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The incidence rate of breast cancer as the second or third primary malignancy associated with MPMNs was 2.3% with the high morbidity age of 50.1 years, intermitting time 7.1 years and the commonly involved organs were uterus, large intestine, ovary and esophagus.

好发器官为肺、子宫、食管、卵巢和大肠。4乳腺癌作为第二、三原发癌的MPMNs发生率2.3%,年龄50.1岁,间隔时间7.1年;第一原发癌好发器官为:子宫、大肠、卵巢和食管。

Results totally 287 strains were isolated from the 256 positive samples , and the gram-negative bacilli were 225(78.4%,), the gram-positive coccus were 41(14.3%), snd the monilia were 21(7.3%).the distributions of clinical bacteria were respiratory tract(63.4%),urinaryract(7.0%),secretion(includingwound .3%),blood(5.9%),stool(5.2%), pucture fluid(4.9%), and other sites(7.3%). of all isolating bacterium,from the first to the fifth were ps.aeruginosa(19.5%),k.pneumoniae(16.7%), e.coli(14.3%), a.baumannii(11.8%) and psemal (10.1%).resistant rates of methecillin-resistant s.aureus,methecillin-resistant coagulase-negative staphylococci and vancomycin-resistantwere 88.2%、70.0% and 11.1% respectively;the incidence of e.coli and k.penumoniae produce extended speutrum beta-lactamase were 68.6%和65.2%, 44.6% of ps.aeruginosa isolates were resistant to imipenem; the highest examining rate of 21 kinds of monilia was candida albicans (66.7%),resistant rate of candida albicans to fluconazole and amphotricin b was 51.3% and 1.3%.

结果 在254份检出细菌阳性标本中共培养出287株细菌,其中革兰阴性杆菌225株(78.4%),革兰阳性球菌41株(14.3%),念珠菌21株(7.3%),检出菌来自呼吸道标本占63.4%,其他标本各占5%左右;细菌检出占构成比前三位的依次为铜绿假单胞菌19.5%、肺炎克雷伯菌16.7%、大肠埃希菌14.3%;耐甲氧西林金黄色葡萄球菌、耐甲氧西林凝固酶阴性葡萄球菌和耐万古霉素的肠球菌的发生率分别为88.2%、70.0%和11.1%;大肠埃希菌和肺炎克雷伯菌的超广谱β-内酰胺酶的检出率分别为68.6%和65.2%,铜绿假单胞菌对亚胺培南的耐药率为40.2%;白色念珠菌对氟康唑的耐药率为81.3%,对两性霉素的耐药率为3.2%。

objective to study the risk factors on esbl producing strains of k.pneumoniae and e.coli.methods aprospective survey on esbl producing strainsof k.pneumoniae and e.coli for a36-month period.results the resistance rates ofe.coli were:98.08%for ctx,73.08%for amc.the resistance rates of k.pneuˉmonialwere;95.74%for ctx,97.87%for amc.the use rate of third generation cephalosporins was much higher than those of esbls nonproducing strains(p.05).it induce esbls that3rd generation cephalosporins were used extensive.after strenghtening the antibiotic controls,esbls detection rate has gone down.conclusion the factors of infection of esbl-producing strains were the severity diseases,cellular immunological condition,improper medical manipulations.to prevent esbl-producing strains,reasonable antibiotics usage may be the effective measure.

目的 分析临床大肠埃希菌及肺炎克雷伯菌产esbls的危险因素,并加以控制。方法前瞻性监测产esbls菌的情况,并对感染者进行临床调查。结果产esbls的大肠埃希菌、肺炎克雷伯菌的耐药率头孢噻肟钠为98.08%和95.74%,阿莫西林+棒酸为73.08%和97.87%,产esbls菌感染者头孢第三代的使用率(70.21%)显著高于非产esbls菌感染者(39.47%)(p.05);第三代头孢的大量使用诱导esbls的产生。通过加强抗感染药物的使用管理esbls检出率开始下降。结论严重的基础病、高龄、机体免疫力低下,长期住院者是esbls菌感染的易感宿主,皮质激素、化疗及介入性疗法是esbls感染的高危因素。滥用抗感染药是产生esbls的重要因素,合理使用抗感染药是防止esbls产生的主要措施。

The minimal bactericidal concentration of PTKE on Escherichia coli, Staphylococcus aureus, Salmonella, Pasteurella multocida and Streptococcus agalactiae were 100, 25, 50, 25 and 50 mg/mL respectively. The isolation of EA, EB and EC had no antibacterial effect on Escherichia coli and Pasteurella multocida. MBC of EA on Staphylococcus aureus and Salmonella were 2.5 and 5 mg/mL, and MBC of EB on Staphylococcus aureus, Salmonella and Streptococcus agalactiae were 1.25, 5 and 2.5 mg/mL respectively, while MBC of EC on Staphylococcus aureus was 2.5 mg/mL. Polygonum taibaishanense Kung.

PTKE对大肠埃希菌、金黄色葡萄球菌、沙门氏菌、多杀性巴氏杆菌和无乳链球菌的最低杀菌浓度分别为100,25,50,25和50 mg/mL;而PTKE的分离物EA、EB和EC对大肠埃希菌和巴氏杆菌无抑菌作用,EA对金黄色葡萄球菌、沙门氏菌的MBC分别为2.5和5.0 mg/mL,EB对金黄色葡萄球菌、沙门氏菌和无乳链球菌的MBC分别为1.25,5.0和2.5 mg/mL,EC对金黄色葡萄球菌的MBC为2.5 mg/mL。

LIT was most commonly confused with malignant tumor, Crohn's disease, lymphoma and periappendicular abscess. There were 2 of 4 patients, who were performed operation. Most of our cases were not definitively diagnosed until the histopathologic examination after surgery and polymerase chain reaction.

大肠结核较易误诊为大肠肿瘤、克罗恩病、淋巴瘤和阑尾周围脓肿。4例剖腹手术者术中仍有2例(50%)被误诊为肿瘤和克罗恩病,即使活检或术后在病理学报告前仍有多数不能确诊。

The history is important to the diagnosis of CICA.The key of saving life is the decompression peritoneocentesis in time.The local treatment of colorectal injury depends on routine of colorectal injury treatment.But if there are some conditions that affect the colorectal transit,the colon should be shortened properly to defecate facilely.Key words colorectal injuries compressed air abdominal pressure

病史对CICA的诊断重要;及时的腹穿减压是挽救生命的关键;压缩空气所致的大肠局部损伤可按常规处理,但如存在浆肌层广泛剥离等影响大肠传输功能时,应适当缩短结肠,使肠内容排出容易。

Finally, the fluorescent intensity was measured by flow cytometry. Results: The E. coli was labeled well by FITC in carbonate buffer. Macrophage can phagocytize E.

结果:FITC能够有效标记大肠埃希菌;小鼠腹腔诱导的巨噬细胞能够吞噬大肠埃希菌,并且在30min时达到最大峰值。

Finally, the fluorescent intensity was measured by flow cytometry. Results: E. coli was labeled well by FITC in carbonate buffer. Macrophage can phagocytize E.

结果:FITC能够有效标记大肠埃希菌;小鼠腹腔诱导的巨噬细胞能够吞噬大肠埃希菌,并且在30min时达到最大峰值。

"In summary, we have found that uninsured and Medicaid patients have a significantly elevated risk of being diagnosed with advanced-stage colorectal cancer, and this was seen consistently through different regions of the colon, as well as the rectosigmoid junction and rectum," he said.

他表示,总而言之,我们已经证实没有保险与接受医疗补助的病患,被诊断罹患末期大肠直肠癌的风险较高,且不论是在大肠、乙状结肠与直肠的哪里个位置都是一样,我们相信针对弱势族群改善筛检与提供其它照护资源可能可以降低这种差异。

"In summary, we have found that uninsured and Medicaid patients have a significantly elevated risk of being diagnosed with advanced-stage colorectal cancer, and this was seen consistently through different regions of the colon, as well as the rectosigmoid junction and rectum," he said.

他表示,总而言之,我们已经证实没有保险与接受医疗补助的病患,被诊断罹患末期大肠直肠癌的风险较高,且不论是在大肠、乙状结肠与直肠的哪个位置都是一样,我们相信针对弱势族群改善筛检与提供其他照护资源可能可以降低这种差异。

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