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大脑切除

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MethodsFrom July 1996 to July 2005, 29 cases' meningiomas in the falx brain were resected in addition to blocking artery with silvern clamp, controlled hypotension or preoperatively embolizing blood vessel.

1996年7月—2005年7月对29例大脑镰旁脑膜瘤在手术时应用银夹阻断供血动脉、术中采用控制性低血压或术前行供血血管栓塞;瘤体较大,尽量分块一次切除。

His review of experimental and clinical studies demonstrated that interactions with brain structures were important for the processing of nociceptive information.

完整成熟的大脑皮质有感受疼痛的基本特点,但是该理论因在有明显皮层损伤或半球切除术的患者存在持续感觉而受到挑战[1]。

A craniotomy with the size of 4 cm × 5 cm was placed at the site which corresponds to the sylvian fissure, the circular sulcus was exposed allowing transcortial exposure of the entire ventricular system, thus achieving the functional hemispherectomy.

手术均采用侧裂表面4 cm × 5 cm骨窗开颅,分开侧裂后经皮质进入侧脑室,完成功能性大脑半球切除手术。

In our research,Wistar rats and SD rats which were parathyroidectomized were used as donors and recepients respectively.The parathyroid gland of the Wistar rat were allografted into the cerebroventricle and other different sites of the brains in SD rat s tereotaxically. Using methods of testing serum Ca~(2+) concentration,histological examination,histochemical and immunocytochemical methods and electron microscopic observation,we investigated the survival of the grafting tissue,its revascularization, infiltrating of monocytes, changes of microglia and astrocytes, the relationship of the CNS with the immune system, and the mechanism of rejection were investigated.The results as following: I .Effects on PTG after allografting into cerebroventricle and cerebral parenchyma of the brain: Testing serum Ca~(2+) conc.

本研究以Wistar大鼠作为供体,切除甲状旁腺的SD大鼠作为受体,在立体定位下将同种异体的PTG移植到大脑的不同部位,设计了侧脑室-内分泌系统移植的代替途径,比较了侧脑室内移植和脑实质内移植的异同,通过测定血清Ca~(2+)的浓度、组织学检查、组织化学和免疫细胞化学以及电镜观察对移植后PTG组织的存活、血管的再生、单核细胞的浸润、CNS内胶质细胞的变化、对免疫系统的影响及免疫排斥的机制进行了研究,结果如下:一、同种异体PTG侧脑室内移植与脑实质内移植的比较:血清Ca~(2+)的检查发现,PTG侧脑室内移植后第7天,血清Ca~(2+)的浓度恢复到8mg%以上,一直持续到移植后第8-12周;移植后第12周仍有60%移植PTG的动物血清Ca~(2+)维持在正常水平。

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