大改变

The serum cretonne, serum BUN and uric acid in the patients were measured during 8 weeks. The model of CRF was induced by 5/6 nephrectomy in SD rats. Rats were divided into three groups: Sham group, 5/6 nephrectomized group, 5/6 nephrectomized and calcium dobesilate therapy group.

动物实验部分：建立5/6肾切除大鼠慢性肾衰模型，设立假手术组、5/6肾切除组以及羟苯磺酸钙组，治疗12周后观察大鼠肾功能以及残肾组织病理改变。

But when he reached David, he changed his mind and decided to let the cushite messenger break the bad news of Absalom's death to David.

但是当到了大卫面前，他却改变了心意，让古示人向大卫王报告押沙龙的死。

"Both baseline and final levels of maximal oxygen uptake were discouragingly low, and intervention patients did not change their baseline level of walking separate from the exercise program, despite considerable education and encouragement."

"尽管有很大程度上的教育和鼓励意义，但最大耗氧量的基线和最终水平都非常低，干预的病人的行走和锻炼后基线水平没有什么改变。"

"Both baseline and final leels of maximal oxygen uptake were discouragingly low, and interention patients did not change their baseline leel of walking separate from the exercise program, despite considerable education and encouragement."

"尽管有很大程度上的教育和鼓励意义，但最大耗氧量的基线和最终水平都非常低，干预的病人的行走和锻炼后基线水平没有什么改变。"

Results The behavioral features of the aged learning and memory impaired rats were as follow: 1 There was little change happened to the sample performance. 2 The spatial reference memory had obviously declined. The swimming times of searching the hidden platform in the place discrimination performance, the swimming time in a 40cm annulus at the primary platform place (A40T) and the platform crossings in the probe trial performance were the most suitable indexes for mirroring the spatial reference memory abilities. 3 The spatial working memory had not decreased so clearly.

结果 老年学习记忆损害大鼠的行为学改变特征为：1简单学习记忆任务的学习能力没有明显变化。2空间参考记忆能力明显减退，寻找平台所用的游泳时间，40cm环内游泳时间(A40T)和平台跨越次数是反映老年学习记忆害大鼠空间参考记忆能力的理想指标。3空间工作记忆能力减退不明显。

Results indicates,these six kinds of naphthalene sulfonic acidformaldehyde condensation product quaternary ammonium salts have excellent dispersiveness,as well as water-reducing and strength-increasing abilities.

前期研究结果表明：混凝土聚合物型外加剂中金属离子的改变对其性能有较大影响。与金属离子相比，季铵阳离子在分子结构、空间体积、亲水性等方面具有更大的可变性。

The endermic LD50 to rat and mouse were 926 mg/Kg and 1210 mg/Kg respectively. The results of subscute toxicity test in rats showed that the content of blood urea nitrogen in exposure groups was higher than that in control group, the histopathological changes of testis observed in exposure groups were obvious. Mutagenic tests including bacillus subtilis DNA rec-assay, micronucleus ...

其大、小鼠经皮LD_(50)分别为926mg/kg和1210mg/kg；大鼠90天经皮染毒，试验组BUN含量高于对照组，光镜下，试验组睾丸的组织学结构有明显改变；枯草杆菌DNA重组试验、小鼠骨髓多染红细胞微核试验和小鼠睾丸染色体畸变分析试验均获得阳性结果。

OVCs were isolated by density ladder centrifugation in the 4th week, and then OVC's morphology was observed under transmission electromicroscrope and immunocytochemistry were performed to detect the expression of ICAM-1. Results Observing OVC's morphology under transmission electromicroscrope showed that OVC was infantile and undifferentiated with big nucleus, clear nucleolus, large nucleoplasm-ratio, small mitochondria, and little endoplast.

结果 透射电镜下观察到OVCs超微结构的改变为核大，核/浆比大，核仁小，胞浆内细胞器少，可见少量内质网和小线粒体，整个细胞呈幼稚、未分化状态；ICAM-1免疫细胞化学检测阳性；损伤肝组织HE染色和ICAM-1免疫组化检测显示，肝损伤初期，Hering管周围OVCs增生并且ICAM-1阳性表达，随着肝损伤的加重，OVCs继续增生，并且，OVCs沿增生的肝纤维向肝小叶迁移，同时，ICAM-1阳性表达也继续增多，并逐渐向肝小叶弥散分布；透射电镜下观察到，肝损伤初期，OVCs在Hering管周围增生，肝纤维随之增生，增生的OVCs与肝纤维黏附生长。

OVCs were isolated by density ladder centrifugation in the 4th week, and then OVC's morphology was observed under transmission electromicroscrope and immunocytochemistry were performed to detect the expression of ICAM-1. Results Observing OVC's morphology under transmission electromicroscrope showed that OVC was infantile and undifferentiated with big nucleus, clear nucleolus, large nucleoplasm-ratio, small mitochondria, and little endoplast. In initial stage of damaged liver, OVCs and the expression of ICAM-1 mostly distributed around Hering duct, and then gradually increased and expanded toward hepatic lobule, shown by staining paraffin sections with HE, immunochemistry and transmission electromicroscrope. Immunocytochemistry indicated that ICAM-1 expression on OVCs was positive.

结果 透射电镜下观察到OVCs超微结构的改变为核大，核/浆比大，核仁小，胞浆内细胞器少，可见少量内质网和小线粒体，整个细胞呈幼稚、未分化状态；ICAM-1免疫细胞化学检测阳性；损伤肝组织HE染色和ICAM-1免疫组化检测显示，肝损伤初期，Hering管周围OVCs增生并且ICAM-1阳性表达，随着肝损伤的加重，OVCs继续增生，并且，OVCs沿增生的肝纤维向肝小叶迁移，同时，ICAM-1阳性表达也继续增多，并逐渐向肝小叶弥散分布；透射电镜下观察到，肝损伤初期，OVCs在Hering管周围增生，肝纤维随之增生，增生的OVCs与肝纤维黏附生长。

Results Observing OVC's morphology under transmission electromicroscrope showed that OVC was infantile and undifferentiated with big nucleus, clear nucleolus, large nucleoplasm-ratio, small mitochondria, and little endoplast. In initial stage of damaged liver, OVCs and the expression of ICAM-1 mostly distributed around Hering duct, and then gradually increased and expanded toward hepatic lobule, shown by staining paraffin sections with HE, immunochemistry and transmission electromicroscrope. Immunocytochemistry indicated that ICAM-1 expression on OVCs was positive.

结果 透射电镜下观察到OVCs超微结构的改变为核大，核/浆比大，核仁小，胞浆内细胞器少，可见少量内质网和小线粒体，整个细胞呈幼稚、未分化状态；ICAM-1免疫细胞化学检测阳性；损伤肝组织HE染色和ICAM-1免疫组化检测显示，肝损伤初期，Hering管周围OVCs增生并且ICAM-1阳性表达，随着肝损伤的加重，OVCs继续增生，并且，OVCs沿增生的肝纤维向肝小叶迁移，同时，ICAM-1阳性表达也继续增多，并逐渐向肝小叶弥散分布；透射电镜下观察到，肝损伤初期，OVCs在Hering管周围增生，肝纤维随之增生，增生的OVCs与肝纤维黏附生长。

Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势，并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。