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We examined the effects and mechanisms of methyl pentyl 1,4-dihydro-2,6-dimethyl-4-(3-notrophenyl)-3,5-pyridinedicarboxylate (Mn9202), a novel DHPs calcium antagonist and lacidipine on the 5-HT2B receptor in cultured rat stomach fundus smooth muscle cells.

本研究以富含5-HT_(2B)受体的大鼠胃底平滑肌细胞为模板,观察了二氢吡啶类钙拮抗剂2,6-二甲基-4-(3-硝基苯基)-1,4-二氢-3,5-吡啶二羧酸-3-甲酯-5-正戊酯(Mn9202)、拉西地平对 5-HT_(2B)受体功能的影响,并对其影响机制进行了较为深入的研究。

Objective: To study the espression of pepsinogen C gene in epithelial cells in developing rat stomachs.

目的:研究胃蛋白酶原基因C在大鼠胃底腺发育过程中上皮细胞的表达。

Methods: In this study, the ontogeney of pepsinogen producing cells in rat fundic glands was studied by in situ hybridization vsing a digoxigeninlabeled RNA probe.

采用地高辛标记的RNA探针,用原位杂交的方法研究了大鼠胃底腺中胃蛋白酶C产生细胞的个体发育。

Methods Thirty male Sprague-Dawley rats underwent craniotomy and microsurgery through right subtemporal approach and then cavernous sinus part and post cavernous sinus part of oculomotor nerve were exposed clearly. Results On emerging from the brain, the oculomotor nerve was invested with a sheath of pia mater, and enclosed in a prolongation from arachnoid.

选用健康雄性SD大鼠30只,经右侧颞底入路,显微手术解剖、暴露动眼神经海绵窦段或海绵窦后段,行动眼神经切断并通过动眼神经功能测定,研究手术入路和应用解剖以及降低动物死亡率和减少并发症的方法。

The outer bay received little disturbance and the community was most stable. The community belongs to Group Ⅲ that was dominated by polychaete and characterized as complicated and variable. The community change in the central bay was more complicated, concentrated mainly around Maiban Zhou.

该群落的稳定性最差,处于较强烈的扰动之中;稳定分布于湾口的群落Ⅲ稳定性最好,未受到扰动,以多毛类为主,种类组成较为复杂、变化较大;湾中部海域大型底栖动物群落结构变化较为复杂,主要变化区域为马鞭州附近海域。

For example, prenatal fluoxetine exposure significantly altered the density of 5-HT transporters in subregions of the hypothalamus (dorsomedial nucleus,-21%; lateral hypothalamus,+21%), hippocampus (CA2,+47%; CA3,+38%), and amygdala (basolateral nucleus,+32%; medial nucleus,+44%) in prepubescent offspring.

比如,孕期氟西汀的使用显著地改变了青春期前后代大鼠的下列区域的5-羟色胺转运体密度:下丘脑(背内侧核,-21%,外侧下丘脑,+21%),海马(CA2,+47%;CA3,+38%)和杏仁核(底侧核,+32%,内侧核,+44%)。

This essay analyzes the method and procedure of ice-making recorded in Huai Nan Wan Bi Shu, and creatively proposes that the principle of "ice-making in summer" is refrigeration through the quick evaporation of water to absorb heat under low pressure, and that ice is made on the fine silk at the mouth of an urn, but not inside the urn at its bottom as it was conventionally thought. The essay points out three necessary conditions which should be fulfilled in order to realize "making ice in summer": low relative humidity (less than 26%), large volume of the urn (about 100 L) and proper air temperature (about 20℃).

分析《淮南万毕术》所载制冰方法和过程,提出低压下水快速蒸发吸热制冷是"夏造冰"的制冰原理;结冰的部位不是传统观点所认为的瓮底,而是在瓮口的嫌上;指出要实现"夏造冰",需满足三个条件:相对湿度低(低于26%)、瓮的容积大(100升左右)、空气的温度适当(20℃左右)。

Famous French writer Alexandre be adapted into novel from the "Iron Man" is sweeping the world. 1717 philosopher Voltaire by calling prince regent Orleans Duke also had been imprisoned in the prison bus to 11 months.

法国着名作家大仲马将此改编成小说,从此《铁面人》便风靡世界。1717年哲学家伏尔泰因讥讽摄政王奥尔良公爵,也曾被囚禁在巴士底狱达11个月之久。

The tongs all passes in the machine the gearing on the bed what tongs the gearing on realizes with superficial contact in the cowgirl on the bed in machine or matches.when the tongs installs in the machine bed work on the stage,the center of gravity of the tongs should be as far as possible low,center of gravity the more high an accepts should the dint is more big,the tongs bottom four directions should bulge,make its contact good,or the bottom establishes four a feets.when the tongs installs on the machine bed principal axis,the tongs install the to should have the enough match accuracy with principal axis cowgirl surface,and guarantee the gearing the stability dependable.

夹具体在机床上的安装都是通过夹具体上的安装基面与机床上的相应表面的接触或配合实现的。当物流设备需要的公司体在机床工作台上安装时,夹具的服装厂应尽量低,重心越高则支承面应力越大,夹具底面四边应凸出,使其接触良好,或底部设置四个支脚。当夹具体在机床主轴上安装时,夹具安装基面与主轴相应表面应有足够的配合精度,并保证安装稳定可靠。

Calculation results show that peaks of the maximum principal stresses move toward the surface of chamber after reinforcement, with the self-bearing capacity of rock increased and the plastic zone decreased. In addition, displacement of walls reaches 41.4 mm, that of roof, 22.1 mm, and that of heave, 6.45 mm. Further more, force of supports is in a rational scope.

采用FLAC(上标 3D)软件对原支护方案和返修加固方案进行了数值模拟,结果表明:修复加固后,最大主应力峰值外移,塑性区范围减小,围岩承载能力增强,两帮移近量41.4mm,顶板移近量22.1mm,底鼓量6.45mm,支护受力合理。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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