大核

Results In the medium and high dose F0 groups, it was observed that the atrophy and incrassation of seminiferous tubule, decrease of spermatogenesis, hyperplasia of interstitial tissue, especially in high dose groups spermatozoon abnormality and nucleolus concentration in the rats testis after DU ingestion for 14 months. The changes became more severe with the prolongation of DU ingestion. Such changes occurred in filial rats (F1) after DC ingestion for 5 months. In the medium and high dose F0 groups, it was observed that a little atrophy of kidney glomerulus, hyperplasia of interstitial tissue after DC ingestion for 14 months, and kidney glomerulus fibrosis happened after DC ingestion for 20 months, such changes occurred in filial rats (F1) after DC ingestion for 5 months In the medium and high dose F0 groups, splenic germinal center and periarterial lymphatic sheaths were hyperplasia , companies with lymphopoiesis after DC ingestion for 7 months, splenic white pulp became more small and sparse after DC ingestion for 20 months.

结果 F0代的中、高剂量组大鼠摄入贫铀14个月后可见雄性的精曲小管萎缩，管壁增厚呈空虚网状，生精细胞层次减少，间质细胞增生，但仍见有精子生成；高剂量组可见到精子呈异型性改变，细胞核浓缩深染，且随着摄入时间延长改变愈趋明显；F1代大鼠摄入贫铀5个月后就有上述改变且更为严重。F0代中、高剂量组大鼠摄入贫铀14个月后肾小球轻度萎缩，间质增生明显，20个月时肾小球萎缩纤维化；F1代大鼠摄入贫铀5个月后就有上述改变。F0代中、高剂量组摄入贫铀7个月时脾脏生发中心和淋巴鞘增生，淋巴母细胞增生活跃，20个月时脾小体减少，生发中心稀疏；F1代大鼠摄入贫铀早期和晚期有类似改变。F0和F1代高剂量组摄入贫铀早期肝脏有炎症细胞浸润，晚期骨髓有核细胞减少，脂肪细胞增加。

The three groups were loaded and analyzed under the same loading according to the mean value of the bite force of incisors. RESULTS:(1)The maximum stress of dentin in group A was twice higher than that in group B. The maximum primary stress, minimum primary stress and maximum shear stress of group A were respectively 236.35, 228.83 and 218.05 percent of those in group B. The difference of maximum stress values of group B and group C was neglectable.(2) The maximum stress distribution of dentin in group A and group B was quite different (the stress was concentrated in labial and lingual side of the cervical dentin in group A, otherwise in group B it was concentrated in the area around the alveolar and the labial and lingual side of the dentin which was opposite to the tip of the cast metal post and core). The maximum stress distribution of dentin in group A and group B was almost the same.

结果：(1)从牙本质的应力大小来看，A组中牙本质最大应力值比B组中牙本质最大应力值增大了1倍以上（最大主应力、最小主应力和最大剪切应力A组分别是B组的236.35%、228.83%和218.05%），而B组与C组的牙本质最大应力值相差极小；(2)从牙本质的应力分布位置来看，A组与B组的牙本质最大应力分布位置相差甚远（A组主要集中在牙颈部唇舌侧肩台部的牙本质上，B组主要集中于牙槽嵴顶附近及铸造桩核尾端相对应的唇舌侧的牙本质上），而B组与C组的牙本质最大应力分布几乎在同一位置。

Objective to evaluate the functional recovery of acute spinal cord injuried rats treated with exogenous wnt-3a signal protein administration and to explore its mechanism.methods moderate spinal cord contusion injury was made in 40 adult sprague dawley rats at t10.twenty rats served as contusion controls(group 1).twenty rats were treated with wnt-3a for three days after injury (group 2).the functional recovery of the rats was observed through basso,beattie,bresnahan open field locomotor score.rats were killed at 14 or 28 days after injury,then spinal cords were removed for histopathological examinations,and the expression of the bromodeoxyuridine plus neural cell markers was stained with immunohistochemical method.results rats of two groups receiving a contusive injury recovered substantial function within 1 week.by 28 days,rats in groups 2 scored 7.0 points better on the bbb scores than rats in group 1 group 2=16.94,after 28 days vs.

目的 研究外源性wnt-3a信号蛋白对脊髓损伤的修复作用，并探讨其作用机制。方法取40只成年雌性sd大鼠在t10节段制备适度脊髓挫伤模型。随机从中取20只为损伤对照组(group 1)，另外20只为损伤治疗组(group 2)。脊髓损伤3天后用wnt-3a蛋白治疗。这些大鼠的功能恢复通过basso、beattie、bresnahan开放视野运动评分来观察。这些大鼠分批在损伤后14天或28天被处死，取出损伤节段脊髓用来组织病理学检查，同时用5-溴脱氧尿嘧啶核苷和神经细胞标记物进行免疫组化染色。结果两组大鼠在伤后一周运动功能有明显的恢复。不过，到损伤后28天，我们观察发现，损伤治疗组中的大鼠bbb评分比损伤对照组中的评分高出7.0分左右(group 2∶16.94±1.18，group 1∶9.89±1.29；p.05)，光镜和电镜检查发现wnt-3a蛋白对髓鞘形成和轴突再生有一定的修复效果。

An automatic update system based on semantic web techniques to implement the drug-law checking automatically is proposed in this thesis. The design concept is to use OWL as the knowledge model. To represent the drug law knowledge, we view a drug law as a class of medical status, and we can use classification to implement the decision of drug use legality. This approach simplifies the design of inference engine. The OWL supports the syntax of class inherences, so it can reach the cognitive economy and shorten the drug laws encoding length. The OWL syntax can represent most drug laws style, so the system can just use one document and one inference engine to handle all drug laws rules.

本文导入语意网技术提出一法规检核同步化系统，来实现药品检核规则自动更新的功能，其主要设计理念为以语意网的OWL模型来实作法规检核系统，在法规的知识表徵上，系统将所有的药品规则视为医疗状态的类别，因此判别用药的合法性，便可使用分类运算达成，这简化了推理机的设计；利用OWL支援类别继承的语意，故能形成认知经济性效应，缩小医疗法规机器编码长度；最后OWL的语法能表示大部份规则型态，使得系统可以使用一个文件档，一种推理机模型便能表示所有的法规。

In general, this malaria parasites in the mature or nearly mature erythrocytes, schizonts usually large, occurre in mature erythrocytes with more 20 merozoites most commonly arranged in mass.

两性配子体较大，均为长形，雄性配子体有驱核现象，并使寄主细胞膨胀变大；雌配子体较雄配子体长，有一定的包核现象。

From these analyses, we found that the spectral index is higher than,and gained that the evolution of AGNS could be from high-energy objects to the low-energy objects,such as BL Lac objects to the low-polarizble Quasar. In the paper, we also studied the possible correlations of the redshift and the spectral index and flux densities for different wavebands.

同时本论文还对活动星系核的各波段的流量密度进行了分析，得出：活动星系核的演化是由流量密度大的天体演化到流量密度小的天体；活动星系核的各波段辐射流量存在线性相关性，尤其是BL Lac的各波段辐射流量的线性相关特别突出。

The major clinical manifestation was lymph node enlargement found in all patients. Skin involvement and osteolysis were not frequent. The characteristic finding was leukemic cells with highly indented or lobulated flower-like nuclei in peripheral blood and bone marrow. ATL cells were CD2,CD3,CD4,CD25 positive and CD8 negative. No specific chromosome abnormality or HLA type was found. Seven of 8 patients examined had HTLV-Ⅰ antibody. The HTLV-Ⅰ provirus genome sequence integrated into host cell DNA was amplified by PCR and confirmed by liquid hybridization. All of these results showed that HTLV-Ⅰ was also the etiological agent of ATL in China. One of the 9 cases of ATL was classified as lymphoma type, one as chronic-type, and the rest as acute type.

结果和结论确诊9例ATL，其临床特征主要为淋巴结肿大，皮损及溶骨改变少见，外周血及骨髓出现典型的花瓣状核淋巴细胞，胞体大，核畸形，免疫表型为CD-1、CD+2、CD3+、CD4+、CD-8，还表达CD25等激活标记，染色体核型及HLA分型未发现有规律性的变化。8例ATL中有7例血清HTLV-Ⅰ抗体阳性，应用PCR及液相杂交法可检出整合到宿主细胞DNA中的HTLV-Ⅰ病毒序列，表明在我国HTLV-Ⅰ也是ATL的病因。9例中1例为淋巴瘤型，1例为慢性型，7例为急性型ATL，治疗效果及预后均不良。

Therefore, more electrons close to the core, the interaction between the electrons and the core more, and the self-energy more.

所以与核靠近的壳层上的电子越多，电子与核内静电吸引的排斥力就越大，产生的自能修正就越大。

A planet on the other hand is built up out of the dust that surrounds a star. When a star is formed there is still a disk of gas surrounding it. As this gas cools, it condenses and forms solid grains. These grain particles accrete into large bodies called planetesimals, which then collide and accrete to make protoplanets. These protoplanets evolve into planets like the planets in our own solar system.

行星演化与恒星不同：恒星形成之后，周边的气体尘埃云冷却之后凝结形成，成为行星雏形，众多小行星雏形聚合碰撞，演化成成熟的行星；没有内部的核聚变；质量超过木星13.6倍，就会产生核聚变，如果还未至木星86倍，尚处于棕矮星的阶段，将会向恒星演化；持久的核聚变需要足够大的质量来支撑，温度也不足支撑氢向氦的转变。

Results: From the second days of the operation, the brain swellen overtly. RBC and phagocyte can be seen in the cerebral interstitial space. The adventitia of the brain arteries and the perivascular Virchow￣Robin space dilated irregularly. The neuronal number of hippocampal CAI sector decreased evidently. In some neuron both the nucleus and cytoplasm condensed, chromatin gathered near the nuclear membrane.

结果： 自术后第二天可见脑组织水肿，红细胞溢出及吞噬细胞浸润，小血管壁外膜及Virchow￣Robin间隙增宽，内含大量水肿液，海马CAI区正常神经元数量明显下降，且排列及不整齐，细胞皱缩，核固缩、深染，核染色质聚集，核周囊膨大，胶质细胞增生。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。