬动自动报警等一系列措施,使趾板基础帷幕第1段最大灌浆压力达到1.0MPa,浅部幕体抗渗安全系数超过1.90,建构起安全、可靠的面板坝趾板软岩基础防渗体系。

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