大改变

Changes in distribution of unobservable characteristicsof people cause little effects.

参与选择方程行为参数的改变，以及教育选择方程参数的改变对收入分布的影响都非常大，尤其是后者。

Gelatin zymography was used to detect the activation and secretion of MMP-2 and MMP-9 in gastroenemius、soleus、plantaris during early、intermediate and final stage of experimental group. Picric- sirius red polarized light was used to detect the accrementition and reconstitution of mesenchymal fibers in the muscle specimens from the operated group and normal controls.

3采用RT-PCR和Western blot及免疫组化的方法分别检测不同时期的大鼠骨骼肌中核因子κB、MMP-2、MMP-9的表达；采用明胶酶谱的方法检测实验组大鼠早、中、晚期腓肠肌、比目鱼肌、跖肌MMP-2、MMP-9活化、分泌情况；天狼猩红-偏振光法检测大鼠骨骼肌间质纤维增生及成分改变。

Apparently, the giant panda's evolution from Ursus to Ailuropoda required the change of only a few genetic messages (5 or 6 perhaps), yet the phenotypic and lifestyle change from a standard bear is considerable. The transition could therefore be effected relatively swiftly.

显然，从熊到大熊猫的进化只需要少数遗传信息（也许5或6个遗传信息）的改变；然而，在表型和生活方式上与一头标准熊相比，发生了相当大的改变；而且这种转变过渡可能是相对迅速地达到的。

The anisotropical characteristics of metal rubber elements performed under loadings in different directions were researched, and physical hypothesis were provided for the analysis of inner structure of metal rubber material The main parameters for the analysis of anisotropical performance were confirmed according to the previous hypothesis and tested experimentallyThe results show that variety of the relative heights and the radius of MR elements affect the radial stiffness of MR isolator When isola...

研究了金属橡胶构件在不同方向的载荷作用下表现出来的各向异性，提出了用于分析金属橡胶材料内部结构的物理假设，并根据假设确定了各向异性研究的主要参数，然后通过实验研究进行了验证。实验结果表明，如果改变金属橡胶元件的相对高度，增加径向尺寸可以在很大范围内改变金属橡胶隔振器的径向刚度；要使金属橡胶隔振器的力学特性更近于线性，应让隔振器在径向范围内工作；如果隔振系统中含有多个承受压载荷的金属橡胶隔振器，则可以使其工作在与成型压力方向相垂直的方向。当相同结构和尺寸的钢元件和金属橡胶元件在承受剪切载荷作用时，这两种材料表现出了相同的刚度变化趋势。

Results There were significant difference of autopathy between CV and SPF rats, detection rate was 94%,42.5% in livers,60%, 22.5% in kidneys,32.5%,5% in hearts and hyperplasia percentage in the lymphoid tissue around the bronchial tubes of lungs was 92.31% and 62.5% respectively; There were small focus infection and abnormal tissue changes in SPF rats.

结果普通级与SPF级大鼠均检出自发性感染性病变，且存在较大差异，检出率分别为肝94%、42.5%，肾55%、20%，心22.5%、5%，肺支气管旁淋巴组织增生程度92.31%、62.5%。SPF级大鼠依然存在比较轻微的小灶性感染和非正常组织形态改变。

Methods Myocardial ischemia was induced by subcutaneous injection of ISO (30 mg/kg for two days, once a day). The experimental animals were randomly divided into the normal group, ISO group, positive control group and three crocetin groups (25, 50, 100 mg/kg). Cardiac indexes were examined. The level of LDH, CK, MDA in serum were measured. The content of MDA, GSH-Px and the ATPase activity heart and mitochondria were assayed by colorimetric analysis. The histopathological change of myocardia was investigated by HE staining.

采用大剂量ISOsc诱导产生大鼠急性心肌缺血模型(1SO30mg／kg，每日一次，连续2d)，实验大鼠随机分为正常组、ISO模型组、阳性对照组和3个西红花酸给药组(25，50，100mg／kg)，测定心脏系数和血清中乳酸脱氢酶、磷酸肌酸激酶和丙二醛含量，观察心肌组织谷肮甘肤过氧化物酶、Na^ ，K^ —ATP酶和Ca^2 ，Mg^2 —ATP酶活性及心脏病理改变，观察西红花酸的保护作用。

All kind of structure changes do not occur at the same time, for example the epithelial desquamation occurring after exposure for 1 week and sub- epithelial fibrosis occurring after exposure for 8 weeks, and it is incomplete that the prevention of inhaled corticosteroids on airway remodeling. So inhaled corticosteroids should be introduced to treat asthma as early as it possible.

5哮喘气道重塑过程中，气道结构的各种改变是不同步的，气道上皮脱落在激发1w后即可发生，而上皮下纤维化在激发sw后出现，且ICS对气道结构改变的防治是不完全的，故临床上应及早使用ICS治疗，并结合其他抗炎剂如白三烯受体拮抗剂以最大程度地防治气道重塑的发生。

The big difference between these two alternatie ways that tumour cells use to inactiate tumour suppressor genes is that, while the reersal of genetic alterations is technically almost unfeasible in clinical scenarios, the function of these epigenetically inactiated suppressor genes is easily reactiated by pharmacological means.

这两种改变方式最大的不同之处在于肿瘤细胞利用失活的肿瘤抑制基因，而在同时相反的遗传学改变在临床方案上是很难实施的技术。

Based on an analysis of distribution pattern of hydrocyclone"s axial velocity, by changing the inlet flow rate Qi and split ratio Fand making an investigation in the effect of Qi and F on axial velocity field, the factors causing the forming of short-cut circuit and circulating flow are found. It is considered that the short-cut circuit and circulating flow are produced by the structure of the hydrocyclone, and can"t be eliminated completely, though they interfere the flow field inside a hydrocyclone and affect the separation accuracy. Test results show that, by increasing Qi and F and controlling them in a certain range, the separation efficiency of the hydrocyclone can be improved.

在研究旋流器轴向速度分布规律的基础上，分析了短路流与循环流的形成原因，试验研究了改变操作参数，即改变入口流量Qi与分流比F对轴向速度场的影响认为短路流与循环流是由旋流器结构决定的，很难完全消除，它们干扰了旋流腔和大锥段的流场，在一定程度上也影响了分离精度试验结果表明，加大入口流量Qi与分流比F，并将其控制在一定范围内，便可提高分离效率这项研究对水力旋流器分离机理的认识与实际应用均有重要意义

Results. Semiquantitative assessment of histologic changes indicated that 4-week-old rabbit was equivalent to fetus to 2-year-old human and 160-week-old rabbit was equivalent to 11- to 30-year-old human, particularly 11- to 16-year-old, which corresponds to transition period from notochordal to fibrocartilaginous NP.

结果：组织学改变上的半定量测定显示，4个月的兔子相当于2岁的孩子，160个月大的兔子相当于11到30岁大的成人，尤其相当于11到16个月大，相对地，这段时间正好是脊索向纤维软骨NP转换的时期。

They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性，但我大喊，并在他们的方向扔石头让他们过的线索，远离我，以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。